Opportunity Information: Apply for RFA HD 10 001

  • The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Systems Oriented Pediatric Obesity Research and Training (SPORT) Center of Excellence (U54)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Sep 23, 2010 and posted on Sep 23, 2010.
  • Applicants must submit their applications by Dec 30, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $4,250,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments County governments Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Eligible Agencies of the Federal Government Regional Organizations.
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Opportunity Summary:

The Systems Oriented Pediatric Obesity Research and Training (SPORT) Center of Excellence (U54) funding opportunity, issued by the National Institutes of Health through NICHD in partnership with NCI and OBSSR, was designed to create a single, high-impact center focused on childhood obesity using a systems science approach. The main idea behind the announcement is that pediatric obesity is driven by a complicated web of interacting influences, including biology, behavior, family and community context, the built environment, food systems, and broader social and policy conditions. Rather than treating these drivers as isolated risk factors, the SPORT center model emphasizes transdisciplinary research that can represent these interactions explicitly, particularly through systems-based methods and systems modeling. Applicants were expected to build an integrated research and training enterprise capable of capturing the complexity of obesity etiology and forecasting or estimating the likely effects of environmental and policy interventions.

A key feature of the program is the expectation that the center would be organized as a partnership between U.S. institutions and international institutions. This structure reflects the premise that understanding and preventing childhood obesity benefits from comparing contexts, policies, and environments across countries, and from building shared research capacity and methods that are transferable across settings. Within this collaborative framework, the center would pursue epidemiological research that links biological factors to environmental exposures and macro-social determinants, moving beyond individual-level explanations and toward multi-level causal models. In addition to observational and etiologic work, the center was also expected to support the design, evaluation, and testing of environmental and policy approaches, such as interventions tied to schools, neighborhoods, food environments, transportation and physical activity infrastructure, marketing environments, or broader policy changes. Importantly, the FOA highlights developmental research funding, meaning the center would not only run core projects but also provide seed support to develop and pilot new evaluations and interventions that fit the systems-oriented mission.

Training and workforce development are central to the SPORT concept. The center was expected to establish a durable infrastructure for postgraduate education and research training in systems-oriented obesity and chronic disease prevention. In practice, this implies structured training opportunities, mentorship networks, methodological support, and cross-disciplinary learning environments that help trainees and early-career researchers become fluent in systems thinking, computational modeling, and the integration of biological, behavioral, environmental, and policy data. The program is therefore not only about generating findings but also about building a pipeline of researchers who can apply systems methodologies to complex public health problems.

From an administrative and funding standpoint, the award uses the U54 cooperative agreement mechanism, which typically indicates a substantial level of programmatic involvement by the NIH compared with a standard research project grant. The NIH planned to make one award, with a project period of up to five years. The estimated total funding level was $4.25 million in FY2011, reflecting an intention to concentrate resources into a single center of excellence rather than distribute smaller awards across multiple sites. There was no cost sharing or matching requirement listed.

Eligibility was broad and included public and private institutions of higher education, various nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities), and local government entities such as city/township and county governments. The opportunity also listed additional eligible applicants such as eligible federal agencies and regional organizations, indicating flexibility in the kinds of institutions that could lead or participate, so long as they could credibly build the required research, modeling, training, and international partnership components. The FOA was posted September 23, 2010, with an application due date of December 30, 2010, and it was later archived January 30, 2011. The funding opportunity number is RFA-HD-10-001, and it is associated with several CFDA numbers spanning cancer-related research and child health and human development extramural research, reflecting the cross-institute nature of the scientific and public health goals.

Overall, the SPORT Center of Excellence opportunity sought to catalyze a coordinated, systems-driven effort to understand and prevent childhood obesity by combining systems modeling and systems methods with multi-level epidemiology, policy and environmental intervention evaluation, and a strong postgraduate training platform, all built within a U.S.-international partnership and supported through a cooperative agreement structure.

Frequently Asked Questions (FAQs)

What is the SPORT Center of Excellence (U54) funding opportunity?

The Systems Oriented Pediatric Obesity Research and Training (SPORT) Center of Excellence (U54) is a National Institutes of Health (NIH) funding opportunity designed to create a single, high-impact center focused on childhood obesity using a systems science approach. The goal is to build an integrated research and training enterprise that can capture the complexity of pediatric obesity and help forecast or estimate the likely effects of environmental and policy interventions.

Which NIH Institute issued this opportunity?

The opportunity was issued by NIH through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), in partnership with the National Cancer Institute (NCI) and the Office of Behavioral and Social Sciences Research (OBSSR).

