Opportunity Information: Apply for RFA OD 11 003
Apply for RFA OD 11 003
- The National Institutes of Health in the education food and nutrition health income security and social services sector is offering a public funding opportunity titled "Specialized Centers of Research (SCOR) on Sex Differences (P50)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.103 Food and Drug AdministrationResearch 93.242 Mental Health Research Grants 93.279 Drug Abuse and Addiction Research Programs 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
- This funding opportunity was created on Jul 20, 2011 and posted on Jun 28, 2011.
- Applicants must submit their applications by Oct 4, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $9,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- The number of recipients for this funding is limited to 9 candidate(s).
- Eligible applicants include: Independent school districts Special district governments City or township governments Private institutions of higher education For profit organizations other than small businesses State governments Public housing authorities/Indian housing authorities County governments Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Organizations) are not eligible to apply. Foreign (non U.S.) components of U.S. Organizations are not allowed.
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Opportunity Summary:
The Specialized Centers of Research (SCOR) on Sex Differences (P50) funding opportunity (RFA-OD-11-003) was a National Institutes of Health (NIH) discretionary grant program led by the NIH Office of Research on Women's Health (ORWH) in partnership with participating NIH organizations and institutes. Its main purpose was to expand the SCOR network by supporting interdisciplinary research centers focused on sex differences research, with a clear emphasis on building integrated programs that connect basic science and clinical research. In practice, this meant proposing a coordinated center-level research agenda that could explain and address how biological sex and related factors influence health and disease, especially for conditions that affect women, while also ensuring that findings could move back and forth between mechanistic studies and patient-oriented research.
A key feature of the announcement was the expectation that each awarded center would function as a hub for collaboration across disciplines rather than as a collection of disconnected projects. The intent was to create an environment where investigators from different scientific and clinical backgrounds could work together on a shared health theme, develop common methods and resources, and accelerate progress on questions that are difficult to solve within a single lab or department. The centers were expected to advance understanding of sex differences in health outcomes, disease mechanisms, prevention, diagnosis, and treatment, and to do so in a way that meaningfully bridges the gap between foundational biology and real-world clinical care.
The opportunity used the NIH P50 Specialized Center mechanism, which is designed for multi-project, multidisciplinary center grants. While the full structure requirements are detailed in the official announcement, the general expectation for a P50 is a coordinated program with multiple related research components, often supported by shared resources or cores, under a single overarching theme and leadership plan. This mechanism is typically used when the research problem benefits from tight coordination, shared infrastructure, and sustained collaboration across projects.
Funding for the program was estimated at $9,000,000 total, with an award ceiling of $750,000. NIH expected to make about 9 awards. The solicitation was posted June 28, 2011, with an original and current closing date of October 4, 2011, and it was archived November 4, 2011. There was no cost-sharing or matching requirement, which is consistent with many NIH research grant programs.
Eligible applicants were broad and included many types of U.S.-based organizations, spanning public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) entities), state and local governments, tribal governments and tribal organizations, school districts, special district governments, public housing authorities/Indian housing authorities, and for-profit organizations other than small businesses, as well as small businesses. The eligibility notes also explicitly included a range of designated institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribal Colleges and Universities (including tribally controlled institutions), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations, along with U.S. territories or possessions and eligible federal agencies. At the same time, the announcement made clear that non-U.S. entities (foreign organizations) were not eligible to apply, and foreign components of U.S. organizations were not allowed, keeping the supported work fully within allowable domestic NIH project boundaries for this competition.
The opportunity was associated with multiple CFDA numbers tied to research areas across NIH and related agencies, reflecting the cross-cutting nature of sex differences research and the fact that many health topics could fit under this umbrella. Those CFDA listings included FDA Research (93.103), Mental Health Research Grants (93.242), Drug Abuse and Addiction Research Programs (93.279), Arthritis and Musculoskeletal and Skin Diseases Research (93.846), Diabetes, Digestive, and Kidney Diseases Extramural Research (93.847), Child Health and Human Development Extramural Research (93.865), and Aging Research (93.866). This breadth signals that applications could address diverse disease areas and life stages, as long as the central focus remained on sex differences and the proposed center integrated basic and clinical work on a health issue affecting women.
For applicants seeking the original details, the NIH provided an official guide notice link (http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-11-003.html). For access or technical issues with the announcement, the listed support contact was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: Specialized Centers of Research (SCOR) on Sex Differences (P50) - RFA-OD-11-003
What is the SCOR on Sex Differences (P50) funding opportunity?
The Specialized Centers of Research (SCOR) on Sex Differences (P50) opportunity (RFA-OD-11-003) was an NIH discretionary grant program led by the NIH Office of Research on Women's Health (ORWH) in partnership with participating NIH organizations and institutes. It supported interdisciplinary research centers focused on sex differences research using the NIH P50 Specialized Center grant mechanism.
