Opportunity Information: Apply for RFA DP 10 004

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Translating Research into Healthy Eye and Vision Loss Prevention (U58)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.283 Centers for Disease Control and PreventionInvestigations and Technical Assistance.
  • This funding opportunity was created on Jan 8, 2010 and posted on Jan 5, 2010.
  • Applicants must submit their applications by Mar 12, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $900,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $300,000.00 in funding.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Public nonprofit organizations Private nonprofit organizations For profit organizations Small, minority, and women owned businesses Universities Colleges Research institutions Hospitals Community based organizations Faith based organizations Federally recognized or state recognized American Indian/Alaska Native tribal governments American Indian/Alaska Native tribally designated organizations Alaska Native health corporations Urban Indian health organizations Tribal epidemiology centers State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau) Political subdivisions of States (in consultation with States) A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If you are applying as a bona fide agent of a state or local government, you must provide a letter from the state or local government as documentation of your status. Attach this documentation behind the first page of your application form or for electronic applications, use a PDF file and attach as Other Documents and label as appropriate.
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Opportunity Summary:

Translating Research into Healthy Eye and Vision Loss Prevention (U58) is a CDC cooperative agreement funding opportunity designed to support applied public health research that helps close the real-world gap between what evidence-based eye care recommends and what patients actually receive in routine practice. The central idea is not basic science or clinical trials for new treatments, but practical, implementation-focused research that examines why proven eye care and vision loss prevention strategies are not consistently reaching people, and what can be changed in systems and services to improve access, quality, and outcomes. Funded projects are expected to move beyond describing disparities and instead use structured research methods to identify actionable barriers and supports that influence delivery of effective and cost-efficient eye care.

A defining feature of this opportunity is the expectation that awardees develop and implement a common research protocol. That means the program is aiming for comparable methods and measures across funded sites so findings can be interpreted together, generalized more confidently, and used to guide public health and health system decision-making. The research emphasis includes both system-level factors (for example, how care is organized, referral pathways, workforce capacity, reimbursement and coverage issues, clinic workflows, availability of specialists, data systems, and coordination between primary care and eye care) and individual-level factors (such as patient knowledge, perceived need, trust, cultural and language barriers, transportation, cost burden, adherence to follow-up, and other practical constraints that affect whether people get timely eye exams and treatment).

The FOA also highlights the use of existing data as a major component of the work. Applicants are expected to analyze available datasets and other real-world information sources to pinpoint where the delivery of eye care breaks down and what factors enable better performance. In practical terms, this could involve leveraging health system records, claims, surveillance and population health datasets, or program data to examine screening uptake, referral completion, treatment adherence, and outcomes tied to preventable vision loss. The goal is to translate evidence into routine practice by clearly mapping the obstacles and the conditions that make high-quality eye care more likely to occur consistently and equitably.

This opportunity was issued under Funding Opportunity Number RFA DP 10 004 and uses the U58 cooperative agreement mechanism, meaning CDC would anticipate substantial involvement with recipients compared with a standard grant, typically through collaboration on protocol development, alignment on measures, and coordinated evaluation expectations. The funding instrument is discretionary and falls under a health activity category. CDC anticipated making three awards, with an estimated total funding amount of $900,000 and an award ceiling of $300,000 per award; there was no stated award floor. No cost sharing or matching was required.

Eligibility was broad and included public and private nonprofit organizations, for-profit organizations (including small, minority-owned, and women-owned businesses), universities and colleges, research institutions, hospitals, community-based and faith-based organizations, and tribal entities (including federally or state recognized American Indian/Alaska Native tribal governments and tribally designated organizations, Alaska Native health corporations, urban Indian health organizations, and tribal epidemiology centers). State and local governments and their bona fide agents were also eligible, including U.S. territories and affiliated jurisdictions listed in the announcement. Applicants applying as a bona fide agent were required to provide documentation (a letter from the relevant state or local government) confirming that status.

Key administrative dates show the announcement was posted January 5, 2010, with an original and final closing date of March 12, 2010, and an archive date of April 11, 2010. The CFDA number associated with the opportunity was 93.283 (CDC Investigations and Technical Assistance). The announcement also noted that a planned teleconference had been cancelled. For assistance accessing the full announcement, the CDC grants contact provided was CDC/PGOTIM at 770-488-2700 or pgotim@cdc.gov.

FAQs: Translating Research into Healthy Eye and Vision Loss Prevention (U58) - CDC (RFA DP 10 004)

What is the purpose of this CDC funding opportunity?

