Opportunity Information: Apply for PAS 10 097
Apply for PAS 10 097
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Technology Based Adherence Interventions for Substance Abusing Populations with HIV (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Feb 16, 2010 and posted on Jan 27, 2010.
- Applicants must submit their applications by May 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $250,000.00 in funding.
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) County governments Public housing authorities/Indian housing authorities Small businesses For profit organizations other than small businesses City or township governments Private institutions of higher education Independent school districts Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Technology Based Adherence Interventions for Substance Abusing Populations with HIV (R01) funding opportunity (PAS 10 097) is a National Institutes of Health initiative led by the National Institute on Drug Abuse (NIDA) to support research that improves adherence to HIV treatment among people who use or abuse substances. The core aim is to develop, refine, and test technology driven interventions that help patients take HIV medications as prescribed and stay connected to care, especially in the real world settings where adherence actually breaks down. Rather than focusing only on clinic based reminders or education, this program emphasizes approaches that operate in naturally occurring timeframes and contexts, meaning interventions that can reach participants during daily life, at the moments when cravings, instability, or competing demands make adherence hardest.
The scientific focus is on determining the efficacy and potency of adherence interventions that rely on technological tools. The announcement explicitly highlights mobile enabling technologies and real time or near real time methods such as Ecological Momentary Assessment (EMA), enhanced Medication Event Monitoring Systems, computer software, portable digital devices, cell phones, and digital assistant type devices. The underlying idea is that technology can do more than send generic reminders; it can measure behavior and context as they occur, detect risk moments, and deliver timely support that is tailored to the individual. Projects are expected to test whether these tools actually improve antiretroviral therapy adherence and related outcomes for substance using populations, including improvements in access to care and sustained engagement with HIV treatment services.
A key feature of the opportunity is its strong encouragement of multidisciplinary teams. NIDA is looking for collaborations that combine social and behavioral science expertise (to understand adherence barriers and behavior change), clinical expertise from medical providers such as physicians and nurses (to ensure interventions align with HIV care realities and patient safety), and technology experts (to build and iterate on devices, software, mobile platforms, and e health components). The goal is not just to invent technology, but to integrate it into interventions that can be delivered in real time and that fit the needs and constraints of people living with HIV who also face substance use related challenges.
This FOA uses the NIH R01 grant mechanism, which is intended for mature, hypothesis driven research projects and typically supports larger scale efficacy testing than exploratory awards. It runs in parallel with a companion announcement of identical scientific scope that uses the R34 mechanism (PAS 10 098), which generally supports pilot or developmental clinical trial work. In practice, the R01 track is positioned for applicants ready to conduct more definitive studies of intervention impact, while the R34 track exists for teams that still need preliminary development, feasibility, or early testing before moving to a full scale trial.
NIDA projected committing up to 1.5 million dollars in total costs in fiscal year 2010 and up to 1.5 million dollars in fiscal year 2011 across this R01 FOA and the companion R34 FOA, with an anticipated total of 6 to 9 new projects funded between the two announcements. The listed award ceiling in the source data is 250,000, and the opportunity specifies that there is no cost sharing or matching requirement, which lowers the barrier for organizations that do not have large unrestricted funds to contribute.
Eligibility is broad and includes many types of institutions and organizations that can credibly carry out HIV and substance use research. Eligible applicants include public and private institutions of higher education, nonprofits with and without 501(c)(3) status, state and local governments (including county, city, township, special district governments, and independent school districts), small businesses and other for profit organizations, public housing authorities and Indian housing authorities, and a wide range of tribal entities including federally recognized tribal governments and other tribal organizations. The FOA also explicitly includes faith based and community based organizations, historically underserved institution types such as HBCUs, Hispanic serving institutions, Alaska Native and Native Hawaiian serving institutions, and tribally controlled colleges and universities, along with U.S. territories and possessions. Notably, the eligibility list also includes non domestic entities (foreign organizations) and regional organizations, reflecting an openness to international or cross regional collaborations when appropriate to the research goals.
From an administrative standpoint, the opportunity is classified as a discretionary grant under the NIH funding instrument, aligned with the Drug Abuse and Addiction Research Programs CFDA number 93.279. Key dates in the listing include a posted date of January 27, 2010, an original closing date of September 7, 2012, and a current closing date shown as May 7, 2011, with an archive date of June 7, 2011. The agency contact for technical access issues is the NIH Office of Extramural Research webmaster (FBOWebmaster@OD.NIH.GOV), and the full announcement was hosted via the NIH grants guide page linked in the source data.
