Opportunity Information: Apply for PA 07 082
Apply for PA 07 082
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Risk Factors For Psychopathology Using Existing Data Sets (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Dec 5, 2008 and posted on Nov 22, 2006.
- Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Special district governments Public housing authorities/Indian housing authorities Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts State governments Others (see text field entitled Additional Information on Eligibility for clarification) County governments Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Private institutions of higher education.
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:
The NIH funding opportunity "Risk Factors For Psychopathology Using Existing Data Sets (R01)" (Funding Opportunity Number PA-07-082) supports research that uses existing data to better understand how psychopathology develops over time, including the development of alcohol and drug abuse. The central idea is to encourage investigators to make extensive, creative, and coordinated use of already-collected mental health and substance use research data, with the goal of producing findings that can directly inform the design or improvement of prevention approaches and treatment interventions. Rather than funding new large-scale data collection as the primary activity, the FOA is designed to leverage the scientific value of existing datasets by applying new questions, improved analytic strategies, or integrated analyses that were not previously possible or not previously attempted.
This FOA is jointly issued by three NIH institutes: the National Institute of Mental Health (NIMH), the National Institute on Drug Abuse (NIDA), and the National Institute on Alcohol Abuse and Alcoholism (NIAAA). That joint sponsorship signals that the program is meant to cover a broad range of psychiatric and substance-related outcomes and to encourage work that can connect mental health and substance use trajectories when appropriate. The research focus is on risk factors for psychopathology, meaning applicants are expected to examine predictors, correlates, pathways, or developmental processes that contribute to the onset, persistence, or escalation of mental disorders and/or substance use disorders. The emphasis on development points toward longitudinal thinking (even when using existing data), such as identifying early-life, social, behavioral, biological, or environmental factors that shape later outcomes, clarifying timing and sequencing of risks, and understanding how risk accumulates or interacts across the life course.
Projects funded under this announcement are expected to rely on datasets that are either in a public-use format or privately held by the project director/principal investigator. In practice, this opens the door to analyses of large epidemiologic surveys, cohort studies, clinical trial datasets, administrative or service-use records, archival studies, and other well-characterized resources, as long as the application makes clear that the data exist, are accessible to the research team, and are suitable for the proposed analyses. The phrase "focused and coordinated analyses" also points to work that is not just exploratory, but strategically designed, potentially including harmonization across studies, coordinated analytic plans across multiple datasets, or other approaches that strengthen inference by comparing patterns across samples and settings.
The primary award mechanism for this FOA is the NIH Research Project Grant (R01). That mechanism typically supports substantial, multi-year research projects, which aligns with the expectation of extensive analyses, potentially complex methods, and rigorous, publishable outputs that advance the field. The announcement also notes that applications with related or identical scientific scope may be submitted under the Small Research Grant (R03) mechanism through a separate FOA (PA-06-180), which is relevant for smaller, more targeted analytic efforts or feasibility-oriented work using existing data. In other words, investigators can scale their approach: an R01 for a larger analytic program, or an R03 for a more limited but still impactful study.
Funding levels and the number of awards are not fixed in the announcement. Instead, NIH indicates that award size and duration will vary depending on the nature and scope of the proposed research, and that the total dollars and number of funded projects will depend on the quality of applications received, the requested budgets, and program priorities across the participating institutes. The opportunity is listed as a discretionary grant, with activity categories tied to education and health, and it is associated with CFDA numbers covering mental health research (93.242), alcohol research programs (93.273), and drug abuse and addiction research programs (93.279). There is no cost sharing or matching requirement, which lowers the barrier for applicants that may not have access to non-federal matching funds.
Eligibility is broad and includes many types of domestic and international organizations. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), state and local governments (including counties, cities, townships, special district governments, and independent school districts), tribal governments and tribal organizations, public housing authorities/Indian housing authorities, and other organizations as described in the full announcement. The FOA explicitly states that foreign institutions are eligible to apply, that eligible federal agencies may apply, and that faith-based or community-based organizations may apply, reflecting NIH's generally inclusive approach to institutional eligibility when the scientific and administrative requirements can be met.
The opportunity was originally posted on November 22, 2006, and it used multiple receipt dates rather than a single deadline, meaning applications could be submitted on specified cycles referenced in the full announcement. The listing indicates an archive date of August 5, 2009, which matters for historical context, but the description remains a clear example of NIH priorities around maximizing the value of existing datasets to answer pressing questions about mental illness and substance use risk and development. The full announcement is linked at http://grants.nih.gov/grants/guide/pa-files/PA-07-082.html, and NIH provides an Office of Extramural Research (OER) webmaster contact for access or technical issues with the posting.
Frequently Asked Questions (FAQs)
What is the funding opportunity title and number?
The opportunity is titled "Risk Factors For Psychopathology Using Existing Data Sets (R01)" and the Funding Opportunity Number is PA-07-082.
What is the main purpose of this NIH funding opportunity?
This FOA supports research that uses already-collected data to improve understanding of how psychopathology develops over time, including the development of alcohol and drug abuse. The intent is to generate findings that can directly inform the design or improvement of prevention approaches and treatment interventions.
What kind of research approach is emphasized?
