Opportunity Information: Apply for PAR 13 298
Apply for PAR 13 298
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Revisions to P50 Awards for Research on Detection of Pathogen Induced Cancer (DPIC) (P50)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.394 Cancer Detection and Diagnosis Research.
- This funding opportunity was created on Aug 6, 2013 and posted on Aug 6, 2013.
- Applicants must submit their applications by Dec 11, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $150,000.00 in funding.
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education City or township governments State governments For profit organizations other than small businesses Public housing authorities/Indian housing authorities Special district governments Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Independent school districts Small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The grant opportunity titled "Revisions to P50 Awards for Research on Detection of Pathogen Induced Cancer (DPIC) (P50)" (Funding Opportunity Number PAR-13-298) is an NIH discretionary grant announcement that specifically invites competing revision applications from organizations that already hold an active NIH P50 Center award. The intent is not to fund brand-new centers, but to support an added, expanded line of work within an existing P50 center through a revision that meaningfully broadens the overall scientific scope of the parent award. In practical terms, applicants are expected to propose an additional project that integrates with, and strengthens, the center as a whole rather than a small add-on that sits on the margins of existing activities.
Scientifically, the FOA targets research aimed at improving the detection of pathogen-induced cancers by focusing on how carcinogenic pathogens interact with both the human microbiome and the host. A central emphasis is the discovery and assessment of molecular signatures that can indicate risk or enable early detection of cancers driven by infectious agents, as well as signatures tied to chronic inflammation that may contribute to progression from earlier disease states to invasive cancer. The scope therefore spans mechanisms and biomarkers across host-pathogen-microbiome interactions, with a strong translational angle toward detection and risk stratification for pathogen-associated malignancies.
The program is categorized under the NIH funding activity area of Education/Health and is aligned with CFDA 93.394 (Cancer Detection and Diagnosis Research). It does not require cost sharing or matching. The posted and creation dates were August 6, 2013, with an original and final closing date of December 11, 2015, and an archive date of January 11, 2016, indicating the opportunity is now archived and no longer accepting applications. The listed award ceiling is $150,000, which signals that the revision component is intended to be relatively targeted in budget compared with full center awards, while still large enough to support a meaningful added project.
Eligibility is broad across many U.S.-based organizational types, but it is fundamentally limited to currently funded NIH P50 Centers because this is a revision mechanism. Eligible applicant categories include state, county, city/township, special district, and certain housing authorities; public and private institutions of higher education; independent school districts; nonprofit organizations with or without 501(c)(3) status; for-profit organizations other than small businesses; and small businesses. The FOA also explicitly notes additional eligible applicant types such as HBCUs, Hispanic-serving institutions, AANAPISI institutions, Alaska Native and Native Hawaiian Serving Institutions, tribally controlled colleges and universities, tribal governments and tribal organizations (including some categories beyond federally recognized tribes), regional organizations, U.S. territories or possessions, and faith-based or community-based organizations. At the same time, foreign participation is restricted: non-U.S. entities are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed.
Administrative oversight is through the National Institutes of Health. The FOA points applicants to the full announcement on the NIH Grants Guide website and provides NIH Office of Extramural Research (OER) webmaster contacts for access or linking issues. Overall, the opportunity is best understood as a focused, time-limited mechanism that allowed existing NIH-funded P50 centers to competitively add a new project aimed at advancing molecular and microbiome-informed approaches for identifying risk and enabling earlier detection of cancers caused by carcinogenic pathogens, particularly where chronic inflammation plays a role in progression.
Frequently Asked Questions (FAQs)
What is the official title and funding opportunity number for this grant?
The opportunity is titled "Revisions to P50 Awards for Research on Detection of Pathogen Induced Cancer (DPIC) (P50)" and the Funding Opportunity Number (FON) is PAR-13-298.
What type of NIH funding opportunity is this?
This is an NIH discretionary grant announcement that invites competing revision applications to existing NIH P50 Center awards.
Is this opportunity for creating a brand-new P50 center?
No. The intent is not to fund brand-new centers. It is specifically designed to support an added, expanded line of work within an already active NIH P50 Center through a revision application.
