Opportunity Information: Apply for PA 13 192
Apply for PA 13 192
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Structural Interventions, Alcohol Use, and Risk of HIV/AIDS (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
- This funding opportunity was created on Apr 11, 2013 and posted on Apr 11, 2013.
- Applicants must submit their applications by May 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Small businesses Special district governments State governments Independent school districts For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) City or township governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The National Institutes of Health (NIH) funding opportunity PA 13 192, titled "Structural Interventions, Alcohol Use, and Risk of HIV/AIDS (R21)," supported exploratory research on how changing the broader environment around alcohol use can reduce the risk of HIV transmission. Instead of focusing only on individual behavior change, the FOA emphasized structural and environmental approaches that modify the contexts where alcohol is consumed or sold, or the social and policy conditions that shape alcohol-related risk. The core idea is that alcohol use can increase HIV vulnerability through pathways like impaired judgment, higher likelihood of unprotected sex, and increased exposure to risky settings, so interventions that alter the settings, systems, or rules surrounding drinking may reduce HIV risk at a population level.
This announcement specifically encouraged R21 applications, meaning it was aimed at early-stage, developmental, or high-impact exploratory projects that could generate new evidence, pilot data, or proof-of-concept results. NIH noted that structural and environmental interventions have already shown success in reducing various alcohol-related harms, but that applying these strategies specifically to HIV/AIDS prevention was still relatively underdeveloped. The FOA was therefore positioned to help build the science around whether, when, and how these structural interventions can measurably lower HIV transmission risk, and to identify mechanisms, implementation challenges, and contexts where they work best. It also ran in parallel with an R01 FOA of identical scientific scope, signaling that smaller exploratory projects (R21) and larger, more definitive projects (R01) were both being encouraged under the same overall research theme.
The opportunity fell under the health funding activity category and was tied to CFDA number 93.273 (Alcohol Research Programs). It did not require cost sharing or matching. The award ceiling listed was $200,000, consistent with the R21 mechanism typically supporting limited budgets for shorter, exploratory work. The FOA was posted and created on April 11, 2013, with an original and current closing date of May 7, 2016, and it was archived on June 7, 2016, meaning it is no longer open for applications.
Eligibility was broad and included many types of U.S. and non-U.S. organizations. Domestic eligible applicants included nonprofit organizations (both 501(c)(3) and non-501(c)(3)), public and private institutions of higher education, small businesses, for-profit organizations (other than small businesses), and multiple levels of government (state, county, city/township, special district, and independent school districts). Public housing authorities and Indian housing authorities were also eligible, as were federally recognized Native American tribal governments and tribal organizations. The FOA also explicitly included a wide range of additional eligible applicants such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander-serving institutions (AANAPISIs), as well as faith-based and community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. Importantly, foreign organizations and foreign institutions were eligible to apply, and foreign components of U.S. organizations were allowed under NIH policy, which opened the door to studies in international settings where alcohol-related HIV risk may be especially pronounced.
Operationally, NIH provided an official link to the full announcement at http://grants.nih.gov/grants/guide/pa-files/PA-13-192.html, and listed the NIH Office of Extramural Research (OER) webmaster as the point of contact for technical difficulties accessing or linking to the announcement (FBOWebmaster@OD.NIH.GOV). Overall, this FOA was designed to accelerate research that treats HIV prevention as not only an individual-level challenge, but also a systems and environment challenge, by testing whether changes to alcohol-related environments and structures can reduce HIV/AIDS transmission risk in real-world conditions.
Frequently Asked Questions (FAQs)
What is the NIH funding opportunity PA-13-192?
PA-13-192 is a National Institutes of Health (NIH) Funding Opportunity Announcement (FOA) titled "Structural Interventions, Alcohol Use, and Risk of HIV/AIDS (R21)." It supported exploratory research focused on reducing HIV transmission risk by changing the broader environments and structural conditions connected to alcohol use, rather than focusing only on individual behavior change.
What kind of projects was this FOA trying to support?
This FOA encouraged projects that test structural and environmental interventions related to alcohol use and HIV risk. The emphasis was on modifying contexts where alcohol is consumed or sold, or the social and policy conditions that shape alcohol-related risk, to reduce HIV vulnerability at a population level.
What does "structural intervention" mean in the context of this opportunity?
In this FOA, a structural intervention refers to approaches that change systems, settings, environments, or rules that influence alcohol use and associated HIV risk. The central concept is to reduce risk by altering conditions around drinking (for example, the contexts where alcohol is consumed or sold, or broader social and policy conditions) rather than relying only on individual-level interventions.
Why did the FOA focus on alcohol use as a pathway to HIV risk?
