Opportunity Information: Apply for PA 14 062
Apply for PA 14 062
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Jan 7, 2014 and posted on Jan 7, 2014.
- Applicants must submit their applications by May 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities State governments Native American tribal governments (Federally recognized) Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Small businesses Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The National Institutes of Health funding opportunity PA 14 062, titled "Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R21)," supports exploratory, model-driven research focused on how people make decisions that affect HIV outcomes. The central idea is that the same decision-making processes that contribute to substance use and abuse can also shape behaviors that increase the likelihood of acquiring or transmitting HIV, as well as behaviors tied to HIV treatment adherence. The FOA is aiming to move beyond purely descriptive studies by encouraging research grounded in explicit models of decision making, with the longer-term goal of generating practical insights that can be translated into better prevention and intervention strategies.
The scientific emphasis is on understanding decision making as a set of measurable mechanisms that operate at multiple levels, including cognitive, motivational, and emotional processes. Applications are encouraged to examine how factors like impulsivity, reward sensitivity, stress reactivity, affective states, social context, and perceived risk influence choices such as condom use, needle sharing, partner selection, engagement in prevention services, or following HIV treatment plans. Alongside these behavioral and psychological dimensions, the FOA also highlights biological pathways, particularly brain neural networks and related neuroendocrine and reinforcement systems. In practice, this opens the door to studies that connect behavioral choices to brain function and physiology, including how reward circuitry, stress hormones, and reinforcement learning processes may push decision making toward short-term rewards even when long-term health risks are high.
A major feature of this opportunity is its clear preference for interdisciplinary approaches. NIH explicitly encourages teams to combine methods and perspectives from psychology, economics, anthropology, sociology, decision sciences, neuroscience, and computational modeling. That could include, for example, integrating behavioral economics tasks with neuroimaging, using computational models to quantify learning and valuation processes, or combining qualitative social and cultural analysis with experimentally measured decision parameters. The FOA is set up to welcome innovative measurement strategies and novel conceptual frameworks that help explain why risk-relevant decisions occur in real-world settings, especially when substance use is involved.
Because this is an R21 mechanism, the program is designed for exploratory and developmental projects, meaning it is appropriate for early-stage ideas, pilot studies, proof-of-concept work, and the development of new tools or models. NIH signals that these projects may involve higher risk than a typical confirmatory study, but they are valued because they can produce breakthroughs, open up new lines of inquiry, or generate new techniques, methodologies, models, or applications with major impact on HIV prevention and treatment outcomes. The award ceiling listed is $200,000, and the FOA indicates no cost sharing or matching requirement.
From an administrative standpoint, this is a discretionary grant opportunity in the education and health activity space, associated with CFDA numbers 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs). It was posted January 7, 2014, with an original and current closing date of May 7, 2017, and an archive date of June 7, 2017. While those dates indicate the announcement is archived, the summary reflects what the FOA was designed to fund during its active period.
Eligibility is broad and includes many types of U.S. and non-U.S. organizations. Eligible applicants include public and private institutions of higher education, state and local governments (including counties, cities, townships, special districts), independent school districts, public housing authorities, federally recognized and other tribal governments and tribal organizations, nonprofits with or without 501(c)(3) status, for-profit organizations (other than small businesses), and small businesses. The FOA also explicitly includes a range of mission- and community-focused institutions such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and AANAPISI institutions, as well as faith-based and community-based organizations. Foreign organizations and foreign institutions are eligible to apply, non-U.S. components of U.S. organizations are eligible, and foreign components are allowed as defined by the NIH Grants Policy Statement.
For applicants who needed the full official details, the FOA provided an announcement link at http://grants.nih.gov/grants/guide/pa-files/PA-14-062.html and directed technical access questions to the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: NIH PA-14-062 - Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R21)
1) What is the title and identifier of this NIH funding opportunity?
The funding opportunity is NIH FOA PA-14-062, titled "Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R21)."
2) What is the main purpose of PA-14-062?
The purpose is to support exploratory, model-driven research on decision-making processes that affect HIV outcomes. The FOA is centered on the idea that mechanisms influencing substance use and abuse decisions can also shape HIV-related behaviors, including behaviors that increase the risk of acquiring or transmitting HIV and behaviors tied to HIV treatment adherence.