The FOA emphasizes extensive, creative, and coordinated use of existing mental health and substance use datasets. Rather than primarily funding new large-scale data collection, it is designed to leverage the scientific value of existing datasets by applying new questions, improved analytic strategies, or integrated analyses that were not previously possible or not previously attempted.
Which NIH institutes jointly issued this announcement?
This FOA is jointly issued by the National Institute of Mental Health (NIMH), the National Institute on Drug Abuse (NIDA), and the National Institute on Alcohol Abuse and Alcoholism (NIAAA).
What scientific topics and outcomes are in scope?
The scope covers a broad range of psychiatric and substance-related outcomes. Applicants are expected to examine risk factors for psychopathology, including predictors, correlates, pathways, or developmental processes that contribute to the onset, persistence, or escalation of mental disorders and/or substance use disorders.
Does the FOA favor developmental or longitudinal perspectives?
Yes. The emphasis on development points toward longitudinal thinking even when using existing data, such as identifying early-life, social, behavioral, biological, or environmental factors that shape later outcomes; clarifying timing and sequencing of risks; and understanding how risk accumulates or interacts across the life course.
Are applicants expected to collect new data?
No. The FOA is designed to prioritize analysis of existing datasets. It specifically encourages leveraging already-collected data rather than proposing new large-scale data collection as the primary activity.
What types of datasets can be used?
Projects are expected to rely on datasets that are either in a public-use format or privately held by the project director/principal investigator. Examples mentioned include large epidemiologic surveys, cohort studies, clinical trial datasets, administrative or service-use records, archival studies, and other well-characterized resources.
What does NIH mean by "focused and coordinated analyses"?
The FOA points toward work that is strategically designed and not purely exploratory. Examples described include harmonization across studies, coordinated analytic plans across multiple datasets, and other approaches that strengthen inference by comparing patterns across samples and settings.
What is the primary award mechanism?
The primary award mechanism is the NIH Research Project Grant (R01), which typically supports substantial, multi-year research projects and aligns with expectations for extensive analyses, complex methods, and rigorous publishable outputs.
Is there an option for a smaller project mechanism?
Yes. The announcement notes that applications with related or identical scientific scope may also be submitted under the Small Research Grant (R03) mechanism through a separate FOA (PA-06-180), which may be more suitable for smaller, targeted, or feasibility-oriented analytic efforts using existing data.
Are funding levels or the number of awards specified?
No. Funding levels and the number of awards are not fixed. NIH indicates award size and duration will vary depending on the nature and scope of the proposed research, and the total dollars and number of funded projects will depend on application quality, requested budgets, and program priorities across the participating institutes.
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement.
What are the related CFDA numbers for this opportunity?
The opportunity is associated with CFDA numbers 93.242 (mental health research), 93.273 (alcohol research programs), and 93.279 (drug abuse and addiction research programs).
What activity categories are associated with the grant listing?
The listing describes the opportunity as a discretionary grant, with activity categories tied to education and health.
Who is eligible to apply?
Eligibility is broad and includes many domestic and international organization types. Eligible applicants include public and private institutions of higher education; nonprofit organizations (with and without 501(c)(3) status); for-profit organizations (including small businesses); state and local governments (including counties, cities, townships, special district governments, and independent school districts); tribal governments and tribal organizations; public housing authorities/Indian housing authorities; and other organizations as described in the full announcement.
Are foreign institutions eligible?
Yes. The FOA explicitly states that foreign institutions are eligible to apply.
Can federal agencies apply?
Yes. The FOA states that eligible federal agencies may apply.
Are faith-based or community-based organizations eligible?
Yes. The FOA indicates that faith-based or community-based organizations may apply.
What does the FOA require regarding data access and availability?
The application should make clear that the data already exist, are accessible to the research team, and are suitable for the proposed analyses. Datasets may be public-use or privately held by the project director/principal investigator, but accessibility and suitability need to be addressed.
Is this opportunity still active?
The listing shows the opportunity was originally posted on November 22, 2006 and indicates an archive date of August 5, 2009. The FOA text remains useful for understanding NIH priorities described in the announcement, but the archive date is important context for current submission status.
Was there a single deadline or multiple receipt dates?
The opportunity used multiple receipt dates rather than a single deadline, meaning applications could be submitted on specified cycles referenced in the full announcement.
Where can the full announcement be found?
The full announcement is linked at http://grants.nih.gov/grants/guide/pa-files/PA-07-082.html.
Who should be contacted for access or technical issues with the posting?
NIH provides an Office of Extramural Research (OER) webmaster contact for access or technical issues with the posting.
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| Functional Genetics And Genomics Of Drug Addiction (R03) Apply for PA 07 168 Funding Number: PA 07 168 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Functional Genetics and Genomics of Drug Addiction (R21) Apply for PA 07 167 Funding Number: PA 07 167 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
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| Memory T Lymphocytes in Cancer Immunology (R01) Apply for PA 07 255 Funding Number: PA 07 255 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Cancer Surveillance Using Health Claims Based Data (R01) Apply for PA 07 254 Funding Number: PA 07 254 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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| Epigenetic Approaches in Cancer Epidemiology (R21) Apply for PA 07 299 Funding Number: PA 07 299 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
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