Who can apply for this opportunity?
Only organizations that already hold an active NIH P50 Center award can apply, because this is a revision mechanism tied to an existing parent P50 award.
What is meant by a "competing revision" in this announcement?
A competing revision, in this context, is a request to add an additional project to an existing P50 Center award in a way that meaningfully broadens the overall scientific scope of the parent award.
What kind of work is NIH expecting to see in the revision?
Applicants are expected to propose an additional project that integrates with, and strengthens, the center as a whole. The revision should be more than a small, marginal add-on and should expand the center's scientific scope in a substantial way.
What is the main scientific focus of PAR-13-298?
The FOA focuses on research to improve the detection of pathogen-induced cancers by studying how carcinogenic pathogens interact with the human microbiome and the host.
What specific research themes are emphasized?
The announcement emphasizes discovery and assessment of molecular signatures that can indicate risk or enable early detection of cancers driven by infectious agents. It also highlights signatures related to chronic inflammation that may contribute to progression from earlier disease states to invasive cancer.
Does the scope include host-pathogen-microbiome interactions?
Yes. The scope spans mechanisms and biomarkers across host-pathogen-microbiome interactions, with a translational emphasis on detection and risk stratification for pathogen-associated malignancies.
What is the translational or practical goal of the research supported?
The practical emphasis is on improving risk stratification and enabling earlier detection of cancers caused by carcinogenic pathogens, including understanding inflammatory signatures that may influence progression toward invasive cancer.
What CFDA program area is this opportunity aligned with?
It is aligned with CFDA 93.394, Cancer Detection and Diagnosis Research.
What NIH funding activity area is listed for this opportunity?
The program is categorized under the NIH funding activity area of Education/Health.
Is cost sharing or matching required?
No. The opportunity does not require cost sharing or matching.
What is the maximum award amount (award ceiling) listed?
The listed award ceiling is $150,000, indicating the revision component is intended to be relatively targeted in budget compared with full center awards while still supporting a meaningful added project.
When was this opportunity posted and created?
The posted date and creation date are both August 6, 2013.
What were the application closing dates?
The original closing date and final closing date were December 11, 2015.
Is this funding opportunity still open for applications?
No. The opportunity is archived and no longer accepting applications. The archive date is January 11, 2016.
Which types of U.S.-based organizations are listed as eligible applicant categories?
Eligible applicant categories include state, county, city/township, special district, and certain housing authorities; public and private institutions of higher education; independent school districts; nonprofit organizations with or without 501(c)(3) status; for-profit organizations other than small businesses; and small businesses.
Are minority-serving institutions specifically mentioned as eligible?
Yes. The FOA explicitly mentions categories such as HBCUs, Hispanic-serving institutions, AANAPISI institutions, Alaska Native and Native Hawaiian Serving Institutions, and tribally controlled colleges and universities as eligible applicant types (subject to the overarching requirement that the applicant already holds an active NIH P50 Center award).
Are tribal governments and tribal organizations included in the eligibility list?
Yes. The FOA lists tribal governments and tribal organizations, including some categories beyond federally recognized tribes.
Are U.S. territories or possessions included as eligible applicants?
Yes. U.S. territories or possessions are explicitly listed among eligible applicant types.
Are faith-based or community-based organizations included?
Yes. Faith-based or community-based organizations are explicitly noted as eligible applicant types (again, within the constraint that only current NIH P50 Center awardees can submit a revision under this announcement).
Are non-U.S. (foreign) organizations eligible to apply?
No. Non-U.S. entities are not eligible to apply under this FOA.
Can a U.S. organization apply if it has a non-U.S. component?
No. Non-U.S. components of U.S. organizations are not eligible under this announcement.
Are foreign components allowed under NIH policy definitions?
No. Foreign components (as defined by NIH policy) are not allowed under this FOA.
Which federal agency provides administrative oversight for this opportunity?
Administrative oversight is through the National Institutes of Health (NIH).
Where does the FOA direct applicants for the full announcement details?
The FOA points applicants to the full announcement on the NIH Grants Guide website.