What is the central scientific idea behind the SPORT center model?

The SPORT model is based on the premise that pediatric obesity is driven by a complicated web of interacting influences, including biology, behavior, family and community context, the built environment, food systems, and broader social and policy conditions. Instead of treating these drivers as separate risk factors, the center is expected to represent these interactions explicitly using systems-based methods and systems modeling.

What does "systems science approach" mean in the context of this FOA?

In this FOA, a systems science approach refers to transdisciplinary research and methods that can explicitly represent interactions among multiple drivers of obesity across levels (biological, behavioral, environmental, and policy). It also includes systems-based methods and systems modeling intended to help understand obesity etiology and forecast or estimate the effects of interventions and policy changes.

Is this opportunity focused only on individual-level behavior change?

No. The FOA emphasizes moving beyond individual-level explanations and toward multi-level causal models. It highlights epidemiological research linking biological factors to environmental exposures and macro-social determinants.

What kinds of research activities were expected to be included in the center?

The center was expected to support an integrated program that could include (1) etiologic and observational epidemiological research connecting biological factors with environmental and macro-social determinants, and (2) design, evaluation, and testing of environmental and policy approaches to prevent childhood obesity.

What types of interventions or approaches does the FOA highlight?

The FOA highlights environmental and policy approaches such as interventions tied to schools, neighborhoods, food environments, transportation and physical activity infrastructure, marketing environments, and broader policy changes.

Does the FOA include support for pilot or early-stage projects?

Yes. The FOA highlights developmental research funding, meaning the center would provide seed support to develop and pilot new evaluations and interventions that align with the systems-oriented mission.

How important is training in the SPORT Center of Excellence model?

Training and workforce development are central to the SPORT concept. The center was expected to establish durable infrastructure for postgraduate education and research training in systems-oriented obesity and chronic disease prevention, including structured training opportunities, mentorship networks, methodological support, and cross-disciplinary learning environments.

What skills or areas of expertise were emphasized for trainees?

The FOA emphasizes preparing trainees and early-career researchers to become fluent in systems thinking, computational modeling, and integrating biological, behavioral, environmental, and policy data.

Was an international component required?

Yes. A key feature of the program is the expectation that the center would be organized as a partnership between U.S. institutions and international institutions. This structure is intended to support comparisons across countries and build shared research capacity and transferable methods.

Why does the FOA emphasize U.S.-international partnerships?

The FOA reflects the premise that understanding and preventing childhood obesity benefits from comparing contexts, policies, and environments across countries, and from building shared research capacity and methods that can be used across different settings.

What is the funding mechanism used for this opportunity?

The award uses the U54 cooperative agreement mechanism. This typically indicates substantial programmatic involvement by NIH compared with a standard research project grant.

How many awards did NIH plan to make?

NIH planned to make one award, concentrating resources into a single center of excellence.

What was the maximum project period?

The project period could be up to five years.

What was the estimated funding level for this opportunity?

The estimated total funding level was $4.25 million in FY2011.

Is cost sharing or matching required?

No. The FOA did not list any cost sharing or matching requirement.

Who was eligible to apply?

Eligibility was broad and included public and private institutions of higher education, various nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities), and local government entities such as city/township and county governments. The FOA also listed eligible federal agencies and regional organizations.

Are local governments explicitly included as eligible applicants?

Yes. The opportunity explicitly included local government entities such as city/township and county governments among eligible applicants.

Are federal agencies and regional organizations allowed to apply?

Yes. The opportunity listed eligible federal agencies and regional organizations as additional eligible applicants, indicating flexibility in the types of institutions that could lead or participate.

What is the funding opportunity number?

The funding opportunity number is RFA-HD-10-001.

When was the FOA posted and when were applications due?

The FOA was posted on September 23, 2010, and the application due date was December 30, 2010.

Is this FOA still active?

No. The FOA was later archived on January 30, 2011.

Why are multiple CFDA numbers associated with this opportunity?

The opportunity is associated with several CFDA numbers spanning cancer-related research and child health and human development extramural research, reflecting the cross-institute nature of the scientific and public health goals described in the FOA.

What is the overall purpose of the SPORT Center of Excellence opportunity?

Overall, the SPORT opportunity sought to catalyze a coordinated, systems-driven effort to understand and prevent childhood obesity by combining systems modeling and systems methods with multi-level epidemiology, policy and environmental intervention evaluation, and a strong postgraduate training platform, all within a U.S.-international partnership and supported through a cooperative agreement structure.

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