Opportunity Information: Apply for PA 11 053
Apply for PA 11 053
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Studies in Neonatal Hypoglycemia (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Dec 2, 2010 and posted on Dec 2, 2010.
- Applicants must submit their applications by May 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: For profit organizations other than small businesses County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Native American tribal governments (Federally recognized) Special district governments Private institutions of higher education Independent school districts State governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Studies in Neonatal Hypoglycemia (R01) opportunity (Funding Opportunity Number PA-11-053) is a National Institutes of Health grant announcement led by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). Its main goal is to support research that improves understanding of neonatal hypoglycemia and, more broadly, altered glucose homeostasis in newborns. The announcement emphasizes that, even though research has clarified many causes and biological mechanisms behind abnormal glucose regulation in the neonatal period, important knowledge gaps still limit how well clinicians can monitor, prevent, and treat these problems. NICHD is using this program to encourage projects that can close those gaps and ultimately inform better clinical approaches to detecting and managing low blood glucose in newborns.
The scientific scope is intentionally broad and includes basic, applied, and translational research. In practice, that means projects can range from fundamental studies of physiology and mechanisms (for example, pathways involved in neonatal glucose production and utilization, hormonal regulation, metabolic adaptation after birth, and disease-related disruptions) to applied or translational work that connects discoveries to clinical tools and decision-making. The FOA frames the desired impact in terms of improved monitoring and treatment strategies for altered neonatal glucose homeostasis, which can include refining how hypoglycemia is identified, determining which infants are at greatest risk, understanding short- and long-term consequences, and improving intervention strategies.
The funding mechanism is the NIH Research Project Grant (R01), which is typically used for substantial, hypothesis-driven projects with a defined research plan. This FOA is part of a set of parallel announcements with the same scientific focus but different grant mechanisms: PA-11-054 supports the smaller-scope R03 mechanism, and PA-11-055 supports the exploratory/developmental R21 mechanism. Applicants who have smaller, pilot-style aims or early-stage concepts might consider those companion FOAs, while PA-11-053 is aimed at full R01-level research programs.
Award size, project period, and the number of awards were not fixed in advance. NICHD indicated that budgets and durations would vary depending on the nature and scope of the proposed work, and that total funding and award counts would ultimately depend on the number of applications received, their scientific merit, their requested costs, and their proposed durations. There is no cost sharing or matching requirement listed for this opportunity.
Eligibility is broad and includes a wide range of domestic and non-domestic organizations. Eligible applicants include for-profit organizations (other than small businesses), small businesses, nonprofit organizations (including those with and without 501(c)(3) status), public and private institutions of higher education, and multiple levels of government (state governments, county governments, city or township governments, special district governments, and independent school districts). The eligibility list also includes public housing authorities/Indian housing authorities and other categories as clarified in the FOA. Additional eligible groups specifically called out include federally recognized Native American tribal governments, other tribal organizations, Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, U.S. territories or possessions, regional organizations, eligible agencies of the federal government, and foreign organizations (non-U.S. entities).
Key administrative details reflect that this was a discretionary grant opportunity in the Health category (CFDA 93.865, Child Health and Human Development Extramural Research). The FOA was posted on December 2, 2010, with an original and final closing date of May 7, 2014, and it was archived on June 7, 2014. The full announcement was hosted through the NIH Grants Guide at the link provided in the notice. For technical issues accessing the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster (FBOWebmaster@OD.NIH.GOV).
Frequently Asked Questions (FAQs): Studies in Neonatal Hypoglycemia (R01) - PA-11-053
What is the Studies in Neonatal Hypoglycemia (R01) funding opportunity?
Studies in Neonatal Hypoglycemia (R01) (Funding Opportunity Number PA-11-053) is a National Institutes of Health (NIH) grant announcement led by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). It supports research aimed at improving understanding of neonatal hypoglycemia and, more broadly, altered glucose homeostasis in newborns.
Which NIH institute leads this opportunity?
This opportunity is led by NICHD (Eunice Kennedy Shriver National Institute of Child Health and Human Development).
What is the main goal of PA-11-053?
