Opportunity Information: Apply for PA 11 054
Apply for PA 11 054
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Studies in Neonatal Hypoglycemia (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Dec 2, 2010 and posted on Dec 2, 2010.
- Applicants must submit their applications by May 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Special district governments City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities County governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses State governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Studies in Neonatal Hypoglycemia (R03) opportunity (Funding Opportunity Number PA-11-054) is a National Institutes of Health grant announcement issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). It focuses specifically on neonatal hypoglycemia and, more broadly, the biology and clinical realities of altered neonatal glucose homeostasis. The main goal is to support small, targeted research projects that can address important unanswered questions about why newborns develop low blood glucose, how glucose regulation works (or fails) in the early neonatal period, and what that means for monitoring, diagnosis, and treatment. Even though the field has made progress in understanding causes and mechanisms, NICHD is signaling that meaningful gaps remain and that filling those gaps could directly improve how clinicians identify at-risk infants and manage abnormal glucose levels to prevent complications.
This FOA uses the NIH Small Research Grant mechanism (R03), which is designed for modest-scope projects that can be completed with limited funds and within a relatively short timeframe compared with larger awards. In practice, R03 grants are often used to generate preliminary data, test feasibility, validate an approach, or answer a focused mechanistic or clinical question that does not require the scale of a full R01. NICHD also notes that this R03 announcement runs in parallel with two companion announcements of the same scientific scope that use different mechanisms: PA-11-053 (R01) for full research projects and PA-11-055 (R21) for exploratory or developmental work. That structure gives applicants flexibility to choose the mechanism that best matches the maturity and size of the proposed study while keeping the scientific priorities consistent across programs.
The scientific scope emphasized here spans basic, applied, and translational research related to neonatal hypoglycemia. That typically includes work that investigates the underlying physiology of glucose production and utilization in newborns, the hormonal and metabolic pathways involved, risk factors and clinical trajectories in different neonatal populations, and translational studies that could lead to better tools or strategies for real-world care. The announcement frames the intended impact in practical terms: improving monitoring approaches, sharpening diagnostic criteria or methods, and developing or refining treatment strategies for newborn infants with altered glucose homeostasis. In other words, NICHD is not only interested in describing the problem, but in research that can close knowledge gaps in ways that could plausibly influence clinical decision-making and outcomes.
Funding levels and the number of awards are not fixed in the announcement. Instead, NICHD indicates that award size and project duration may vary depending on the nature and scope of the proposed research. The total amount awarded and the number of funded projects will ultimately depend on the mix of applications received, including their quality, proposed budgets, and timelines. This is typical for NIH program announcements where the institute wants to encourage a range of meritorious proposals rather than pre-committing to a set number of awards.
From an eligibility standpoint, the FOA is broad and inclusive. Eligible applicants include many types of U.S. governmental entities (state, county, city/township, special district), public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status), and for-profit organizations (including small businesses and other for-profits). The eligibility language also explicitly includes a variety of mission-focused and historically underrepresented institution types and community-serving organizations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, and faith-based or community-based organizations. It also allows non-U.S. entities (foreign organizations) and regional organizations, as well as U.S. territories and possessions. There is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of the award.
Administratively, the opportunity is categorized as a discretionary grant within the Health domain (CFDA 93.865, Child Health and Human Development Extramural Research). It was posted on December 2, 2010, with an original and final closing date of May 7, 2014, and it was archived on June 7, 2014. Although the opportunity is no longer active, the archived announcement remains useful as a reference point for NICHD priorities and for understanding how NICHD framed research needs in neonatal hypoglycemia during that period. For applicants or researchers looking for current opportunities, the archived FOA can still help in shaping concepts that align with NICHD interests, even if submission would need to occur under a newer, currently active announcement.
For further details, the source announcement is hosted on the NIH Grants Guide website (the FOA page linked in the listing). The contact information provided is primarily technical support through the NIH Office of Extramural Research (OER) webmaster for issues accessing the electronic announcement or linking to it, rather than a programmatic scientific contact.
Frequently Asked Questions (FAQs)
What is the Studies in Neonatal Hypoglycemia (R03) funding opportunity?
It is an NIH grant announcement titled "Studies in Neonatal Hypoglycemia (R03)" with Funding Opportunity Number PA-11-054. It was issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and focuses on research related to neonatal hypoglycemia and altered neonatal glucose homeostasis.
