Opportunity Information: Apply for PAR 10 076
Apply for PAR 10 076
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Technology Development for Protein Modeling (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859 Biomedical Research and Research Training.
- This funding opportunity was created on Jan 5, 2010 and posted on Jan 5, 2010.
- Applicants must submit their applications by Jan 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: For profit organizations other than small businesses Public and State controlled institutions of higher education Private institutions of higher education City or township governments Independent school districts Small businesses Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) County governments State governments Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Technology Development for Protein Modeling (R01) funding opportunity (PAR-10-076) is a discretionary NIH grant program administered through the National Institute of General Medical Sciences (NIGMS). Its central goal is to support research projects that create new technologies capable of substantially improving the accuracy of comparative (template-based) protein structure modeling. In practical terms, the opportunity is aimed at methods development that makes predicted protein structures more reliable when researchers are inferring a protein's 3D shape from related proteins with known structures, which is a foundational technique used across basic biology and biomedical research.
Awards are made using the NIH R01 mechanism, meaning applicants are expected to propose a clearly defined, hypothesis-driven or technology-driven research plan suitable for a standard, investigator-initiated research project. This R01 announcement is explicitly paired with a parallel opportunity of the same scientific scope that uses the P01 mechanism (PAR-10-075), which is generally designed for larger, multi-project program grants. Applicants whose work fits a single cohesive research project would typically align with the R01, while larger coordinated efforts might consider the P01 counterpart.
The program does not set a fixed award size, project period, or number of awards in advance. Instead, NIH indicates that budgets, durations, and the total number of funded projects will vary depending on what is proposed and on the usual NIH considerations: scientific merit, scope, requested costs, and overall application quality. There is no cost sharing or matching requirement, which is consistent with many NIH research grant opportunities.
Eligibility is broad and includes a wide range of domestic and non-domestic organizations. Eligible applicants include public and private institutions of higher education, for-profit organizations (including small businesses), nonprofits with or without 501(c)(3) status, and multiple categories of government entities (city/township, county, state, special district). The announcement also explicitly includes groups such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian Serving Institutions, tribal governments and tribal organizations, faith-based or community-based organizations, U.S. territories or possessions, regional organizations, and foreign organizations (non-U.S. entities). In short, NIH is signaling that it wants the strongest technology-development ideas regardless of institutional type, as long as the applicant organization is eligible and can carry out the work.
From an administrative standpoint, the opportunity was posted on January 5, 2010, with an original and current closing date of January 7, 2013, and an archive date of February 7, 2013, meaning it is no longer open for new submissions under this specific announcement. The activity aligns with CFDA 93.859 (Biomedical Research and Research Training), and the full archived announcement was hosted through the NIH Grants Guide. For access issues or broken links, the listed point of contact is the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV).
Frequently Asked Questions (FAQs)
What is the Technology Development for Protein Modeling (R01) opportunity (PAR-10-076)?
PAR-10-076 is an NIH discretionary grant opportunity using the R01 mechanism, administered through the National Institute of General Medical Sciences (NIGMS). It supports research projects focused on developing new technologies to substantially improve the accuracy of comparative (template-based) protein structure modeling.
Which NIH institute administers this funding opportunity?
The program is administered by the National Institute of General Medical Sciences (NIGMS).
What is the main scientific goal of this program?
The central goal is to support methods and technology development that makes comparative (template-based) protein structure predictions more accurate and reliable, especially when inferring a protein's 3D structure from related proteins with known structures.
What type of protein modeling is specifically targeted?
This opportunity specifically targets comparative (template-based) protein structure modeling (also described as template-based modeling).
What is meant by "comparative (template-based) protein structure modeling" in this context?
In this context, it refers to predicting a protein's 3D shape by using one or more related proteins with experimentally determined structures as templates, and improving the technology so those predictions are more reliable.
What grant mechanism is used for awards under PAR-10-076?
Awards are made using the NIH R01 mechanism, intended for a clearly defined, investigator-initiated research project with a hypothesis-driven or technology-driven research plan.
Is this opportunity connected to any other NIH funding announcement?
Yes. PAR-10-076 is explicitly paired with a parallel opportunity of the same scientific scope that uses the P01 mechanism: PAR-10-075.
How should an applicant decide between the R01 (PAR-10-076) and the P01 (PAR-10-075)?
Based on the description provided, projects that fit a single cohesive research effort would typically align with the R01, while larger coordinated efforts may be more appropriate for the P01 counterpart.
Does the program set a fixed award size?
No. The program does not set a fixed award size in advance. Budgets vary depending on what is proposed and standard NIH considerations such as scientific merit, scope, requested costs, and overall application quality.
Does the program set a fixed project period (duration)?
No. The program does not set a fixed project period in advance. Project durations vary depending on what is proposed and NIH review and funding considerations.
Is the number of awards predetermined?
No. NIH indicates the total number of funded projects will vary depending on the applications received, their scientific merit, and other typical NIH considerations.
Are cost sharing or matching funds required?
No. There is no cost sharing or matching requirement for this opportunity.
Who is eligible to apply?
Eligibility is broad and includes domestic and non-domestic organizations. Eligible applicants include public and private institutions of higher education, for-profit organizations (including small businesses), nonprofit organizations (with or without 501(c)(3) status), and multiple categories of government entities.
Are foreign (non-U.S.) organizations eligible to apply?
Yes. The announcement explicitly includes foreign organizations (non-U.S. entities) among eligible applicants.
What types of U.S. government entities are listed as eligible?
Multiple categories of government entities are listed, including city/township, county, state, and special district governments.
Are minority-serving institutions mentioned as eligible?
Yes. The eligibility description explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, and tribally controlled colleges and universities, among others.
Are tribal entities included in the eligible applicant types?
Yes. The opportunity explicitly includes tribal governments and tribal organizations, as well as tribally controlled colleges and universities.
Are Alaska Native and Native Hawaiian Serving Institutions included?
Yes. Alaska Native and Native Hawaiian Serving Institutions are explicitly listed as eligible.
Are faith-based or community-based organizations eligible?
Yes. Faith-based and community-based organizations are explicitly included among eligible applicants.
Are U.S. territories or possessions included in the eligibility list?
Yes. U.S. territories or possessions are explicitly included.
Are regional organizations eligible?
Yes. Regional organizations are explicitly included among eligible applicants.
When was this funding opportunity posted?
The opportunity was posted on January 5, 2010.
What was the closing date for PAR-10-076?
The original and current closing date listed is January 7, 2013.
Is PAR-10-076 still open for new submissions?
No. The announcement has an archive date of February 7, 2013, and is no longer open for new submissions under this specific announcement.
What is the archive date, and what does it imply here?
The archive date is February 7, 2013. In this context, it indicates the announcement is archived and not open for new submissions under PAR-10-076.
What CFDA number is associated with this activity?
This activity aligns with CFDA 93.859 (Biomedical Research and Research Training).
Where was the full announcement hosted?
The full archived announcement was hosted through the NIH Grants Guide.
Who should be contacted for access issues or broken links related to the announcement?
For access issues or broken links, the listed point of contact is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
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