Opportunity Information: Apply for PA 14 063
Apply for PA 14 063
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Jan 7, 2014 and posted on Jan 7, 2014.
- Applicants must submit their applications by May 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $100,000.00 in funding.
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education City or township governments Public and State controlled institutions of higher education State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Special district governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Native American tribal governments (Federally recognized) County governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R03) opportunity (Funding Opportunity Number PA 14 063) is an NIH discretionary grant designed to support small, model-driven research projects that explain how people make choices that either increase or reduce HIV risk. The central idea is that decision making is a key bridge between substance use and HIV-related outcomes: the same cognitive and emotional processes that shape substance use and abuse can also shape sexual risk behavior, injection-related risk, and whether someone consistently follows HIV prevention or treatment plans. By improving the scientific understanding of how these decisions happen, the program aims to inform better, more targeted strategies to reduce HIV acquisition and transmission and improve adherence to HIV-related treatments.
The FOA prioritizes research that digs into the mechanisms behind risky decision making rather than simply documenting risk behaviors. Applicants are encouraged to focus on at least one of two broad areas. The first is the study of cognitive, motivational, and emotional mechanisms that influence HIV risk behaviors or treatment noncompliance. This could include, for example, how people weigh immediate rewards against long-term consequences, how stress or mood affects judgment, how impulsivity or sensation seeking shapes choices, or how social context and perceived norms alter risk calculations. The second area emphasizes biological and brain-based systems that underlie decision making, specifically brain neuroendocrine and reinforcement systems and the neural networks associated with these functions. In practice, this means the FOA is interested in research linking decision processes to the brain systems involved in reward, learning, stress regulation, and self-control, with the goal of translating that knowledge into more effective behavioral, clinical, or public health approaches.
Interdisciplinary work is explicitly encouraged, reflecting the reality that HIV risk and substance use are shaped by multiple layers of influence. The FOA welcomes approaches and perspectives drawn from psychology, economics, anthropology, sociology, decision sciences, neuroscience, and computational modeling. This makes the opportunity well-suited to studies that combine methods, such as behavioral tasks plus computational models of choice, or social and contextual measures integrated with neuroscience-informed theories of reinforcement and motivation. The emphasis on model-driven work signals that projects should be grounded in testable theoretical frameworks that can explain why certain decisions occur and predict when risky behaviors or nonadherence are more likely.
Because this is an R03 mechanism, it is tailored to smaller projects that can be completed relatively quickly with limited resources. The FOA highlights several types of projects that fit the R03 format, including pilot and feasibility studies, secondary analyses of existing datasets, small self-contained research projects, and efforts to develop or refine research methods or technologies relevant to this topic. Importantly, the announcement states that animal research should not be proposed, indicating that the scope is intended to remain focused on human-relevant decision processes and their implications for HIV risk and treatment behavior.
From an administrative standpoint, the opportunity is a grant (FundingInstrumentType: Grant) in the Education and Health activity category, and it is associated with CFDA numbers 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs). It does not require cost sharing or matching. The award ceiling listed is $100,000. The FOA was posted and created on January 7, 2014, with an original and current closing date of May 7, 2017, and an archive date of June 7, 2017, meaning the announcement is now historical rather than active, but it remains a useful reference for understanding NIH priorities in this research space and for locating related, more current NIH funding opportunities.
Eligibility is broad and includes many categories of U.S. and non-U.S. applicants. Eligible entities listed include public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) organizations), small businesses, for-profit organizations (including those other than small businesses), local and regional government entities (such as city or township governments, county governments, special district governments, and independent school districts), state governments, public housing authorities/Indian housing authorities, and Native American tribal governments and organizations (including federally recognized tribal governments and other tribal entities). The eligibility section also calls out a range of institution types and organizational categories such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, Asian American and Native American Pacific Islander serving institutions, faith-based and community-based organizations, U.S. territories or possessions, and regional organizations. Foreign organizations and foreign institutions are eligible, as are non-U.S. components of U.S. organizations, and foreign components are allowed as defined by NIH policy.
The sponsoring agency is the National Institutes of Health. The full announcement was provided through the NIH grants guide (linked in the source as http://grants.nih.gov/grants/guide/pa-files/PA-14-063.html). For access or technical issues related to the announcement, the contact listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R03) - PA 14 063
What is this funding opportunity?
It is an NIH discretionary grant opportunity titled "Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R03)" (Funding Opportunity Number PA 14 063). It supports small, model-driven research projects focused on understanding how decision making links substance use/abuse with HIV risk and HIV-related outcomes.
What is the main goal of the opportunity?
The goal is to improve scientific understanding of the cognitive, emotional, motivational, and biological mechanisms that drive decisions that increase or reduce HIV risk, and decisions that affect adherence to HIV prevention or treatment plans. The intent is that stronger mechanistic knowledge will help inform more targeted strategies to reduce HIV acquisition and transmission and improve treatment adherence.
Why does the FOA focus on decision making?
The FOA frames decision making as a bridge between substance use and HIV outcomes. The same processes that shape substance use and abuse can also shape sexual risk behavior, injection-related risk, and whether someone consistently follows HIV prevention or treatment regimens.
What kind of research does the FOA prioritize?
The FOA prioritizes mechanistic research on risky decision making, rather than projects that only document or describe risk behaviors. Projects are expected to be model-driven and grounded in testable theoretical frameworks that can explain and predict decision patterns linked to HIV risk or nonadherence.
What are the two broad scientific areas the FOA encourages applicants to focus on?
Applicants are encouraged to focus on at least one of two areas: (1) cognitive, motivational, and emotional mechanisms influencing HIV risk behaviors or treatment noncompliance; and/or (2) biological and brain-based systems underlying decision making, including neuroendocrine and reinforcement systems and associated neural networks.
