Opportunity Information: Apply for PAR 15 191
Apply for PAR 15 191
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "T2 Translational Research Research Leading to New Health Care Practices, Community Programs and Policies Affecting Older Persons (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Apr 28, 2015 and posted on Apr 28, 2015.
- Applicants must submit their applications by Sep 7, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Public housing authorities/Indian housing authorities Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts For profit organizations other than small businesses County governments Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education State governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
PAR 15-191, titled "T2 Translational Research Leading to New Health Care Practices, Community Programs and Policies Affecting Older Persons (R21)," is an NIH discretionary grant opportunity focused on early-stage, exploratory, and developmental projects that help move what has been proven in clinical studies into routine, real-world use for older adults. The central idea is T2 translational research in aging, meaning research that gathers the practical evidence needed to translate clinical research results into everyday clinical practice and health decision-making. In practice, this often involves taking an intervention that worked under controlled research conditions and adapting it for real health care settings, community organizations, or policy environments, then testing whether it remains effective, feasible, scalable, and sustainable across different contexts.
The FOA specifically encourages work that results in new or improved health care practices, community programs, and policies that affect older persons, including efforts tied to monitoring and quality improvement. It is explicitly open to both pharmacological and non-pharmacological approaches aimed at preventing or treating major health issues in the elderly. The emphasis is less on discovering brand-new basic mechanisms and more on bridging the "implementation gap" that keeps evidence-based interventions from being consistently adopted in clinics, long-term care settings, and community systems. Projects may, for example, examine how to integrate proven treatments into primary care workflows, how to adapt interventions for diverse patient populations, how to improve adherence and follow-up, or how to measure outcomes in ways that better inform clinical and policy decisions.
A wide range of research methods fits under this announcement, reflecting the broad toolkit of T2 research. The FOA lists intervention studies, systematic reviews, meta-analyses, outcomes research, and implementation research as examples, but does not limit applicants to only those approaches. The unifying requirement is that the work supports translation into practice: generating actionable knowledge about effectiveness in real settings, delivery strategies, barriers and facilitators to uptake, quality improvement approaches, or the evidence base needed to shape programs and policies serving older adults.
This opportunity uses the NIH R21 mechanism, which is designed for exploratory and developmental studies that may be higher-risk or earlier in the evidence pipeline than a full-scale effectiveness or implementation trial. The award ceiling listed for this FOA is $200,000, and the estimated total funding is $1,000,000. There is no cost-sharing or matching requirement.
Eligibility is broad and includes many types of U.S.-based organizations and governments. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with or without 501(c)(3) status, for-profit organizations (other than small businesses), small businesses, and a variety of government entities such as state, county, city/township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The FOA also explicitly includes tribal governments and tribal organizations, as well as a range of mission-focused institutions and community-linked entities such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and Asian American Native American Pacific Islander Serving Institutions, along with faith-based and community-based organizations and U.S. territories or possessions. Foreign organizations and foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible; foreign components are not allowed under NIH policy as referenced in the announcement.
Administratively, the opportunity is issued by the National Institutes of Health and is categorized under CFDA 93.866 (Aging Research). It was posted and created on April 28, 2015, with an original and current closing date of September 7, 2018, and an archive date of October 8, 2018, meaning it is no longer open for application. The full announcement was made available through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PAR-15-191.html, and the listed point of contact for access or linking issues is the NIH Office of Extramural Research Webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs) - PAR-15-191 (R21)
What is PAR-15-191?
PAR-15-191 is an NIH discretionary funding opportunity titled "T2 Translational Research Leading to New Health Care Practices, Community Programs and Policies Affecting Older Persons (R21)." It focuses on early-stage, exploratory, and developmental research intended to move findings that have already been proven in clinical studies into routine, real-world use for older adults.
What does "T2 translational research" mean in this FOA?
In this announcement, T2 translational research in aging refers to research that generates practical, actionable evidence needed to translate clinical research results into everyday clinical practice and health decision-making. The emphasis is on closing the "implementation gap" between what works in controlled studies and what is actually adopted consistently in real health care, community, and policy settings serving older persons.
What kinds of outcomes is this FOA trying to produce?
The FOA encourages projects that result in new or improved health care practices, community programs, and policies affecting older persons. It also explicitly welcomes work tied to monitoring and quality improvement, as long as the work supports translation into practice.
Is this opportunity about basic science or discovering new mechanisms?
No. The emphasis is less on discovering brand-new basic mechanisms and more on bridging the implementation gap by adapting and testing interventions for real-world delivery and decision-making in settings relevant to older adults.
What types of interventions are allowed (pharmacological vs. non-pharmacological)?
The FOA is explicitly open to both pharmacological and non-pharmacological approaches aimed at preventing or treating major health issues in the elderly, as long as the project is focused on translating proven clinical study results into routine use.
What are examples of project topics that fit PAR-15-191?
Based on the description provided, examples include projects that adapt an intervention that worked in controlled research conditions for use in real health care settings, community organizations, or policy environments, and then test whether it remains effective, feasible, scalable, and sustainable across different contexts. The FOA also mentions work such as integrating proven treatments into primary care workflows, adapting interventions for diverse patient populations, improving adherence and follow-up, and measuring outcomes in ways that better inform clinical and policy decisions.
What research methods does the FOA encourage?
The FOA lists intervention studies, systematic reviews, meta-analyses, outcomes research, and implementation research as examples of approaches that may fit. It does not limit applicants to only these methods; the key requirement is that the work supports translation into practice by generating actionable knowledge for real-world use.
What is the NIH activity code or grant mechanism used?
This opportunity uses the NIH R21 mechanism, which is designed for exploratory and developmental studies. R21 projects may be higher-risk or earlier in the evidence pipeline than a full-scale effectiveness or implementation trial.
What is the maximum award amount mentioned for this FOA?
The award ceiling listed for this FOA is $200,000.
How much total funding was estimated for this opportunity?
The estimated total funding is $1,000,000.
Is cost-sharing or matching required?
No. The FOA states there is no cost-sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad and includes many types of U.S.-based organizations and governments. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with or without 501(c)(3) status, for-profit organizations (other than small businesses), small businesses, and multiple government entities such as state, county, and city/township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities.
Are tribal governments and tribal organizations eligible?
Yes. The FOA explicitly includes tribal governments and tribal organizations among eligible applicants.
Are mission-focused and community-linked institutions included in eligibility?
Yes. The FOA explicitly references a range of mission-focused institutions and community-linked entities, including HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and Asian American Native American Pacific Islander Serving Institutions, along with faith-based and community-based organizations and U.S. territories or possessions.
Are foreign organizations eligible to apply?
No. Foreign organizations and foreign institutions are not eligible to apply.
Can a U.S. organization include a non-U.S. component or foreign component?
No. The information provided states that non-U.S. components of U.S. organizations are not eligible and that foreign components are not allowed under NIH policy as referenced in the announcement.
Which federal agency issued this opportunity?
The opportunity was issued by the National Institutes of Health (NIH).
What is the CFDA number associated with this FOA?
The FOA is categorized under CFDA 93.866 (Aging Research).
When was PAR-15-191 posted?
The opportunity was posted and created on April 28, 2015.
What was the application closing date, and is it still open?
The original and current closing date listed is September 7, 2018. The archive date is October 8, 2018. Based on these dates, the opportunity is no longer open for application.
Where can the full announcement be found?
The full announcement was made available through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PAR-15-191.html.
Who is the listed contact for access or linking issues?
The listed point of contact for access or linking issues is the NIH Office of Extramural Research Webmaster at FBOWebmaster@OD.NIH.GOV.
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