Who is listed for technical help related to access or linking issues?
The FOA provides NIH Office of Extramural Research (OER) webmaster contacts for access or linking issues.
In plain terms, what is this opportunity best understood as?
It is a focused, time-limited mechanism (now archived) that allowed existing NIH-funded P50 centers to competitively add a new, integrated project aimed at advancing molecular and microbiome-informed approaches for identifying risk and enabling earlier detection of cancers caused by carcinogenic pathogens, particularly where chronic inflammation contributes to progression.
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Previous opportunity: Revisions to P01 Awards for Research on Detection of Pathogen Induced Cancer (DPIC) (P01)
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 13 298) also looked into and applied for these:
| Funding Opportunity |
|---|
| Revision Applications to P01 Awards for Research on Imaging and Biomarkers for Early Cancer Detection (P01) Apply for PAR 13 317 Funding Number: PAR 13 317 Agency: National Institutes of Health Category: Education Health Funding Amount: $150,000 |
| Revision Applications to P50 Awards for Research on Imaging and Biomarkers for Early Cancer Detection (P50) Apply for PAR 13 318 Funding Number: PAR 13 318 Agency: National Institutes of Health Category: Education Health Funding Amount: $150,000 |
| National Cancer Institute Program Project Applications (P01) Apply for PAR 13 321 Funding Number: PAR 13 321 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Increased Knowledge and Innovative Strategies to Reduce HIV IncidenceiKnow Projects (R01) Apply for PAR 13 323 Funding Number: PAR 13 323 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Innovative Molecular Analysis Technology Development for Cancer Research and Clinical Care (SBIR R43/44) Apply for PAR 13 327 Funding Number: PAR 13 327 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Revisions for Early Stage Development of Informatics Technology (P01) Apply for PAR 13 330 Funding Number: PAR 13 330 Agency: National Institutes of Health Category: Education Health Funding Amount: $150,000 |
| Health Promotion Among Racial and Ethnic Minority Males (R21) Apply for PA 13 331 Funding Number: PA 13 331 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Strategic Alliances for Medications Development to Treat Substance Use Disorders (R01) Apply for PAR 13 334 Funding Number: PAR 13 334 Agency: National Institutes of Health Category: Education Health Funding Amount: $3,000,000 |
| Neuroscience Research on Drug Abuse (R21) Apply for PA 13 337 Funding Number: PA 13 337 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Neuroscience Research on Drug Abuse (R03) Apply for PA 13 336 Funding Number: PA 13 336 Agency: National Institutes of Health Category: Education Health Funding Amount: $100,000 |
| Neuroscience Research on Drug Abuse (R01) Apply for PA 13 338 Funding Number: PA 13 338 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Mechanisms of Alcohol and Stimulant Co Addiction (R01) Apply for PA 13 339 Funding Number: PA 13 339 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Mechanisms of Alcohol and Stimulant Co Addiction (R21) Apply for PA 13 340 Funding Number: PA 13 340 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Early Career Award in Chemistry of Drug Abuse and Addiction (ECHEM) (R21/R33) Apply for PAR 13 350 Funding Number: PAR 13 350 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| National Institute on Drug Abuse National Early Warning System (NEWS) Coordinating Center (U01) Apply for RFA DA 14 015 Funding Number: RFA DA 14 015 Agency: National Institutes of Health Category: Education Health Funding Amount: $900,000 |
| Research Answers to NCIs Provocative Questions Group A (R01) Apply for RFA CA 13 016 Funding Number: RFA CA 13 016 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research Answers to NCIs Provocative Questions Group A (R21) Apply for RFA CA 13 017 Funding Number: RFA CA 13 017 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Research Answers to NCIs Provocative Questions Group B (R01) Apply for RFA CA 13 018 Funding Number: RFA CA 13 018 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research Answers to NCIs Provocative Questions Group C (R01) Apply for RFA CA 13 020 Funding Number: RFA CA 13 020 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research Answers to NCIs Provocative Questions Group D (R01) Apply for RFA CA 13 022 Funding Number: RFA CA 13 022 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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