Opportunity Information: Apply for PA 10 242
Apply for PA 10 242
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Structural Interventions, Alcohol Use, and Risk of HIV/AIDS (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
- This funding opportunity was created on Aug 2, 2010 and posted on Aug 2, 2010.
- Applicants must submit their applications by May 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Native American tribal governments (Federally recognized) For profit organizations other than small businesses Small businesses City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities County governments State governments Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Structural Interventions, Alcohol Use, and Risk of HIV/AIDS (R01) funding opportunity (PA-10-242) is a National Institutes of Health grant announcement led by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). It supports R01 research projects that test whether structural interventions can lower HIV/AIDS transmission risk by changing the broader conditions in which alcohol is used. The central idea is that alcohol use often affects HIV risk through its surrounding environment, such as where drinking happens, what policies govern alcohol availability, and what community or institutional factors shape intoxication, sexual behavior, and access to prevention services. While structural and environmental strategies have been used effectively to reduce other alcohol-related harms, the announcement emphasizes that far less work has examined these approaches specifically for HIV/AIDS risk reduction, creating a clear research gap this program is meant to address.
The focus is on interventions that operate beyond the individual level, meaning projects are expected to look at changes in settings, systems, policies, or community-level conditions rather than only counseling or education aimed at a single person. In practice, this can include evaluating policy changes, programmatic shifts in venues or organizations, or community and institutional modifications that influence how, when, and where alcohol is consumed, and how those patterns intersect with behaviors and circumstances that elevate HIV risk. The overall goal is to produce evidence on what works, under what conditions, and for which populations, when the environment of alcohol use is altered in ways intended to reduce HIV exposure and transmission.
This opportunity uses the NIH R01 mechanism, which is typically intended for more mature, substantial research projects with clear hypotheses, strong designs, and the ability to generate rigorous findings. The announcement also notes that it runs in parallel with a separate but scientifically identical opportunity that uses the R21 mechanism (PA-10-243), which generally supports earlier-stage or exploratory work. Applicants choosing PA-10-242 should be prepared to propose an R01-appropriate scope, including a well-developed study plan, analytic approach, and a justification for the scale and duration of the work.
Funding amounts, project size, project period, and the number of awards are not fixed in advance. Instead, they are expected to vary depending on the scientific goals and real-world requirements of each proposed project. NIAAA indicates that the total dollars awarded and the number of grants ultimately made will depend on the volume of applications received, their overall quality, the proposed durations, and the requested budgets and costs, consistent with NIH peer review and institute funding decisions. There is no cost sharing or matching requirement for applicants.
Eligibility is broad and includes many types of U.S. and non-U.S. organizations. Eligible applicants include public and private institutions of higher education; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (including small businesses and other for-profits); local, county, state, and tribal governments; public housing authorities/Indian housing authorities; independent school districts; and special district governments. The eligibility language also explicitly includes a range of mission- or population-focused institutions and entities such as Historically Black Colleges and Universities, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, regional organizations, U.S. territories or possessions, and foreign (non-U.S.) entities.
Key administrative details show that the opportunity falls under CFDA 93.273 (Alcohol Research Programs) and is categorized as a discretionary health research grant. The announcement was posted on August 2, 2010, and the final closing date for submissions was May 7, 2013, with an archive date of June 7, 2013, meaning it is no longer accepting applications as an active opportunity. The full announcement is referenced at the NIH Grants Guide page (http://grants.nih.gov/grants/guide/pa-files/PA-10-242.html). For technical issues accessing the notice or linking to it, the contact provided is the NIH Office of Extramural Research webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
What is the title and number of this funding opportunity?
The opportunity is titled Structural Interventions, Alcohol Use, and Risk of HIV/AIDS (R01) and is identified as PA-10-242.
Which agency and institute lead this grant announcement?
This is a National Institutes of Health (NIH) grant announcement led by the National Institute on Alcohol Abuse and Alcoholism (NIAAA).
What type of grant mechanism does this opportunity use?
This opportunity uses the NIH R01 mechanism, which is generally intended for more mature, substantial research projects with clear hypotheses and rigorous study designs.
What is the core research goal of PA-10-242?
