Opportunity Information: Apply for PAR 11 220

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Support of NIGMS Program Project Grants (P01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research 93.859 Biomedical Research and Research Training.
  • This funding opportunity was created on Jul 19, 2013 and posted on May 31, 2011.
  • Applicants must submit their applications by Jul 19, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $6,500,000.00 to eligible and selected applicants.
  • Eligible applicants include: City or township governments For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses County governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Organizations) are not eligible to apply. However, such institutions may participate as members of consortia or subcontractors on the application. Foreign (non U.S.) components of U.S. Organizations are not allowed.
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Opportunity Summary:

Support of NIGMS Program Project Grants (P01) (Funding Opportunity Number PAR-11-220) is a National Institutes of Health (NIH) discretionary grant opportunity administered through the National Institute of General Medical Sciences (NIGMS). It is designed for institutions that want to tackle a major biological question that aligns with the NIGMS mission by using a coordinated, team-based structure rather than isolated single-investigator awards. The central idea is that some scientific problems are best solved when multiple research efforts are deliberately organized to work together, share ideas and resources, and generate results that would be harder, slower, or less impactful if each project were funded and run independently.

This FOA specifically encourages program project grant (P01) applications that are innovative and genuinely interactive. In a P01, several research projects are funded as a single, integrated program, typically built around a unifying theme or overarching biological problem. The expectation is that the proposed component projects are interdependent and collaborative in a way that produces clear scientific advantages. In other words, the application should make a convincing case that the whole program is greater than the sum of its parts, such as through shared conceptual frameworks, complementary expertise, coordinated experimental strategies, and active collaboration among investigators who may not normally work together. NIGMS is signaling that it values outstanding scientists joining forces in a structured way to drive progress on significant, broadly relevant biological questions.

The activity areas tied to this announcement fall under NIH health-related research and training categories, with CFDA numbers listed as 93.172 (Human Genome Research) and 93.859 (Biomedical Research and Research Training). Cost sharing or matching is not required, which means applicants are not obligated to contribute non-federal funds as a condition of receiving the award. The estimated total funding amount listed for the opportunity is $6,500,000, indicating a meaningful investment intended to support a set of coordinated program projects rather than stand-alone grants.

Eligibility is broad and spans many organization types. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education, as well as nonprofits (including 501(c)(3) and non-501(c)(3) organizations), small businesses, and for-profit organizations other than small businesses. Various government entities may apply, including state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The eligibility list also explicitly includes a range of mission-focused or community-linked institution categories, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. Foreign (non-U.S.) entities are not eligible to apply as the primary applicant. However, foreign organizations may participate as part of a consortium or as subcontractors, while foreign components of U.S. organizations are not permitted under the stated rules.

From a timing and administrative standpoint, the FOA was posted on May 31, 2011, with key lifecycle dates indicating it later entered an archived status (archive date August 19, 2013). The source data also shows a current closing date of July 19, 2013 and an original closing date of September 7, 2014, which suggests the listing reflects an opportunity record that has been updated over time and is no longer active. For applicants or researchers looking to understand the detailed program expectations, application structure, and review criteria that govern P01 submissions, the official NIH Grants Guide posting is provided via the additional information link (http://grants.nih.gov/grants/guide/pa-files/PAR-11-220.html). For technical access issues related to the announcement, the listed point of contact is the NIH Office of Extramural Research (OER) Webmaster (FBOWebmaster@OD.NIH.GOV).

Frequently Asked Questions (FAQs)

What is the "Support of NIGMS Program Project Grants (P01)" opportunity?

This opportunity (Funding Opportunity Number PAR-11-220) is a National Institutes of Health (NIH) discretionary grant administered by the National Institute of General Medical Sciences (NIGMS). It supports program project grants (P01) intended to fund a single, integrated research program made up of multiple component projects working together on a major biological question aligned with the NIGMS mission.

What is the main purpose of this FOA?

