Opportunity Information: Apply for PA 09 265

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Secondary Analyses of Existing Data Sets and Stored Biospecimens to Address Clinical Aging Research Questions (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
  • This funding opportunity was created on Sep 29, 2009 and posted on Sep 29, 2009.
  • Applicants must submit their applications by Jan 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Small businesses State governments Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Independent school districts Special district governments City or township governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The National Institute on Aging (NIA), part of the National Institutes of Health, offered this R01 funding opportunity (PA-09-265) to support short-term research projects that rely on secondary analyses rather than new data collection. The central goal is to use already-existing resources, such as established clinical or epidemiologic data sets and stored human biospecimens, to answer clinically focused questions about aging. That includes studying age-related changes that affect health across the life span, as well as diseases, conditions, and disabilities that are especially relevant to older adults.

The program is geared toward projects with clear, testable hypotheses in clinical aging research. Applicants are expected to use the existing data or specimens to generate findings that can directly improve understanding of health and disease in aging populations and, ideally, help shape real-world decisions. The FOA also emphasizes practical downstream value: results can be used to inform the design and implementation of future epidemiologic studies or human intervention trials, and to strengthen geriatric practice related to maintaining health, managing chronic disease, and preventing disability. In addition to hypothesis-driven clinical questions, the announcement explicitly allows the use of existing data sets to develop and evaluate new statistical or analytic methods, as long as those methods are meaningfully tied to clinical aging research.

This opportunity uses the standard NIH Research Project Grant (R01) mechanism. Budgets and project durations are not fixed because the NIA anticipated wide variation in the scope of proposed secondary analyses. There was no set-aside amount published; instead, the total dollars awarded and the number of funded projects depended on the scientific merit of applications and the availability of funds in NIA's general funding pool. In practice, that means awards could differ substantially in size and length, and competition would be based heavily on rigor, feasibility, and significance given the constraints and strengths of the existing data or biospecimen resource being analyzed.

A notable feature is that applicants could include costs for archiving data for public availability, but only when those archiving activities are directly connected to the proposed secondary analyses. This signals an expectation that researchers not only analyze existing resources effectively but may also contribute to broader scientific value by preparing data products for sharing, when appropriate and justified.

Eligibility was broad, spanning many organization types. Eligible applicants included public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (including small businesses), state and local governments, independent school districts, special district governments, public housing authorities/Indian housing authorities, and tribal governments and tribal organizations. The FOA also explicitly included a range of additional eligible entities such as historically Black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and even non-U.S. (foreign) organizations, along with eligible federal agencies. Cost sharing or matching was not required.

Key administrative details from the listing include: the opportunity category is discretionary; the funding instrument is a grant; the activity category is health; and it is associated with CFDA 93.866 (Aging Research). The announcement was posted on September 29, 2009, and the final closing date was January 7, 2013, with an archive date of February 7, 2013. The full announcement was hosted through the NIH Grants Guide (the link in the source points to the NIH page for PA-09-265), and the NIH Office of Extramural Research webmaster contact was provided for access or linking issues.

Frequently Asked Questions (FAQs)

What is this funding opportunity?

This is a National Institute on Aging (NIA), National Institutes of Health (NIH) R01 funding opportunity announcement (FOA) identified as PA-09-265. It supports short-term research projects in clinical aging research that rely on secondary analyses rather than collecting new data.

What is the main purpose of PA-09-265?

The main purpose is to support hypothesis-driven clinical aging research using already-existing resources (for example, established clinical or epidemiologic data sets and stored human biospecimens) to answer clinically focused questions about aging, age-related changes, and conditions particularly relevant to older adults.

Does this FOA support new data collection?

No. The FOA is intended for projects that rely on secondary analyses and existing resources, rather than new data collection.

What kinds of resources can be used in the proposed research?

The FOA highlights using existing clinical or epidemiologic data sets and stored human biospecimens as the core resources for the proposed secondary analyses.

What research topics are considered responsive?

Responsive topics include clinically focused questions about aging, including age-related changes affecting health across the life span, as well as diseases, conditions, and disabilities that are especially relevant to older adults.

Is the research expected to be hypothesis-driven?

Yes. The program is geared toward projects with clear, testable hypotheses in clinical aging research.

What type of impact is the NIA looking for from funded projects?

The FOA emphasizes generating findings that improve understanding of health and disease in aging populations and, ideally, help shape real-world decisions. It also highlights practical downstream value, such as informing the design and implementation of future epidemiologic studies or human intervention trials and strengthening geriatric practice.

Are methods development projects allowed?

Yes. The FOA explicitly allows the use of existing data sets to develop and evaluate new statistical or analytic methods, as long as those methods are meaningfully tied to clinical aging research.

What funding mechanism is used?

This opportunity uses the standard NIH Research Project Grant (R01) mechanism.

Are budget amounts and project durations fixed?

No. Budgets and project durations are not fixed. The NIA anticipated wide variation in the scope of proposed secondary analyses, so awards could differ substantially in size and length.

Is there a set-aside amount for this FOA?

No set-aside amount was published. The total dollars awarded and the number of funded projects depended on the scientific merit of applications and the availability of funds in NIA's general funding pool.

How competitive is this opportunity expected to be?

Based on the FOA description, competition would be strongly influenced by scientific merit, rigor, feasibility, and significance, taking into account the constraints and strengths of the existing data set or biospecimen resource being analyzed.

Can applicants include costs for data archiving and public availability?

Yes, applicants could include costs for archiving data for public availability, but only when the archiving activities are directly connected to the proposed secondary analyses.

What does the FOA suggest about data sharing expectations?

It suggests that, when appropriate and justified, researchers may contribute broader scientific value by preparing data products for sharing, specifically when those archiving efforts are directly tied to the proposed secondary analyses.

Who is eligible to apply?

Eligibility is broad and includes many organization types, such as public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (including small businesses), and various government entities.

Are tribal governments and tribal organizations eligible?

Yes. Tribal governments and tribal organizations are explicitly listed as eligible applicants.

Are minority-serving institutions eligible?

Yes. The FOA explicitly includes historically Black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), and Alaska Native and Native Hawaiian-serving institutions as eligible entities.

Are faith-based or community-based organizations eligible?

Yes. Faith-based or community-based organizations are included among the eligible entities.

Can non-U.S. (foreign) organizations apply?

Yes. The FOA explicitly includes non-U.S. (foreign) organizations as eligible applicants.

Are U.S. territories or possessions eligible?

Yes. U.S. territories or possessions are listed among the eligible entities.

Are federal agencies eligible to apply?

Yes. Eligible federal agencies are included in the eligibility list.

Is cost sharing or matching required?

No. Cost sharing or matching was not required.

What is the opportunity category and funding instrument?

The opportunity category is discretionary, and the funding instrument is a grant.

What is the activity category?

The activity category is health.

What CFDA number is associated with this opportunity?

This FOA is associated with CFDA 93.866 (Aging Research).

When was the announcement posted and when did it close?

The announcement was posted on September 29, 2009. The final closing date was January 7, 2013, and the archive date was February 7, 2013.

Where was the full announcement posted?

The full announcement was hosted through the NIH Grants Guide on the NIH page for PA-09-265.

Who was listed as the contact for access or linking issues?

The NIH Office of Extramural Research webmaster contact was provided for access or linking issues related to the announcement listing.

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