This cooperative agreement supports applied public health research focused on closing the gap between evidence-based eye care recommendations and what patients actually receive in routine practice. The emphasis is on practical, implementation-focused research that identifies actionable barriers and supports within real-world systems and services so that effective, cost-efficient eye care and vision loss prevention strategies are delivered more consistently and equitably.

Is this opportunity for basic science or clinical trials of new treatments?

No. The central focus is not basic science research or clinical trials for new treatments. The work is intended to be implementation-focused, examining why proven strategies are not reaching people and what changes to systems or service delivery could improve access, quality, and outcomes.

What type of research is CDC looking for under this program?

CDC is looking for structured, applied research that goes beyond describing disparities and instead identifies specific, actionable factors that influence whether proven eye care and vision loss prevention strategies are delivered in practice. Projects are expected to study real-world delivery issues and generate findings that can inform public health and health system decision-making.

What does it mean that awardees are expected to develop and implement a common research protocol?

Funded projects are expected to align around a shared research protocol so that methods and measures are comparable across sites. This is intended to make results easier to interpret together, support stronger generalization of findings, and improve the usefulness of the evidence for policy and practice decisions.

What kinds of system-level factors are within the scope of the research?

The announcement highlights system-level factors such as how care is organized, referral pathways, workforce capacity, reimbursement and coverage issues, clinic workflows, availability of specialists, data systems, and coordination between primary care and eye care.

What kinds of individual-level factors are within the scope of the research?

The opportunity also includes individual-level factors that can affect timely eye exams and treatment, including patient knowledge, perceived need, trust, cultural and language barriers, transportation, cost burden, and adherence to follow-up.

How important is the use of existing data in this program?

Using existing data is described as a major component of the work. Applicants are expected to analyze available datasets and other real-world information sources to identify where eye care delivery breaks down and what conditions enable better performance.

What data sources are mentioned as examples for analysis?

Examples include health system records, claims data, surveillance and population health datasets, and program data. These sources could be used to examine screening uptake, referral completion, treatment adherence, and outcomes related to preventable vision loss.

What is the main goal of analyzing these real-world data sources?

The goal is to translate evidence into routine practice by clearly mapping obstacles to high-quality eye care and identifying the conditions that make consistent and equitable delivery more likely.

What is the funding opportunity number and mechanism?

The Funding Opportunity Number is RFA DP 10 004, and it uses the U58 cooperative agreement mechanism.

What does a U58 cooperative agreement imply about CDC involvement?

A U58 is a cooperative agreement, meaning CDC anticipated substantial involvement compared with a standard grant. The announcement notes involvement such as collaboration on protocol development, alignment on measures, and coordinated evaluation expectations.

How many awards did CDC anticipate making and what was the total funding amount?

CDC anticipated making three awards, with an estimated total funding amount of $900,000.

What was the maximum award amount per recipient?

The award ceiling was $300,000 per award.

Was there a minimum award amount stated?

No award floor was stated in the information provided.

Was cost sharing or matching required?

No. The announcement stated that no cost sharing or matching was required.

Who was eligible to apply?

Eligibility was broad and included public and private nonprofit organizations, for-profit organizations (including small, minority-owned, and women-owned businesses), universities and colleges, research institutions, hospitals, community-based and faith-based organizations, tribal entities (including federally or state recognized American Indian/Alaska Native tribal governments and tribally designated organizations, Alaska Native health corporations, urban Indian health organizations, and tribal epidemiology centers), and state and local governments and their bona fide agents. U.S. territories and affiliated jurisdictions listed in the announcement were also eligible.

What is a "bona fide agent" and what documentation was required?

An applicant applying as a bona fide agent of a state or local government was required to provide documentation confirming that status, specifically a letter from the relevant state or local government.

When was the announcement posted and when did it close?

The announcement was posted on January 5, 2010. The original and final closing date was March 12, 2010.

What were the archive details for this opportunity?

The archive date listed was April 11, 2010.

What CFDA number was associated with this funding opportunity?

The CFDA number associated with the opportunity was 93.283 (CDC Investigations and Technical Assistance).

Was there an informational teleconference for applicants?

The announcement noted that a planned teleconference had been cancelled.

Who should be contacted for help accessing the full announcement?

The CDC grants contact listed for assistance accessing the full announcement was CDC/PGOTIM at 770-488-2700 or pgotim@cdc.gov.

What type of funding instrument category was this?

The funding instrument was discretionary and fell under a health activity category.

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