Which NIH institute is sponsoring this opportunity?
The opportunity is sponsored by NICHD (Eunice Kennedy Shriver National Institute of Child Health and Human Development), part of the National Institutes of Health (NIH).
What research topic is this FOA focused on?
The FOA focuses specifically on neonatal hypoglycemia and, more broadly, the biology and clinical realities of altered neonatal glucose homeostasis in newborns.
What is the main goal of this FOA?
The goal is to support small, targeted research projects that address unanswered questions about why newborns develop low blood glucose, how glucose regulation works (or fails) in the early neonatal period, and what that means for monitoring, diagnosis, and treatment.
What kinds of projects does the R03 mechanism support under this announcement?
This FOA uses the NIH Small Research Grant (R03) mechanism, which is designed for modest-scope projects that can be completed with limited funds and within a relatively short timeframe compared with larger awards. The description highlights uses such as generating preliminary data, testing feasibility, validating an approach, or answering a focused mechanistic or clinical question that does not require the scale of a full R01.
How does this R03 relate to other companion opportunities mentioned in the announcement?
NICHD notes that this R03 announcement runs in parallel with two companion announcements of the same scientific scope but using different mechanisms: PA-11-053 (R01) for full research projects and PA-11-055 (R21) for exploratory or developmental work. Applicants could choose the mechanism that best fits the maturity and size of their proposed study while keeping the scientific priorities consistent.
What types of research are included in the scientific scope?
The scope spans basic, applied, and translational research related to neonatal hypoglycemia. This typically includes studies of newborn glucose production and utilization, hormonal and metabolic pathways, risk factors and clinical trajectories across neonatal populations, and translational work aimed at improving tools or strategies for real-world care.
What practical outcomes or impacts is NICHD aiming for with this research?
The FOA frames impact in practical terms, including improving monitoring approaches, sharpening diagnostic criteria or methods, and developing or refining treatment strategies for newborn infants with altered glucose homeostasis. It emphasizes closing knowledge gaps in ways that could plausibly influence clinical decision-making and outcomes.
Are funding levels and the number of awards fixed?
No. The announcement indicates that award size and project duration may vary depending on the nature and scope of the proposed research, and that the total amount awarded and the number of funded projects depend on the applications received (including quality, budgets, and timelines).
Who is eligible to apply?
Eligibility is broad. Eligible applicants include many types of U.S. governmental entities (state, county, city/township, special district), public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status), and for-profit organizations (including small businesses and other for-profits). The eligibility language also includes non-U.S. entities (foreign organizations) and regional organizations, as well as U.S. territories and possessions.
Does the FOA specifically include historically underrepresented or community-serving institution types?
Yes. The eligibility language explicitly includes institution types and organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, and faith-based or community-based organizations.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of the award.
How is this opportunity categorized administratively?
It is categorized as a discretionary grant within the Health domain and is associated with CFDA 93.865 (Child Health and Human Development Extramural Research).
When was this FOA posted and what were the closing dates?
The FOA was posted on December 2, 2010. It lists an original closing date and a final closing date of May 7, 2014, and it was archived on June 7, 2014.
Is this funding opportunity still active?
No. It is no longer active; it was archived in 2014. The archived announcement can still be useful as a reference for NICHD priorities and for understanding how NICHD framed research needs in neonatal hypoglycemia during that period.
How can the archived FOA still be useful if it is no longer active?
The archived FOA can help researchers shape concepts that align with NICHD interests, even though submission would need to occur under a newer, currently active announcement.
Where can the source announcement be found?
The source announcement is hosted on the NIH Grants Guide website on the FOA page linked in the listing.
What contact information is provided in the announcement?
The contact information provided is primarily technical support through the NIH Office of Extramural Research (OER) webmaster, intended for issues accessing the electronic announcement or linking to it, rather than a programmatic scientific contact.
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| Studies in Neonatal Hypoglycemia (R01) Apply for PA 11 053 Funding Number: PA 11 053 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Studies in Neonatal Hypoglycemia (R21) Apply for PA 11 055 Funding Number: PA 11 055 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $200,000 |
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| Specialized Centers in Research in Pediatric Developmental Pharmacology Program (U54) Apply for RFA HD 10 026 Funding Number: RFA HD 10 026 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $500,000 |
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