3) What kind of research approach does the FOA emphasize?
The FOA emphasizes moving beyond purely descriptive studies by encouraging research grounded in explicit models of decision making. The longer-term goal is to produce insights that can be translated into improved HIV prevention and intervention strategies.
4) What types of decisions or behaviors are in scope for this opportunity?
The FOA highlights HIV-relevant choices such as condom use, needle sharing, partner selection, engagement in prevention services, and adherence to HIV treatment plans, particularly in contexts where substance use is involved.
5) What decision-making mechanisms does NIH want applicants to study?
NIH is interested in measurable mechanisms operating at multiple levels, including cognitive, motivational, and emotional processes. Examples of factors called out include impulsivity, reward sensitivity, stress reactivity, affective states, social context, and perceived risk, and how these factors influence HIV-related risk and treatment decisions.
6) Does the FOA include biological or neuroscience components?
Yes. The FOA highlights biological pathways, including brain neural networks and related neuroendocrine and reinforcement systems. It explicitly supports research linking behavioral choices to brain function and physiology, such as reward circuitry, stress hormones, and reinforcement learning processes that may bias decisions toward short-term rewards despite long-term health risks.
7) Is interdisciplinary research encouraged?
Yes. A major feature of the FOA is a clear preference for interdisciplinary approaches. NIH encourages combining methods and perspectives from areas such as psychology, economics, anthropology, sociology, decision sciences, neuroscience, and computational modeling.
8) What are examples of interdisciplinary methods that fit the FOA?
The FOA mentions examples like integrating behavioral economics tasks with neuroimaging, using computational models to quantify learning and valuation processes, and combining qualitative social/cultural analysis with experimentally measured decision parameters.
9) What is the grant mechanism and what does it imply about project type?
This is an R21 mechanism, which is designed for exploratory and developmental projects. The FOA describes it as appropriate for early-stage ideas, pilot studies, proof-of-concept work, and development of new tools or models. It also signals that higher-risk projects may be appropriate if they can open new lines of inquiry or generate impactful techniques or methodologies.
10) What is the maximum award amount mentioned in the FOA?
The award ceiling listed is $200,000.
11) Is cost sharing or matching required?
No. The FOA indicates there is no cost sharing or matching requirement.
12) What is the activity area or general category of this opportunity?
Administratively, it is described as a discretionary grant opportunity in the education and health activity space.
13) What CFDA numbers are associated with this opportunity?
The FOA is associated with CFDA 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs).
14) When was PA-14-062 posted, and what were the closing and archive dates?
It was posted January 7, 2014. The original and current closing date listed was May 7, 2017, and the archive date was June 7, 2017. These dates indicate the announcement is archived, and the summary reflects what it was designed to fund during its active period.
15) Is this FOA still active?
Based on the provided dates (closing date May 7, 2017 and archive date June 7, 2017), the announcement is archived rather than active.
16) Who is eligible to apply?
Eligibility is broad and includes many types of U.S. and non-U.S. organizations. Examples include public and private institutions of higher education; state and local governments (including counties, cities, townships, and special districts); independent school districts; public housing authorities; federally recognized tribal governments and other tribal governments; tribal organizations; nonprofits with or without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses.
17) Are minority-serving institutions and community-focused organizations included in eligibility?
Yes. The FOA explicitly includes institutions such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and AANAPISI institutions. It also includes faith-based and community-based organizations.
18) Can foreign organizations apply?
Yes. Foreign organizations and foreign institutions are eligible to apply. Non-U.S. components of U.S. organizations are eligible, and foreign components are allowed as defined by the NIH Grants Policy Statement.
19) What kinds of innovations does the FOA encourage?
The FOA welcomes innovative measurement strategies and novel conceptual frameworks that explain why risk-relevant decisions occur in real-world settings, particularly when substance use is involved. It also values new techniques, methodologies, models, or applications that could have major impact on HIV prevention and treatment outcomes.
20) Where can applicants find the official FOA announcement text?
The FOA link provided is: http://grants.nih.gov/grants/guide/pa-files/PA-14-062.html
21) Who is listed for technical access questions about the announcement?
For technical access questions, the FOA directed users to the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
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