The FOA highlighted that alcohol use can increase HIV vulnerability through pathways such as impaired judgment, a higher likelihood of unprotected sex, and increased exposure to risky settings. Because alcohol-related risk can be shaped by environments and policies, interventions that change these contexts may reduce HIV risk at a broader, population level.
What NIH grant mechanism did PA-13-192 use?
This FOA specifically encouraged applications under the R21 mechanism, which is typically used for early-stage, developmental, or high-impact exploratory research intended to generate new evidence, pilot data, or proof-of-concept results.
How does an R21 fit the goals of this FOA?
The R21 mechanism aligned with the FOA's goal of building the science base around structural interventions for HIV prevention connected to alcohol use. It was intended to support exploratory studies that could clarify whether, when, and how these interventions reduce HIV risk, and to identify mechanisms, implementation challenges, and the contexts where they work best.
Was there a related R01 opportunity for the same topic?
Yes. This FOA ran in parallel with an R01 FOA of identical scientific scope. That signaled NIH interest in supporting both smaller exploratory projects (R21) and larger, more definitive studies (R01) under the same overall research theme.
What was the maximum award amount (award ceiling) listed?
The award ceiling listed for this R21 opportunity was $200,000, consistent with the R21 mechanism typically supporting limited budgets for shorter, exploratory work.
Was cost sharing or matching required?
No. The FOA stated that cost sharing or matching was not required.
What funding activity category and CFDA number was associated with this FOA?
The opportunity fell under the health funding activity category and was tied to CFDA number 93.273 (Alcohol Research Programs).
Is PA-13-192 currently open for applications?
No. The FOA is no longer open. It had an original and current closing date of May 7, 2016, and it was archived on June 7, 2016.
When was this FOA created and posted?
The FOA was created and posted on April 11, 2013.
Who was eligible to apply (in general terms)?
Eligibility was broad and included many types of U.S. and non-U.S. organizations, including nonprofit and for-profit entities, institutions of higher education, small businesses, multiple levels of government, tribal governments and tribal organizations, public housing authorities and Indian housing authorities, U.S. territories or possessions, eligible federal agencies, and various community-based, faith-based, regional, and minority-serving institutions.
Were U.S. nonprofit organizations eligible?
Yes. Domestic eligible applicants included nonprofit organizations, including both 501(c)(3) and non-501(c)(3) nonprofits.
Were colleges and universities eligible?
Yes. Public and private institutions of higher education were eligible applicants.
Were small businesses and for-profit organizations eligible?
Yes. Small businesses were eligible, and for-profit organizations (other than small businesses) were also eligible.
Were government entities eligible to apply?
Yes. Eligible applicants included multiple levels of government, including state, county, city/township, special district governments, and independent school districts.
Were tribal governments and tribal organizations eligible?
Yes. Federally recognized Native American tribal governments and tribal organizations were eligible.
Were public housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities were listed as eligible applicants.
Were minority-serving institutions explicitly included?
Yes. The FOA explicitly included Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander-serving institutions (AANAPISIs).
Were faith-based and community-based organizations eligible?
Yes. The FOA explicitly included faith-based and community-based organizations.
Could foreign organizations apply?
Yes. The FOA stated that foreign organizations and foreign institutions were eligible to apply.
Were foreign components of U.S. organizations allowed?
Yes. Foreign components of U.S. organizations were allowed under NIH policy, enabling studies in international settings where alcohol-related HIV risk may be pronounced.
Where can the full FOA text be found?
NIH provided an official link to the full announcement at: http://grants.nih.gov/grants/guide/pa-files/PA-13-192.html.
Who was the point of contact for technical difficulties accessing or linking to the announcement?
The NIH Office of Extramural Research (OER) webmaster was listed as the contact for technical difficulties accessing or linking to the announcement: FBOWebmaster@OD.NIH.GOV.
What was the overall aim of this FOA?
The FOA aimed to accelerate research that treats HIV prevention as both an individual-level and a systems-and-environment challenge, by testing whether changes to alcohol-related environments and structures can reduce HIV/AIDS transmission risk in real-world conditions.
Did this FOA suggest that structural and environmental interventions already have evidence of success?
Yes. NIH noted that structural and environmental interventions have shown success in reducing various alcohol-related harms, while emphasizing that applying these strategies specifically to HIV/AIDS prevention was still relatively underdeveloped.
What types of research questions did NIH want explored under this FOA?
Based on the FOA description, NIH was interested in research that could determine whether structural interventions can measurably lower HIV transmission risk, and that can identify mechanisms of impact, implementation challenges, and the contexts in which these interventions work best.
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