In plain terms, this grant opportunity is about building and rigorously testing practical, technology enabled ways to help people living with HIV who also struggle with substance use take their medications consistently and stay connected to care, using tools that can track and respond to real life conditions as they unfold. It prioritizes interventions that are measurable, time sensitive, and deployable outside the clinic, and it expects strong collaboration between behavioral science, clinical care, and technology development so that what is built is both scientifically credible and usable in everyday life.
FAQs: Technology Based Adherence Interventions for Substance Abusing Populations with HIV (R01) (PAS 10 097)
What is the PAS 10 097 funding opportunity?
PAS 10 097 is a National Institutes of Health (NIH) funding opportunity led by the National Institute on Drug Abuse (NIDA) to support research that improves adherence to HIV treatment among people who use or abuse substances. It uses the NIH R01 grant mechanism.
What is the overall goal of this grant program?
The core aim is to develop, refine, and test technology-driven interventions that help people living with HIV who also face substance use challenges take antiretroviral therapy as prescribed and stay connected to HIV care. The emphasis is on approaches that work in real-world settings and reach people during daily life when adherence tends to break down.
Who is the target population for the research?
The target population is substance-abusing or substance-using individuals who are living with HIV, particularly those who experience adherence difficulties and challenges staying engaged in HIV treatment services.
What kinds of interventions does the FOA prioritize?
The FOA prioritizes technology-enabled adherence interventions that operate in naturally occurring timeframes and contexts, meaning they can assess, detect, and respond to adherence risks as people go about their daily lives rather than relying only on clinic-based reminders or education.
What types of technology are specifically highlighted as relevant?
The announcement explicitly highlights mobile enabling technologies and real-time or near real-time methods such as Ecological Momentary Assessment (EMA), enhanced Medication Event Monitoring Systems, computer software, portable digital devices, cell phones, and digital assistant-type devices.
Is this grant only about sending medication reminders?
No. The FOA emphasizes that technology should do more than deliver generic reminders. The intended approach is to measure behavior and context as they occur, detect high-risk moments, and deliver timely, tailored support to the individual.
What outcomes are projects expected to improve?
Projects are expected to test whether technology-based tools improve antiretroviral therapy adherence and related outcomes for substance-using populations, including improved access to care and sustained engagement with HIV treatment services.
What kind of research design is this opportunity best suited for?
This FOA uses the NIH R01 mechanism, which is intended for mature, hypothesis-driven research projects and typically supports larger-scale efficacy testing than exploratory awards.
How is the R01 (PAS 10 097) different from the companion R34 (PAS 10 098)?
The companion announcement (PAS 10 098) uses the R34 mechanism and has identical scientific scope, but it generally supports pilot or developmental clinical trial work. The R01 track is positioned for applicants ready to conduct more definitive studies of intervention impact, while the R34 track is for teams that still need preliminary development, feasibility work, or early testing.
Does the FOA encourage multidisciplinary teams?
Yes. NIDA strongly encourages multidisciplinary collaborations combining (1) social and behavioral science expertise, (2) clinical expertise from providers such as physicians and nurses, and (3) technology expertise to build and iterate on devices, software, mobile platforms, and e-health components.
Which NIH institute is leading this initiative?
The initiative is led by the National Institute on Drug Abuse (NIDA) under NIH.
What is the funding mechanism and instrument type?
The mechanism is NIH R01. The opportunity is classified as a discretionary grant under the NIH funding instrument.
Is there a cost sharing or matching requirement?
No. The opportunity specifies that there is no cost sharing or matching requirement.
How much funding was NIDA projecting for this FOA and its companion FOA?
NIDA projected committing up to $1.5 million in total costs in fiscal year 2010 and up to $1.5 million in total costs in fiscal year 2011 across this R01 FOA (PAS 10 097) and the companion R34 FOA (PAS 10 098).
How many awards were anticipated?
The listing anticipated a total of 6 to 9 new projects funded between the two announcements (the R01 and the companion R34).
Is there an award ceiling listed?
Yes. The source data lists an award ceiling of 250,000.
What CFDA number is associated with this opportunity?
The CFDA number listed is 93.279 (Drug Abuse and Addiction Research Programs).
Who is eligible to apply?
Eligibility is broad and includes public and private institutions of higher education; nonprofits with and without 501(c)(3) status; state and local governments (including county, city, township, special district governments, and independent school districts); small businesses and other for-profit organizations; public housing authorities and Indian housing authorities; tribal entities including federally recognized tribal governments and other tribal organizations; and faith-based and community-based organizations.
Are historically underserved institutions included in eligibility?