The main goal is to support research that closes key knowledge gaps that currently limit how well clinicians can monitor, prevent, and treat neonatal hypoglycemia and other abnormalities in neonatal glucose regulation. The intended impact is to inform better clinical approaches to detecting and managing low blood glucose in newborns.
What research areas and topics are within the scope of this FOA?
The scientific scope is intentionally broad and includes basic, applied, and translational research focused on neonatal hypoglycemia and altered glucose homeostasis in newborns.
Does the FOA support basic science research?
Yes. The FOA includes basic research such as fundamental studies of physiology and mechanisms related to neonatal glucose production and utilization, hormonal regulation, metabolic adaptation after birth, and disease-related disruptions of glucose regulation.
Does the FOA support translational or clinically oriented research?
Yes. The FOA also supports applied and translational work that connects discoveries to clinical tools and decision-making, with an emphasis on improving monitoring and treatment strategies for altered neonatal glucose homeostasis.
What kinds of clinical or health impacts does NICHD want this research to enable?
The FOA frames the desired impact as improving strategies for monitoring and treating altered neonatal glucose homeostasis. Examples described include refining how hypoglycemia is identified, determining which infants are at greatest risk, understanding short- and long-term consequences, and improving intervention strategies.
What funding mechanism is used for PA-11-053?
PA-11-053 uses the NIH Research Project Grant (R01) mechanism, which is typically used for substantial, hypothesis-driven projects with a defined research plan.
Are there related or companion funding opportunities with the same scientific focus?
Yes. This FOA is part of a set of parallel announcements with the same scientific focus but different grant mechanisms: PA-11-054 supports the R03 mechanism (smaller scope), and PA-11-055 supports the R21 mechanism (exploratory/developmental).
When should an applicant consider the R03 or R21 companion FOAs instead of the R01?
Based on the announcement description, applicants with smaller, pilot-style aims or early-stage concepts may consider the companion FOAs (PA-11-054 for R03 and PA-11-055 for R21), while PA-11-053 is aimed at full R01-level research programs.
Is the award size fixed?
No. NICHD indicated that award budgets would vary depending on the nature and scope of the proposed work.
Is the project period (duration) fixed?
No. Project durations were not fixed in advance and were expected to vary depending on the proposed work.
Is there a fixed number of awards?
No. The number of awards was not fixed in advance. NICHD stated that total funding and award counts would depend on factors such as the number of applications received, their scientific merit, requested costs, and proposed durations.
Is cost sharing or matching required?
No. There is no cost sharing or matching requirement listed for this opportunity.
Who is eligible to apply?
Eligibility is broad and includes a wide range of domestic and non-domestic organizations. Eligible applicants include for-profit organizations (other than small businesses), small businesses, nonprofit organizations (including those with and without 501(c)(3) status), public and private institutions of higher education, and multiple levels of government (including state, county, city or township, special district governments, and independent school districts).
Are U.S. tribal organizations and tribal governments eligible?
Yes. The FOA specifically calls out eligibility for federally recognized Native American tribal governments and other tribal organizations, among other categories.
Are minority-serving institutions eligible to apply?
Yes. The FOA specifically mentions Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs) as eligible.
Are faith-based or community-based organizations eligible?
Yes. The FOA includes faith-based or community-based organizations among eligible applicants.
Are U.S. territories or possessions eligible?
Yes. The FOA includes U.S. territories or possessions among eligible applicants.
Are foreign (non-U.S.) organizations eligible to apply?
Yes. The FOA states that foreign organizations (non-U.S. entities) are eligible.
Is this a discretionary grant, and what category does it fall under?
Yes. This was described as a discretionary grant opportunity in the Health category.
What is the CFDA number for this opportunity?
The CFDA number listed is 93.865, described as Child Health and Human Development Extramural Research.
When was the FOA posted?
The FOA was posted on December 2, 2010.
What were the closing dates for the opportunity?
The original and final closing date listed for the FOA was May 7, 2014.
Is this funding opportunity still open?
No. The FOA was archived on June 7, 2014, and the final closing date was May 7, 2014.
Where was the full announcement posted?
The full announcement was hosted through the NIH Grants Guide at the link provided in the notice.
Who should be contacted for technical issues accessing the announcement?
For technical issues accessing the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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