Opportunity Information: Apply for RFA DP10 001

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Surveillance, Natural History, Quality of Care and Outcomes of Diabetes Mellitus with Onset in Childhood and Adolescence (U 18)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.945 Assistance Programs for Chronic Disease Prevention and Control.
  • This funding opportunity was created on Apr 23, 2010 and posted on Feb 10, 2010.
  • Applicants must submit their applications by Apr 30, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $16,000,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 6 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Public nonprofit organizations Private nonprofit organizations For profit organizations Small, minority, and women owned businesses Universities Colleges Research institutions Hospitals Community based organizations Faith based organizations Federally recognized or state recognized American Indian/Alaska Native tribal governments American Indian/Alaska Native tribally designated organizations Alaska Native health corporations Urban Indian health organizations Tribal epidemiology centers State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau) Political subdivisions of States (in consultation with States) A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If you are applying as a bona fide agent of a state or local government, you must provide a letter from the state or local government as documentation of your status. Attach this documentation behind the first page of your application form or for electronic applications, use a PDF file and attach as Other Documents and label as appropriate.
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Opportunity Summary:

The grant opportunity titled "Surveillance, Natural History, Quality of Care and Outcomes of Diabetes Mellitus with Onset in Childhood and Adolescence (U 18)" (Funding Opportunity Number RFA DP10-001) is a Centers for Disease Control and Prevention (CDC) cooperative agreement focused on understanding diabetes that begins in childhood and adolescence, meaning diagnosis before age 20. The overall purpose is to strengthen population-based knowledge about how often youth diabetes occurs, how it changes over time, and what happens to people who develop diabetes early in life as they move through adolescence into young adulthood. The work is framed around producing reliable, actionable public health evidence, while emphasizing approaches that are efficient and relatively low-cost, especially for surveillance activities.

A core component of the opportunity is surveillance: applicants are expected to estimate temporal trends in diabetes incidence among U.S. youth, breaking results down by diabetes type and by race/ethnicity. In practical terms, this means building or using population-based case-finding and data systems that can track new diagnoses over time, not just single snapshots, and doing so in a way that can support ongoing monitoring. The program explicitly highlights the need for methods that are both effective and economical, signaling interest in surveillance strategies that can be sustained, replicated, and scaled without relying on extremely expensive data collection models.

A second major focus is the natural history and long-term impact of diabetes that starts early in life. The CDC is looking for studies that follow or assess individuals diagnosed in childhood or adolescence to understand outcomes over the longer term. This includes measuring health-related perceived quality of life, which brings patient-centered outcomes into the program rather than limiting it to clinical endpoints alone. The grant also calls for assessing the incidence of acute and chronic complications, along with identifying risk factors for those complications, again stratified by diabetes type and race/ethnicity. The emphasis on both complications and risk factors suggests that projects should not only document what problems occur, but also analyze why they occur and which groups are most affected, with the goal of informing prevention strategies and improving long-term management.

A third focus area targets the transition period when adolescents with diabetes become young adults and move from pediatric to adult healthcare settings. For young adults who developed diabetes earlier in life, the program aims to assess access to care and the quality of care during this transition. This is a well-known vulnerable period when continuity can break down, adherence can shift, and complications can emerge or accelerate. The opportunity indicates interest in understanding whether young adults are able to obtain appropriate adult specialty or primary care, how smoothly care is transferred, and what the quality of ongoing diabetes management looks like during and after the transition, potentially including gaps, disparities, and system-level barriers.

Administratively, this is a discretionary funding opportunity using a cooperative agreement mechanism, which typically means CDC expects substantial involvement in the funded work beyond what occurs in a standard grant. The program anticipated about six awards, with an estimated total funding amount of $16,000,000. No cost sharing or matching is required. While award floor and ceiling are listed as $0 in the notice, that usually reflects how the announcement was posted rather than indicating that awards are unfunded; the total and expected number of awards provide the more meaningful scale.

Eligibility is broad and includes public and private nonprofit organizations, for-profit organizations (including small, minority-, and women-owned businesses), universities and colleges, research institutions, hospitals, community-based and faith-based organizations, tribal governments and tribal health entities, tribal epidemiology centers, urban Indian health organizations, Alaska Native health corporations, and state/local governments and their bona fide agents. The notice specifies that bona fide agents applying on behalf of a state or local government must provide documentation (a letter) confirming that status as part of the application. This wide eligibility signals that CDC is open to partnerships across academic, clinical, public health, and community/tribal systems, as long as applicants can credibly carry out population-based surveillance and outcomes research with appropriate expertise and infrastructure.

Key dates included a posted date of February 10, 2010, with an original closing date of March 17, 2010, later extended to April 30, 2010, and an archive date of May 30, 2010. The administering agency is CDC, and the CFDA number listed is 93.945 (Assistance Programs for Chronic Disease Prevention and Control). For help accessing the full announcement, the contact point was CDC PGOTIM, Technical Information Management Section (TIMS), at 770-488-2700.

Taken together, the opportunity is essentially seeking coordinated, population-based work that can answer three big public health questions: how youth diabetes incidence is changing over time and across demographic groups; what the long-term health and quality-of-life outcomes look like for people diagnosed early; and how well the healthcare system supports these individuals as they transition into adult care, including whether access and quality differ by diabetes type and race/ethnicity. The consistent thread across all aims is producing evidence that can guide prevention, clinical care planning, and equity-focused public health action for diabetes beginning in childhood and adolescence.

FAQs: Surveillance, Natural History, Quality of Care and Outcomes of Diabetes Mellitus with Onset in Childhood and Adolescence (U 18) (RFA DP10-001)

What is the title of this grant opportunity?

