Opportunity Information: Apply for PAS 11 281
Apply for PAS 11 281
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "T2 Translational Research Research leading to new health care practices, community programs and policies affecting older persons (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Jul 25, 2011 and posted on Jul 25, 2011.
- Applicants must submit their applications by Sep 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Private institutions of higher education Independent school districts State governments Public and State controlled institutions of higher education For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses City or township governments Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) County governments Special district governments Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply.
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Opportunity Summary:
This National Institutes of Health (NIH) funding opportunity (PAS-11-281) supports exploratory and developmental research using the R21 mechanism focused on T2 translational research in aging. The core purpose is to move findings that already exist from clinical studies into real-world use by developing, testing, adapting, and evaluating practical ways to implement effective interventions in everyday clinical care and routine health decision-making. Rather than funding early-stage discovery science, the emphasis is on the "how" of translation: figuring out what it takes for proven or promising approaches to work across different care settings and populations of older adults, and generating the evidence needed to support wider adoption through health care practices, community programs, and policy changes.
The opportunity specifically targets research that can lead to new or improved health care practices, community-based programs, and policies that affect older persons, including work that strengthens monitoring and quality improvement. It is intentionally broad regarding intervention type, welcoming both pharmacological and non-pharmacological approaches aimed at preventing or treating key health issues in the elderly. In practical terms, projects might focus on adapting an intervention that performed well in a controlled clinical trial so it can be delivered in primary care, long-term care, home health, community clinics, or other real-world environments, and then evaluating whether it remains effective, feasible, and acceptable when implemented under routine conditions.
T2 translational research is defined in the announcement as research designed to gather the information needed to develop or evaluate methods for translating clinical study results into everyday practice. The FOA highlights several acceptable methodological approaches, including intervention studies, systematic reviews, meta-analyses, outcomes research, and implementation research. This signals that applicants can propose a range of designs, from testing strategies to improve uptake of evidence-based care, to synthesizing existing evidence to inform practice guidelines, to studying real-world outcomes and service delivery. The overarching expectation is that the work will reduce the gap between what research has shown can work and what actually happens in health care and community settings serving older adults.
The award is a discretionary grant with an award ceiling of $200,000, and it does not require cost sharing or matching. The program falls under CFDA 93.866 (Aging Research). The FOA was posted July 25, 2011, and the last listed closing date was September 7, 2014, with an archive date of October 8, 2014, meaning it is no longer an active competition but remains useful as a reference for NIH priorities and the types of projects that were sought under this mechanism.
Eligibility is expansive and includes many domestic U.S. applicant types such as public and private institutions of higher education, state and local governments, independent school districts, small businesses, for-profit organizations (other than small businesses), and nonprofit organizations with or without 501(c)(3) status. It also explicitly includes a wide range of additional eligible applicants such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribal governments and Tribal organizations, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, regional organizations, and U.S. territories or possessions. Importantly, non-U.S. entities (foreign institutions) are eligible to apply, and non-U.S. components of U.S. organizations are also eligible, reflecting NIH openness to internationally relevant translational work in aging when aligned with program goals.
The sponsoring agency is NIH, and the full announcement was available through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PAS-11-281.html. For technical issues accessing or linking to the announcement, the listed contact was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: NIH PAS-11-281 (R21) T2 Translational Research in Aging
What is this funding opportunity?
This is a National Institutes of Health (NIH) funding opportunity announcement (FOA) identified as PAS-11-281. It supports exploratory and developmental research in aging using the R21 grant mechanism, with a specific focus on T2 translational research.
What is the main goal of PAS-11-281?
The main goal is to move findings that already exist from clinical studies into real-world use. The FOA emphasizes developing, testing, adapting, and evaluating practical ways to implement effective interventions in everyday clinical care and routine health decision-making for older adults.
What does "T2 translational research" mean in this FOA?
In this announcement, T2 translational research is defined as research designed to gather the information needed to develop or evaluate methods for translating clinical study results into everyday practice.
Is this FOA meant to fund basic or early-stage discovery science?
No. The emphasis is not on early-stage discovery science. Instead, it focuses on the "how" of translation: what it takes for proven or promising approaches to work across different care settings and populations of older adults, and what evidence is needed to support broader adoption.
What types of outcomes or impacts is the FOA trying to achieve?
The FOA targets research that can lead to new or improved health care practices, community-based programs, and policies affecting older persons. It also includes work that strengthens monitoring and quality improvement.
What kinds of interventions are in scope?
The opportunity is intentionally broad regarding intervention type. It welcomes both pharmacological and non-pharmacological approaches aimed at preventing or treating key health issues in older adults.
What are examples of the kinds of projects that fit this FOA?
Projects might adapt an intervention that performed well in a controlled clinical trial so it can be delivered in real-world environments such as primary care, long-term care, home health, or community clinics, and then evaluate whether it remains effective, feasible, and acceptable under routine conditions.
What research methods or study approaches does the FOA allow?
The FOA highlights multiple acceptable approaches, including intervention studies, systematic reviews, meta-analyses, outcomes research, and implementation research.
Does the FOA support implementation research specifically?
Yes. Implementation research is explicitly listed as an acceptable methodological approach, aligning with the goal of improving uptake of evidence-based practices in real-world settings.
Can applicants propose evidence synthesis projects like systematic reviews or meta-analyses?
Yes. The FOA explicitly includes systematic reviews and meta-analyses among acceptable approaches, signaling that synthesizing existing evidence to inform practice and decision-making is within scope.
What is the overarching expectation for funded work?
The overarching expectation is to reduce the gap between what research has shown can work and what actually happens in health care and community settings that serve older adults.
What grant mechanism does this FOA use?
This FOA uses the NIH R21 mechanism, which supports exploratory and developmental research projects.
What is the maximum award amount for this grant?
The award ceiling listed for this discretionary grant is $200,000.
Is cost sharing or matching required?
No. The FOA states that cost sharing or matching is not required.
What is the CFDA number for this program?
The program is listed under CFDA 93.866, Aging Research.
Is PAS-11-281 still an active funding opportunity?
No. The FOA was posted on July 25, 2011. The last listed closing date was September 7, 2014, and the archive date was October 8, 2014, indicating it is no longer an active competition.
If the FOA is archived, why might it still be useful?
Even though it is not active, it can still serve as a reference for NIH priorities and the types of translational aging projects that were sought under this R21 mechanism.
Who is eligible to apply?
Eligibility is broad and includes many U.S. applicant types such as public and private institutions of higher education, state and local governments, independent school districts, small businesses, for-profit organizations (other than small businesses), and nonprofit organizations with or without 501(c)(3) status.
Are specific types of institutions and organizations explicitly included?
Yes. The FOA explicitly includes HBCUs, Hispanic-serving institutions, Tribal governments and Tribal organizations, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, regional organizations, and U.S. territories or possessions.
Are foreign (non-U.S.) organizations eligible?
Yes. Non-U.S. entities (foreign institutions) are eligible to apply, and non-U.S. components of U.S. organizations are also eligible.
What kinds of settings does the FOA consider "real-world" for translation?
The FOA describes real-world environments such as primary care, long-term care, home health, community clinics, and other everyday clinical care and community settings where older adults receive services and make health decisions.
Which agency sponsors this opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
Where can the full announcement be found?
The full FOA was available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAS-11-281.html
Who was listed as the contact for technical issues with accessing or linking to the announcement?
For technical issues, the listed contact was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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