Yes. The FOA explicitly includes institution types such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and tribally controlled colleges and universities.
Are U.S. territories and possessions eligible?
Yes. U.S. territories and possessions are included in the eligibility description.
Are foreign organizations allowed to apply?
Yes. The eligibility list includes non-domestic entities (foreign organizations) and regional organizations.
What are the key dates shown in the listing?
The listing includes a posted date of January 27, 2010; an original closing date of September 7, 2012; a current closing date shown as May 7, 2011; and an archive date of June 7, 2011.
Who should be contacted for technical access issues?
The agency contact for technical access issues is the NIH Office of Extramural Research webmaster at FBOWebmaster@OD.NIH.GOV.
Where was the full announcement hosted?
The full announcement was hosted via the NIH Grants Guide page linked in the source data.
What does "real-world settings" mean in this FOA?
In this FOA, real-world settings refers to adherence support that functions outside the clinic and can reach participants during everyday life, including moments when cravings, instability, or competing demands make adherence most difficult.
What does the FOA mean by "naturally occurring timeframes and contexts"?
It means the interventions are designed to operate and deliver support at the times and in the situations where adherence challenges occur in day-to-day life, including real-time or near real-time assessment and response.
What is the plain-language purpose of this funding opportunity?
It is about building and rigorously testing practical, technology-enabled ways to help people living with HIV who also struggle with substance use take their medications consistently and stay connected to care, using tools that can track and respond to real-life conditions as they unfold.
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| Funding Opportunity |
|---|
| Technology Based Adherence Interventions for Substance Abusing Populations with HIV (R34) Apply for PAS 10 098 Funding Number: PAS 10 098 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Chronic Co Morbid Conditions in HIV U.S. Adults on Highly Effective Anti Retroviral Therapy (R01) Apply for RFA NR 10 001 Funding Number: RFA NR 10 001 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Chronic Co Morbid Conditions in HIV U.S. Adults on Highly Effective Anti Retroviral Therapy (R21) Apply for RFA NR 10 002 Funding Number: RFA NR 10 002 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows (Parent F31) Apply for PA 10 108 Funding Number: PA 10 108 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Comprehensive Partnerships to Reduce Cancer Health Disparities (Limited Competition U54) Apply for RFA CA 10 503 Funding Number: RFA CA 10 503 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Advancing Palliative Care Research for Children Facing Life Limiting Conditions (R21) Apply for RFA NR 10 007 Funding Number: RFA NR 10 007 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Advancing Palliative Care Research for Children Facing Life Limiting Conditions (R01) Apply for RFA NR 10 006 Funding Number: RFA NR 10 006 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Common Pathogenetic Mechanisms of Lung Cancer and COPD (R01) Apply for RFA HL 11 002 Funding Number: RFA HL 11 002 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Collaborative Clinical Trials in Drug Abuse (Collaborative R01) Apply for PAR 10 099 Funding Number: PAR 10 099 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Strategic Partnering to Evaluate Cancer Signatures SPECS II (U01) Apply for PAR 10 126 Funding Number: PAR 10 126 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Epigenetic Factors Associated with Symptoms and Complications of Chronic Disorders (Competitive Revision R01) Apply for RFA NR 10 005 Funding Number: RFA NR 10 005 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Epigenetic Factors Associated with Symptoms and Complications of Chronic Disorders (R01) Apply for RFA NR 10 004 Funding Number: RFA NR 10 004 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Abuse Aspects of HIV/AIDS (R03) Apply for PA 10 131 Funding Number: PA 10 131 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Abuse Aspects of HIV/AIDS (R01) Apply for PA 10 129 Funding Number: PA 10 129 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Abuse Aspects of HIV/AIDS (R21) Apply for PA 10 130 Funding Number: PA 10 130 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| The Medical Education Partnership Initiative (MEPI) (R24) Apply for RFA TW 10 008 Funding Number: RFA TW 10 008 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Research Education Program for Laboratory Animal Medicine Veterinarians (R25) Apply for RFA RR 10 002 Funding Number: RFA RR 10 002 Agency: National Institutes of Health Category: Education Health Funding Amount: $224,000 |
| Next Generation Genetic Association Studies (U01) Apply for RFA HL 11 006 Funding Number: RFA HL 11 006 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Exploratory Cancer Prevention Studies Involving Molecular Targets for Bioactive Food Components (R21) Apply for PA 10 088 Funding Number: PA 10 088 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Development of Animal Models and Related Biological Materials For Research (R21) Apply for PA 10 138 Funding Number: PA 10 138 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
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