The opportunity is titled "Surveillance, Natural History, Quality of Care and Outcomes of Diabetes Mellitus with Onset in Childhood and Adolescence (U 18)."

What is the Funding Opportunity Number?

The Funding Opportunity Number is RFA DP10-001.

Which federal agency is offering this opportunity?

The administering agency is the Centers for Disease Control and Prevention (CDC).

What funding mechanism is being used?

This opportunity uses a cooperative agreement mechanism (a discretionary funding opportunity). This typically indicates CDC expects substantial involvement in the funded work beyond what occurs in a standard grant.

What is the overall purpose of the program?

The purpose is to strengthen population-based knowledge about diabetes that begins in childhood and adolescence (diagnosis before age 20), including how often it occurs, how incidence changes over time, and what outcomes look like as affected individuals move through adolescence into young adulthood.

What age group does "U 18" refer to in the title?

Based on the description, the program focuses on diabetes with onset in childhood and adolescence and defines onset as diagnosis before age 20.

What are the main topic areas or components of the work?

The work is framed around three major areas: (1) surveillance of youth diabetes incidence over time, (2) natural history and long-term outcomes (including quality of life and complications), and (3) access to care and quality of care during the transition from pediatric to adult health care.

What does the program mean by "surveillance" in this context?

Surveillance refers to estimating temporal trends in diabetes incidence among U.S. youth using population-based case-finding and data systems that can track new diagnoses over time (not just one-time snapshots) and support ongoing monitoring.

What specific surveillance results are expected?

Applicants are expected to estimate temporal trends in diabetes incidence among U.S. youth, with results broken down by diabetes type and by race/ethnicity.

Does the opportunity emphasize any particular approach to surveillance?

Yes. The program emphasizes methods that are efficient and relatively low-cost, signaling interest in surveillance strategies that are sustainable, replicable, and scalable without relying on extremely expensive data collection models.

What does "natural history" mean for this opportunity?

Natural history refers to understanding the longer-term course and impact of diabetes that starts early in life, including outcomes as individuals age from adolescence into young adulthood.

What outcomes does CDC want studied under the natural history focus area?

The program calls for measuring health-related perceived quality of life, assessing the incidence of acute and chronic complications, and identifying risk factors for those complications, stratified by diabetes type and race/ethnicity.

Is quality of life included as an outcome?

Yes. The opportunity explicitly includes measuring health-related perceived quality of life, reflecting a patient-centered outcomes emphasis alongside clinical endpoints.

Does the opportunity require analysis by diabetes type?

Yes. Both the surveillance component and the complications/risk factor assessments are expected to be stratified by diabetes type.

Does the opportunity require analysis by race/ethnicity?

Yes. The surveillance results and the complications/risk factor assessments are expected to be stratified by race/ethnicity.

What is the third focus area about the transition to adult care?

The third focus area targets the transition period when adolescents with diabetes become young adults and move from pediatric to adult healthcare settings, with an emphasis on evaluating access to care and quality of care during and after this transition.

What kinds of transition-related questions is CDC interested in?

The opportunity indicates interest in whether young adults can obtain appropriate adult specialty or primary care, how smoothly care is transferred, and what the quality of ongoing diabetes management looks like during and after the transition, including potential gaps, disparities, and system-level barriers.

How many awards did CDC anticipate making?

The program anticipated about six awards.

What was the estimated total funding amount?

The estimated total funding amount was $16,000,000.

Is cost sharing or matching required?

No. The announcement states that no cost sharing or matching is required.

Why do the award floor and ceiling show $0?

The notice lists an award floor and ceiling of $0, but the description notes this likely reflects how the announcement was posted rather than indicating awards are unfunded. The total estimated funding and expected number of awards provide the more meaningful scale.

Who is eligible to apply?

Eligibility is broad and includes public and private nonprofit organizations, for-profit organizations (including small, minority-, and women-owned businesses), universities and colleges, research institutions, hospitals, community-based and faith-based organizations, tribal governments and tribal health entities, tribal epidemiology centers, urban Indian health organizations, Alaska Native health corporations, and state/local governments and their bona fide agents.

Can for-profit organizations apply?

Yes. For-profit organizations are included in the eligibility list, including small, minority-, and women-owned businesses.

Are tribal entities eligible?

Yes. The eligibility list includes tribal governments and tribal health entities, tribal epidemiology centers, urban Indian health organizations, and Alaska Native health corporations.

What does "bona fide agent" mean for eligibility, and is any documentation required?

The notice states that bona fide agents applying on behalf of a state or local government must provide documentation (a letter) confirming that status as part of the application.

What CFDA number is associated with this opportunity?

The CFDA number listed is 93.945 (Assistance Programs for Chronic Disease Prevention and Control).

When was the opportunity posted?

The posted date was February 10, 2010.

What was the original closing date and the extended closing date?

The original closing date was March 17, 2010, and it was later extended to April 30, 2010.

When was the opportunity archived?

The archive date was May 30, 2010.

Where could applicants get technical help accessing the full announcement?

The contact point listed was CDC PGOTIM, Technical Information Management Section (TIMS), at 770-488-2700.

What public health questions is this program trying to answer?

The opportunity is aimed at answering three central questions: (1) how youth diabetes incidence is changing over time and across demographic groups, (2) what long-term health and quality-of-life outcomes look like for people diagnosed early, and (3) how well the healthcare system supports these individuals as they transition into adult care, including whether access and quality differ by diabetes type and race/ethnicity.

What kind of evidence is CDC seeking from funded projects?

The program emphasizes producing reliable, actionable public health evidence that can guide prevention, clinical care planning, and equity-focused public health action for diabetes beginning in childhood and adolescence.

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