Opportunity Information: Apply for CDC RFA PS10 1049

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Support for Strengthening and Expanding Comprehensive HIV and AIDS Prevention Programs in the Republic of South Africa Under the President s Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067 Global AIDS.
  • This funding opportunity was created on Feb 11, 2010 and posted on Feb 11, 2010.
  • Applicants must submit their applications by Apr 8, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $4,696,750.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $750,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Eligible applicants that can apply for this funding opportunity are listed below Public nonprofit organizations Private nonprofit organizations For profit organizations Small, minority, women owned business Universities Colleges Research institutions Hospitals Community based organizations Faith based organizations Federally recognized Indian tribal organizations Alaska Native tribal governments Indian tribes Tribal Epidemiology centers Indian tribal organizations State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau) Political subdivisions of States (in consultation with States) Non domestic (non U.S.) entity A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a letter from the state or local government as documentation of the status is required. Attach with Other Attachment Forms when submitting via www.grants.gov.
Apply for CDC RFA PS10 1049

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Opportunity Summary:

The CDC funding opportunity CDC RFA PS10-1049 is a PEPFAR-supported cooperative agreement aimed at strengthening and expanding comprehensive HIV and AIDS prevention efforts in the Republic of South Africa. The grant is designed to provide both financial and programmatic support to an organization already active in HIV/AIDS prevention, care, and treatment, with an emphasis on helping the United States Government and the South African Government scale up and improve HIV-related activities carried out under the President's Emergency Plan for AIDS Relief (PEPFAR). A central requirement is that all supported work must align with South Africa's Department of Health policies, guidelines, and clinical protocols, meaning the awardee is expected to operate within the national and provincial public health framework rather than running disconnected, parallel services.

A key programmatic focus is improving prevention of mother-to-child transmission (PMTCT) services in ways that are specifically youth-friendly. In practice, this means the recipient is expected to provide technical assistance and hands-on support that strengthens service delivery and increases uptake among adolescents and young people, a group that often faces barriers such as stigma, limited access to tailored counseling, inconvenient clinic hours, and low retention in care. The recipient will not work in isolation; the award is structured around close collaboration with South Africa's national and provincial Departments of Health, the USG PEPFAR task force, and CDC South Africa. Because the mechanism is a cooperative agreement, CDC typically has substantial involvement in program direction, monitoring, and coordination, and the grantee is generally expected to participate actively in joint planning, reporting, and performance improvement with USG partners.

The opportunity sits under the health funding category and is tied to CFDA number 93.067 (Global AIDS). The program anticipated a single award, reflecting a concentrated investment in one implementing partner to drive a specific technical assistance agenda. The estimated total funding listed is $4,696,750, while the stated award ceiling and floor are both $750,000, indicating that the intended award size for the main budget period was set at $750,000, with additional context likely handled through the project period structure or incremental funding approach typical of cooperative agreements. There is no cost-sharing or matching requirement, which lowers the financial barrier for applicants and allows organizations to focus resources on implementation and technical support rather than raising matching funds.

Eligibility was broad and included public and private nonprofit organizations, for-profit organizations (including small, minority-, and women-owned businesses), universities and colleges, research institutions, hospitals, community-based and faith-based organizations, tribal entities and tribal epidemiology centers, and state/local governments or their bona fide agents, as well as non-U.S. (non-domestic) entities. The listing also explains that bona fide agents applying on behalf of a state or local government must provide documentation (a letter) verifying that status when applying through Grants.gov. This wide eligibility set suggests the CDC was open to a range of organizational types as long as the applicant could demonstrate the technical capacity to support PMTCT and broader HIV program strengthening in South Africa and manage cooperative agreement requirements.

The opportunity was posted on February 11, 2010, with an application closing date of April 8, 2010, and an archive date of May 8, 2010. The funding agency is the Centers for Disease Control and Prevention. For applicants who had trouble accessing the full announcement, the contact provided was the PGO TIMS Grants office at 770-488-2700, with a general email also referenced. Overall, the grant is best understood as a targeted PEPFAR implementation support award focused on reinforcing South Africa's HIV response through coordinated technical assistance, with a particular priority on strengthening youth-friendly PMTCT services to improve both service quality and utilization.

Frequently Asked Questions (FAQs)

What is CDC RFA PS10-1049?