The FOA is designed for institutions that want to address a significant biological problem using a coordinated, team-based structure rather than separate, single-investigator awards. The emphasis is on intentionally organized collaboration that produces stronger, faster, or more impactful outcomes than independent projects would achieve on their own.

What kind of applications does NIGMS encourage under this announcement?

NIGMS encourages P01 applications that are innovative, genuinely interactive, and built around a unifying theme or overarching biological question. The component projects are expected to be collaborative and interdependent, with clear scientific advantages that come specifically from being organized as one program.

What does "the whole is greater than the sum of its parts" mean in this context?

In this FOA, it means the application should make a convincing case that the integrated program produces benefits that would be harder, slower, or less impactful if each project were funded and run independently. Examples described in the opportunity include shared conceptual frameworks, complementary expertise, coordinated experimental strategies, shared ideas and resources, and active collaboration among investigators (including investigators who may not normally work together).

What is a P01 (Program Project Grant) as described here?

A P01 is described as a single, integrated grant that supports several research projects as one coordinated program. Rather than being isolated efforts, the component projects are structured to work together around an overarching problem or theme and to deliver clear advantages through collaboration and shared resources.

What scientific scope or mission alignment is expected?

The supported work is intended to tackle a major biological question that aligns with the NIGMS mission. The opportunity emphasizes significance and broad biological relevance, paired with a coordinated team structure.

What activity areas or categories are associated with this FOA?

The announcement is tied to NIH health-related research and training categories. The listed CFDA numbers are 93.172 (Human Genome Research) and 93.859 (Biomedical Research and Research Training).

Is cost sharing or matching required?

No. The opportunity states that cost sharing or matching is not required, meaning applicants are not obligated to contribute non-federal funds as a condition of receiving an award.

How much funding is associated with this opportunity?

The estimated total funding amount listed is $6,500,000. The description frames this as a meaningful investment intended to support coordinated program projects rather than stand-alone grants.

Who is eligible to apply?

Eligibility is broad and includes many types of U.S.-based organizations. The opportunity lists eligible applicants such as public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including 501(c)(3) and non-501(c)(3)), small businesses, and for-profit organizations other than small businesses.

Are government entities eligible applicants?

Yes. The eligibility list includes multiple government entity types, including state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities.

Are mission-focused or community-linked institutions eligible?

Yes. The eligibility list explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.

Are foreign (non-U.S.) organizations eligible to apply as the primary applicant?

No. The opportunity states that foreign (non-U.S.) entities are not eligible to apply as the primary applicant.

Can foreign organizations participate in any way?

Yes. While foreign entities are not eligible to apply as the primary applicant, the opportunity states that foreign organizations may participate as part of a consortium or as subcontractors.

Are foreign components of U.S. organizations allowed?

No. The opportunity states that foreign components of U.S. organizations are not permitted.

Is this funding opportunity currently active?

The record indicates the FOA was posted on May 31, 2011 and later entered archived status (archive date August 19, 2013). The source data also shows a current closing date of July 19, 2013, suggesting the opportunity is no longer active.

Why are there multiple closing dates shown?

The listing shows a current closing date of July 19, 2013 and an original closing date of September 7, 2014. Based on the information provided, this suggests the opportunity record was updated over time and reflects an archived (no longer active) opportunity.

Where can applicants find the official NIH program details and requirements?

The announcement directs users to the official NIH Grants Guide posting for detailed expectations, application structure, and review criteria: http://grants.nih.gov/grants/guide/pa-files/PAR-11-220.html

Who is the contact for technical access issues related to the announcement?

The listed point of contact for technical access issues is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

Which NIH institute administers this FOA?

This opportunity is administered through the National Institute of General Medical Sciences (NIGMS) within NIH.

What kinds of collaboration features are highlighted as valuable?

The opportunity emphasizes deliberate organization of multiple research efforts to share ideas and resources, coordinate strategies, combine complementary expertise, and actively collaborate in ways that generate clear scientific advantages compared with independent funding and execution.

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