What was the main purpose of this program?
The main purpose was to expand the SCOR network by funding coordinated, interdisciplinary research centers that focus on sex differences in health and disease, with a clear emphasis on building integrated programs that connect basic science and clinical research.
What does "sex differences research" mean in the context of this opportunity?
Within this announcement, sex differences research referred to research intended to explain and address how biological sex and related factors influence health and disease. The program emphasized conditions that affect women, while also expecting research to move between mechanistic (basic) studies and patient-oriented (clinical) research.
What kind of grant mechanism was used (P50), and what does that imply?
This opportunity used the NIH P50 Specialized Center mechanism, which is designed for multi-project, multidisciplinary center grants. In general, a P50 is expected to support a coordinated program with multiple related research components, often supported by shared resources or cores, all organized under one overarching theme and a center-level leadership and management plan.
What was a defining feature of how an awarded center was expected to function?
A key expectation was that each awarded center would serve as a hub for collaboration across disciplines rather than as a collection of disconnected projects. The intent was to create an environment where investigators from different scientific and clinical backgrounds work together on a shared health theme, develop common methods and resources, and accelerate progress on complex questions.
What scientific scope and outcomes were centers expected to advance?
Centers were expected to advance understanding of sex differences in health outcomes and in multiple stages of health and disease, including mechanisms, prevention, diagnosis, and treatment. A central emphasis was on bridging foundational biology and real-world clinical care in a meaningful and integrated way.
Was the program focused only on basic science or only on clinical research?
No. The program emphasized integrated programs connecting basic science and clinical research, with the expectation that findings could move back and forth between mechanistic studies and patient-oriented research.
How much total funding was estimated for the program?
Total estimated funding was $9,000,000.
What was the award ceiling for an individual award?
The award ceiling was $750,000.
How many awards did NIH expect to make?
NIH expected to make about 9 awards.
When was the solicitation posted, and what were the key dates?
The solicitation was posted on June 28, 2011. The original and current closing date was October 4, 2011. The opportunity was archived on November 4, 2011.
Is this funding opportunity still open?
No. Based on the provided dates, it closed on October 4, 2011 and was archived on November 4, 2011.
Was there a cost-sharing or matching requirement?
No. The announcement specified that there was no cost-sharing or matching requirement.
Who was eligible to apply?
Eligibility was broad and included many types of U.S.-based organizations, including public and private institutions of higher education; nonprofits (including 501(c)(3) and certain non-501(c)(3) organizations); state and local governments; tribal governments and tribal organizations; school districts; special district governments; public housing authorities/Indian housing authorities; for-profit organizations other than small businesses; and small businesses.
Were specific institution types explicitly included as eligible?
Yes. The eligibility notes explicitly included designated institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribal Colleges and Universities (including tribally controlled institutions), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations. U.S. territories or possessions and eligible federal agencies were also included.
Were non-U.S. (foreign) organizations eligible to apply?
No. The announcement stated that non-U.S. entities (foreign organizations) were not eligible to apply.
Were foreign components of U.S. organizations allowed?
No. The announcement stated that foreign components of U.S. organizations were not allowed for this competition.
What types of research topics could fit under this opportunity?
The program was cross-cutting and could encompass diverse disease areas and life stages, as reflected by the multiple CFDA numbers associated with NIH and related agencies. However, applications were expected to maintain a central focus on sex differences and propose an integrated center that connects basic and clinical work on a health issue affecting women.
Which CFDA numbers were associated with this opportunity?
The opportunity listed multiple CFDA numbers, including FDA Research (93.103), Mental Health Research Grants (93.242), Drug Abuse and Addiction Research Programs (93.279), Arthritis and Musculoskeletal and Skin Diseases Research (93.846), Diabetes, Digestive, and Kidney Diseases Extramural Research (93.847), Child Health and Human Development Extramural Research (93.865), and Aging Research (93.866).
What do the multiple CFDA numbers indicate about the program?
The multiple CFDA listings reflect the cross-cutting nature of sex differences research and suggest that many health topics could fit within the program, so long as the central theme remained sex differences and the proposed work integrated basic and clinical research.
Where can applicants find the official announcement details?
The official NIH guide notice link provided was: http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-11-003.html
Who was listed as the support contact for access or technical issues?
For access or technical issues with the announcement, the listed support contact was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What did NIH want to avoid in proposed centers?
Based on the stated expectations, NIH wanted centers to be more than a set of disconnected projects. The intent was a coordinated, center-level research agenda with active collaboration, shared approaches, and integrated basic and clinical components under a common theme.
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