CDC RFA PS10-1049 is a PEPFAR-supported cooperative agreement from the Centers for Disease Control and Prevention (CDC) focused on strengthening and expanding comprehensive HIV and AIDS prevention efforts in the Republic of South Africa.

What is the main goal of this funding opportunity?

The main goal is to provide financial and programmatic support to an organization already working in HIV/AIDS prevention, care, and treatment, so it can help the United States Government (USG) and the South African Government scale up and improve HIV-related activities carried out under the President's Emergency Plan for AIDS Relief (PEPFAR).

What type of award is this?

This opportunity is a cooperative agreement, which typically means CDC has substantial involvement in program direction, coordination, monitoring, and performance improvement alongside the recipient.

Where will the supported activities take place?

The work is focused in the Republic of South Africa and is intended to operate within South Africa's national and provincial public health framework.

What is a central requirement for program alignment?

All supported work must align with South Africa's Department of Health policies, guidelines, and clinical protocols. The recipient is expected to strengthen public health services rather than run disconnected, parallel services.

What program area is specifically highlighted as a priority?

A key priority is improving prevention of mother-to-child transmission (PMTCT) services in ways that are specifically youth-friendly.

What does "youth-friendly PMTCT" mean in this opportunity?

Based on the description, youth-friendly PMTCT involves technical assistance and hands-on support that improves service delivery and increases uptake among adolescents and young people, recognizing common barriers such as stigma, limited access to tailored counseling, inconvenient clinic hours, and low retention in care.

Is this award meant to be implemented independently by the recipient?

No. The opportunity is structured around close collaboration with South Africa's national and provincial Departments of Health, the USG PEPFAR task force, and CDC South Africa.

What does collaboration look like under this cooperative agreement?

The recipient is generally expected to participate actively in joint planning, reporting, coordination, and performance improvement activities with USG partners and relevant South African government counterparts.

What funding category and CFDA number are associated with this opportunity?

The opportunity is under the health funding category and is tied to CFDA number 93.067 (Global AIDS).

How many awards were anticipated?

The program anticipated a single award, indicating a concentrated investment in one implementing partner.

What is the estimated total funding listed for the opportunity?

The estimated total funding listed is $4,696,750.

What are the award ceiling and floor?

The stated award ceiling and award floor are both $750,000, indicating the intended award size for the main budget period was set at $750,000.

Does the opportunity mention anything about incremental funding or project period structure?

Yes. The description notes that the difference between the estimated total funding and the stated ceiling/floor suggests additional context likely handled through a project period structure or an incremental funding approach typical of cooperative agreements.

Is cost sharing or matching required?

No. There is no cost-sharing or matching requirement stated for this opportunity.

Who is eligible to apply?

Eligibility is broad and includes public and private nonprofit organizations, for-profit organizations (including small, minority-, and women-owned businesses), universities and colleges, research institutions, hospitals, community-based and faith-based organizations, tribal entities and tribal epidemiology centers, and state/local governments or their bona fide agents. Non-U.S. (non-domestic) entities are also eligible.

Are non-U.S. (non-domestic) organizations eligible?

Yes. The opportunity explicitly includes non-U.S. (non-domestic) entities in the eligible applicant types.

What is required if a bona fide agent applies on behalf of a state or local government?

The listing states that bona fide agents must provide documentation (a letter) verifying their status when applying through Grants.gov.

What kind of organization does this opportunity seem designed for?

It is designed to support an organization already active in HIV/AIDS prevention, care, and treatment, with the technical capacity to support PMTCT and broader HIV program strengthening in South Africa and to manage cooperative agreement requirements.

When was the opportunity posted, and what were the key dates?

The opportunity was posted on February 11, 2010. The application closing date was April 8, 2010, and the archive date was May 8, 2010.

Which agency is funding this opportunity?

The funding agency is the Centers for Disease Control and Prevention (CDC).

Where can applicants get help if they cannot access the full announcement?

For applicants who had trouble accessing the full announcement, the contact provided was the PGO TIMS Grants office at 770-488-2700, and a general email was also referenced in the listing.

How does this opportunity fit into PEPFAR activities?

The award is intended to help the USG and the South African Government scale up and improve HIV-related activities carried out under PEPFAR, with a targeted focus on coordinated technical assistance and strengthening youth-friendly PMTCT services.

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