Opportunity Information: Apply for PAR 10 075
Apply for PAR 10 075
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Technology Development for Protein Modeling (P01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859 Biomedical Research and Research Training.
- This funding opportunity was created on Jan 5, 2010 and posted on Jan 5, 2010.
- Applicants must submit their applications by May 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments For profit organizations other than small businesses State governments Small businesses County governments Private institutions of higher education Native American tribal governments (Federally recognized) Independent school districts.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
Technology Development for Protein Modeling (P01) is an NIH funding opportunity from the National Institute of General Medical Sciences (NIGMS) focused on advancing the state of the art in protein structure prediction. The central goal is technology development: applicants are expected to propose new methods, tools, or approaches that can materially increase the accuracy of comparative (template-based) protein modeling. In practical terms, the opportunity is aimed at projects that tackle key limitations in predicting reliable 3D protein structures when experimental structures are unavailable, especially by improving the computational steps that connect sequence information to structural models.
This opportunity uses the P01 program project grant mechanism, which is specifically intended for coordinated, multi-project research efforts. Rather than supporting a single standalone project, a P01 supports several interdependent projects that are scientifically linked, where working as an integrated program produces clear advantages over funding each project separately. Applicants typically build a cohesive set of projects that share a common theme and mutually reinforce one another, for example by combining algorithm development, benchmarking and validation, data resources, and software engineering or dissemination components into one integrated program. The FOA notes that it runs in parallel with a separate announcement of the same scientific scope that uses the R01 mechanism (PAR-10-076), giving investigators a choice between a single-project R01 approach and a multi-component P01 structure depending on how their research is organized.
Funding levels and the number of awards are not preset. NIGMS indicates that the total amount awarded will depend on the scientific merit of the submitted applications and on the availability of funds in the institute's general funding pool. Because proposed programs can differ widely in scale, complexity, duration, and cost, award sizes and project periods are expected to vary. The FOA also emphasizes that final award decisions will reflect the number, quality, duration, and budgets of the applications received, which is typical language for NIH opportunities where the institute does not commit to a fixed number of awards.
From an administrative standpoint, this is a discretionary grant opportunity in the health funding category and is associated with CFDA number 93.859 (Biomedical Research and Research Training). It does not require cost sharing or matching. The opportunity was posted and created on January 5, 2010, with an original and current closing date of May 7, 2013, and it was archived on June 7, 2013. The funding opportunity number is PAR-10-075, and the sponsoring agency is the National Institutes of Health.
Eligibility is broad and includes many organization types across the public, private, nonprofit, and educational sectors. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with or without 501(c)(3) status (with the noted exclusions), for-profit organizations (including small businesses and other than small businesses), and multiple levels of government such as state, county, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The FOA also lists additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Native American tribal organizations (including both federally recognized and other than federally recognized, as specified), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.
Applicants seeking the full announcement details were directed to the NIH grants guide page for PAR-10-075, and NIH provided contact support through the NIH Office of Extramural Research (OER) webmaster email for technical issues accessing or linking to the announcement.
Frequently Asked Questions (FAQs): Technology Development for Protein Modeling (P01) - PAR-10-075
What is the Technology Development for Protein Modeling (P01) funding opportunity?
Technology Development for Protein Modeling (P01) is an NIH funding opportunity sponsored by the National Institute of General Medical Sciences (NIGMS). It focuses on advancing the state of the art in protein structure prediction, with an emphasis on technology development that improves comparative (template-based) protein modeling accuracy.
Which NIH institute is associated with this opportunity?
The sponsoring NIH institute is the National Institute of General Medical Sciences (NIGMS).
What is the main scientific goal of this FOA?
The central goal is to develop new technology that can materially increase the accuracy of comparative (template-based) protein modeling. The opportunity targets improvements in computational steps that connect protein sequence information to reliable 3D structural models, particularly when experimental structures are not available.
What kind of work does NIGMS expect applicants to propose?
Applicants are expected to propose new methods, tools, or approaches that improve comparative protein modeling. The emphasis is on technology development that addresses key limitations in predicting reliable 3D protein structures when experimental structures are unavailable.
What grant mechanism does this opportunity use?
This opportunity uses the P01 program project grant mechanism.
What does a P01 program project grant support?
A P01 supports a coordinated, multi-project research effort rather than a single standalone project. It is intended for several interdependent projects that are scientifically linked, where running the work as an integrated program provides clear advantages over funding the projects separately.
How should projects within a P01 be organized?
Projects are expected to be scientifically linked and mutually reinforcing under a common theme. The FOA indicates that applicants typically build a cohesive set of projects that work better together as a program than as separate awards.
What are examples of components that could be included in an integrated P01 program?
The FOA provides examples such as combining algorithm development, benchmarking and validation, data resources, and software engineering or dissemination components into one integrated program.
Is there an alternative NIH mechanism with the same scientific scope?
Yes. The FOA notes it runs in parallel with a separate announcement of the same scientific scope that uses the R01 mechanism (PAR-10-076). This offers investigators a choice between a single-project R01 approach and a multi-component P01 approach depending on how their research is organized.
What is the funding opportunity number for this FOA?
The funding opportunity number is PAR-10-075.
What is the CFDA number associated with this opportunity?
This opportunity is associated with CFDA number 93.859 (Biomedical Research and Research Training).
What funding category is this opportunity listed under?
It is listed in the health funding category.
Is cost sharing or matching required?
No. The FOA states that cost sharing or matching is not required.
How much funding is available and how many awards will be made?
Funding levels and the number of awards are not preset. NIGMS indicates the total amount awarded will depend on scientific merit and the availability of funds in the institute's general funding pool. Award sizes and project periods are expected to vary because programs can differ in scale, complexity, duration, and cost.
What factors influence final NIH award decisions for this opportunity?
The FOA emphasizes that final award decisions will reflect the number, quality, duration, and budgets of the applications received, along with scientific merit and the availability of funds.
When was this opportunity posted?
The opportunity was posted and created on January 5, 2010.
What was the closing date for applications?
The original and current closing date listed is May 7, 2013.
Is this funding opportunity still open?
No. The opportunity was archived on June 7, 2013.
Who is eligible to apply?
Eligibility is broad and includes many organization types across public, private, nonprofit, and educational sectors, as well as multiple levels of government and other specified entities.
Are higher education institutions eligible?
Yes. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education.
Are nonprofit organizations eligible?
Yes. Nonprofits with or without 501(c)(3) status are eligible (with noted exclusions referenced in the FOA).
Are for-profit organizations eligible?
Yes. For-profit organizations are eligible, including small businesses and other than small businesses.
Are government entities eligible?
Yes. Eligible government applicants include state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities.
Are minority-serving institutions included in the eligible applicant types?
Yes. The FOA lists categories including Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Are tribal organizations eligible?
Yes. The FOA includes Native American tribal organizations, including both federally recognized and other than federally recognized organizations (as specified).
Are faith-based or community-based organizations eligible?
Yes. The FOA lists faith-based or community-based organizations among the eligible applicant categories.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are listed as eligible applicants.
Are federal agencies eligible?
Yes. The FOA lists eligible federal agencies among the eligible applicant categories.
Where can applicants find the full FOA announcement details?
Applicants were directed to the NIH grants guide page for PAR-10-075 for full announcement details.
Who should be contacted for technical issues accessing or linking to the announcement?
NIH provided contact support through the NIH Office of Extramural Research (OER) webmaster email for technical issues related to accessing or linking to the announcement.
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