The goal is to support research projects that test whether structural interventions can reduce HIV/AIDS transmission risk by changing the broader conditions in which alcohol is used (for example, settings, systems, policies, or community-level factors).
What does the announcement mean by "structural interventions"?
Based on the description provided, structural interventions are approaches that operate beyond the individual level and instead focus on changing settings, systems, policies, or community/institutional conditions that shape alcohol use and the related circumstances that can increase HIV risk.
What kinds of environmental or contextual factors are emphasized?
The announcement highlights that alcohol use can influence HIV risk through the surrounding environment, including where drinking occurs, policies affecting alcohol availability, and community or institutional factors that shape intoxication, sexual behavior, and access to prevention services.
Is the program focused on individual counseling or education interventions?
No. The focus is on interventions that work beyond the individual level. Projects are expected to examine changes in broader conditions (such as policies, venues, organizations, or community institutions), rather than only one-on-one counseling or education targeted to a single person.
What types of interventions might be responsive to this announcement?
Examples implied by the description include evaluating policy changes, programmatic shifts within venues or organizations, or community and institutional modifications that influence how, when, and where alcohol is consumed and how those patterns intersect with HIV exposure and transmission risk.
What research gap is this opportunity intended to address?
The announcement notes that structural and environmental strategies have been used effectively to reduce other alcohol-related harms, but that far less work has examined these approaches specifically for HIV/AIDS risk reduction. This gap is a central rationale for the program.
What kind of evidence is the program trying to generate?
The overall objective is to produce evidence about what works, under what conditions, and for which populations when the environment of alcohol use is altered to reduce HIV exposure and transmission.
Is there a related NIH opportunity using a different mechanism?
Yes. The announcement states it runs in parallel with a scientifically identical opportunity using the R21 mechanism (PA-10-243), which typically supports earlier-stage or exploratory work.
How should an applicant decide between this R01 (PA-10-242) and the related R21 (PA-10-243)?
Based on the description provided, applicants choosing PA-10-242 should be prepared to propose an R01-appropriate scope, including a well-developed study plan, analytic approach, and a justification for the scale and duration of the work. The R21 is described as generally supporting more exploratory efforts.
Are the funding amount and number of awards predetermined?
No. Funding amounts, project size, project period, and the number of awards are not fixed in advance and are expected to vary based on scientific goals and real-world requirements of each project.
What factors determine how many awards are made and how much funding is provided?
NIAAA indicates that total dollars awarded and the number of grants will depend on the volume of applications, their overall quality, the proposed durations, and the requested budgets and costs, consistent with NIH peer review and institute funding decisions.
Is cost sharing or matching required?
No. The announcement states there is no cost sharing or matching requirement for applicants.
Who is eligible to apply?
Eligibility is broad and includes many U.S. and non-U.S. organization types, including: public and private institutions of higher education; nonprofit organizations (with or without 501(c)(3) status); for-profit organizations (including small businesses); local, county, state, tribal, and special district governments; public housing authorities/Indian housing authorities; independent school districts; U.S. territories or possessions; and foreign (non-U.S.) entities.
Are minority-serving institutions and community-based organizations included in eligibility?
Yes. The eligibility language explicitly includes entities such as Historically Black Colleges and Universities, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, as well as faith-based and community-based organizations, and regional organizations.
What is the CFDA number associated with this opportunity?
The opportunity falls under CFDA 93.273, listed as Alcohol Research Programs.
How is this opportunity categorized?
It is categorized as a discretionary health research grant.
Is this funding opportunity still accepting applications?
No. The announcement lists a final closing date of May 7, 2013 and an archive date of June 7, 2013, indicating it is no longer active for new submissions.
When was the opportunity originally posted?
The announcement was posted on August 2, 2010.
Where can the full funding announcement be found?
The full announcement is referenced at the NIH Grants Guide page: http://grants.nih.gov/grants/guide/pa-files/PA-10-242.html.
Who should be contacted for technical issues accessing the notice or linking to it?
For technical issues accessing the notice or linking to it, the contact provided is the NIH Office of Extramural Research webmaster: FBOWebmaster@OD.NIH.GOV.
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