What are examples of cognitive or emotional mechanisms that fit this FOA?
Examples mentioned include how people weigh immediate rewards versus long-term consequences, how stress or mood affects judgment, how impulsivity or sensation seeking shapes choices, and how social context and perceived norms influence risk calculations.
What does the FOA mean by biological and brain-based systems?
The FOA highlights interest in brain neuroendocrine and reinforcement systems and the neural networks involved in reward, learning, stress regulation, and self-control, specifically as they relate to decision processes that influence HIV risk or adherence behaviors.
Is interdisciplinary research encouraged?
Yes. Interdisciplinary work is explicitly encouraged, reflecting that HIV risk and substance use are shaped by multiple layers of influence.
Which disciplines or perspectives does the FOA explicitly welcome?
The FOA welcomes approaches from psychology, economics, anthropology, sociology, decision sciences, neuroscience, and computational modeling.
What does "model-driven" research mean in this announcement?
Based on the description provided, "model-driven" signals that projects should be anchored in testable theoretical frameworks that can explain why decisions occur and predict when risky behaviors or nonadherence are more likely.
What is the R03 mechanism and what does it imply for project scope?
The R03 mechanism is tailored to smaller projects intended to be completed relatively quickly with limited resources. The FOA highlights project types that fit this smaller, self-contained format.
What types of projects are specifically highlighted as a good fit for this R03?
The FOA highlights pilot and feasibility studies, secondary analyses of existing datasets, small self-contained research projects, and development or refinement of research methods or technologies relevant to the topic.
Is animal research allowed under this FOA?
No. The announcement states that animal research should not be proposed.
What is the funding instrument type?
The funding instrument type is a Grant.
What activity category is associated with this opportunity?
It is listed in the Education and Health activity category.
What CFDA numbers are associated with this FOA?
The opportunity is associated with CFDA 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs).
Is cost sharing or matching required?
No. The opportunity does not require cost sharing or matching.
What is the award ceiling listed for this FOA?
The award ceiling listed is $100,000.
Is this funding opportunity currently active?
No. The FOA is historical rather than active. It was posted/created on January 7, 2014, with a closing date of May 7, 2017, and an archive date of June 7, 2017.
Why might someone still look at an archived FOA?
Even though it is no longer active, it can still serve as a reference for NIH priorities in this research space and help applicants locate related, more current NIH funding opportunities.
Who is eligible to apply?
Eligibility is broad and includes many categories of U.S. and non-U.S. applicants, spanning academic institutions, nonprofits, businesses, and government entities, as described in the eligibility section.
Are U.S. institutions of higher education eligible?
Yes. Public and private institutions of higher education are listed as eligible entities.
Are nonprofit organizations eligible?
Yes. Nonprofits including 501(c)(3) and certain non-501(c)(3) organizations are listed as eligible.
Are for-profit organizations eligible?
Yes. For-profit organizations, including small businesses and other-than-small-business for-profits, are listed as eligible.
Are government entities eligible?
Yes. Eligible entities include local and regional government entities (including city or township governments, county governments, special district governments, and independent school districts) as well as state governments.
Are public housing authorities eligible?
Yes. Public housing authorities/Indian housing authorities are listed as eligible.
Are Native American tribal governments and organizations eligible?
Yes. Eligibility includes Native American tribal governments and organizations, including federally recognized tribal governments and other tribal entities.
Does the FOA mention eligibility for specific institution types like HBCUs or Hispanic-serving institutions?
Yes. The eligibility section calls out multiple categories, including HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and Asian American and Native American Pacific Islander serving institutions.
Are faith-based and community-based organizations eligible?
Yes. Faith-based and community-based organizations are specifically mentioned as included in the eligibility section.
Are U.S. territories or possessions included in the eligibility list?
Yes. The eligibility section includes U.S. territories or possessions.
Are foreign organizations eligible to apply?
Yes. Foreign organizations and foreign institutions are listed as eligible.
Are non-U.S. components of U.S. organizations allowed?
Yes. Non-U.S. components of U.S. organizations are eligible, and foreign components are allowed as defined by NIH policy.
Which agency sponsors this opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
Where can the full announcement be found?
The full announcement was provided through the NIH grants guide at: http://grants.nih.gov/grants/guide/pa-files/PA-14-063.html
Who is listed as the contact for access or technical issues related to the announcement?
The contact listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
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| Revision Applications for Research on Metabolic Reprogramming to Improve Immunotherapy (P01) Apply for PAR 14 087 Funding Number: PAR 14 087 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Advancing Exceptional Research on HIV/AIDS and Substance Abuse (R01) Apply for RFA DA 15 005 Funding Number: RFA DA 15 005 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| HIV Infection of the Central Nervous System (R01) Apply for PA 14 094 Funding Number: PA 14 094 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Eradication of HIV 1 from Central Nervous System Reservoirs (R01) Apply for PA 14 095 Funding Number: PA 14 095 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer Therapeutics, Imaging Technologies, Interventional Devices, Diagnostics, and Prognostics toward Commercialization Apply for RFA CA 14 002 Funding Number: RFA CA 14 002 Agency: National Institutes of Health Category: Education Health Funding Amount: $1,000,000 |
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| Development of Software and Analysis Methods for Biomedical Big Data in Targeted Areas of High Need (U01) Apply for RFA HG 14 020 Funding Number: RFA HG 14 020 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
| Early Phase Clinical Trials in Imaging and Image Guided Interventions (R21) Apply for PAR 14 013 Funding Number: PAR 14 013 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Family Centered Self Management of Chronic Conditions (R21) Apply for PA 14 113 Funding Number: PA 14 113 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Family Centered Self Management of Chronic Conditions (R01) Apply for PA 14 112 Funding Number: PA 14 112 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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