Opportunity Information: Apply for PA 07 181

  • The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "The Influence of Religiosity and Spirituality on Health Risk Behaviors in Children and Adolescents (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.361 Nursing Research 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Dec 5, 2008 and posted on Dec 15, 2006.
  • Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Small businesses State governments Special district governments Independent school districts County governments.
  • Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
Apply for PA 07 181

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Opportunity Summary:

The NIH funding opportunity titled "The Influence of Religiosity and Spirituality on Health Risk Behaviors in Children and Adolescents (R01)" (Funding Opportunity Number PA-07-181) supports research that looks closely at how religiosity develops in young people, how it is passed along within families and communities, and how it can shape behaviors linked to HIV risk during childhood and adolescence. The central goal is to understand the pathways through which religious and spiritual beliefs, practices, and environments affect early sexual behavior and the use of alcohol or other drugs, especially when those behaviors increase the likelihood of HIV transmission. A key feature of the announcement is that it treats religiosity as potentially protective in some settings and potentially harmful in others, encouraging applicants to examine both positive and negative effects rather than assuming religiosity is automatically beneficial or automatically risky.

The science focus is on mechanisms, mediators, and moderators. In practical terms, this means the NIH is looking for studies that do more than show a simple correlation between religiosity and behavior. Proposed projects are expected to investigate how religiosity exerts influence (mechanisms), what factors explain the relationship (mediators, such as peer norms, parental monitoring, moral beliefs, stigma, social support, or mental health), and under what conditions the relationship changes (moderators, such as age, gender, sexual orientation, race and ethnicity, socioeconomic status, family structure, denomination or tradition, level of community religious involvement, or local cultural context). The announcement highlights intergenerational transmission, so strong applications would typically consider how beliefs and practices are communicated from parents or caregivers to children, how youth interpret and adopt those messages, and how family and community religious life intersects with development during adolescence.

The FOA also stresses the importance of considering the increasingly pluralistic religious landscape in the United States. Rather than focusing narrowly on a single tradition, it invites research that is attentive to the diversity of religions and belief systems present in the U.S., and by extension the different norms, teachings, and community practices that may influence adolescent decision-making. This emphasis implies interest in culturally grounded and context-sensitive research designs, including studies that can distinguish between different dimensions of religiosity (for example, affiliation, attendance, private practices, personal salience, spirituality, doctrinal beliefs, and participation in youth programs) and how those dimensions might relate differently to sexual initiation, condom use, number of partners, substance use, co-occurring risk behaviors, and other HIV-related outcomes.

In terms of funding structure, this opportunity uses the NIH Research Project Grant (R01) mechanism, which is intended for full-scale, hypothesis-driven research projects that can support substantial, multi-year work. The announcement notes it runs in parallel with companion FOAs of identical scientific scope that use other mechanisms: an R03 small research grant and an R21 exploratory/developmental grant. Budgets and project periods are not set to a single fixed amount because NIH expects proposals to vary in size and complexity; the number of awards and total dollars ultimately depend on the number of applications received, their scientific merit, and requested costs and duration.

Eligibility is broad and includes many types of institutions and organizations. Eligible applicants include public and private institutions of higher education, nonprofits with or without 501(c)(3) status, small businesses and other for-profit organizations (other than small businesses), state governments, U.S. territories or possessions, and a range of tribal entities (federally recognized tribes, other tribal governments, and tribally designated organizations). The FOA also explicitly lists and welcomes participation from organizations such as Hispanic-serving institutions, HBCUs, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, regional organizations, and eligible federal agencies. Importantly, faith-based and community-based organizations may apply, and foreign (non-U.S.) entities are also eligible, which signals openness to international perspectives or comparative work, so long as the research fits the FOA focus.

Administrative details in the source listing show the opportunity is a discretionary grant under NIH, with activity areas spanning education, health, income security, and social services, and it is associated with CFDA program numbers that include alcohol research, nursing research, and child health and human development extramural research (93.273, 93.361, 93.865). The FOA does not require cost sharing or matching. The opportunity was posted December 15, 2006, and used multiple receipt dates rather than a single deadline; it was later archived August 5, 2009. For full details, NIH directed applicants to the complete announcement page (grants.nih.gov) and provided an NIH Office of Extramural Research webmaster contact for access or linking issues.

Overall, this grant announcement is aimed at building a clearer, evidence-based understanding of when and how religiosity shapes adolescent health risk behaviors connected to HIV transmission, with special attention to the complex social and developmental processes that link family, belief, identity, and behavior. It encourages rigorous research designs that can unpack causal pathways and contextual differences, rather than treating religiosity as a single uniform factor.

FAQs: The Influence of Religiosity and Spirituality on Health Risk Behaviors in Children and Adolescents (R01) (PA-07-181)

What is this NIH funding opportunity?

This is an NIH Funding Opportunity Announcement (FOA) titled "The Influence of Religiosity and Spirituality on Health Risk Behaviors in Children and Adolescents (R01)." The Funding Opportunity Number is PA-07-181, and it uses the NIH Research Project Grant (R01) mechanism.

What is the main purpose of the FOA?

The FOA supports research to understand how religiosity and spirituality develop in children and adolescents, how they are transmitted within families and communities, and how they shape behaviors that affect HIV risk. The central emphasis is on pathways linking religious/spiritual beliefs, practices, and environments to early sexual behavior and alcohol or other drug use when those behaviors increase the likelihood of HIV transmission.

What kinds of youth behaviors are in scope?

The scope includes HIV-related health risk behaviors during childhood and adolescence, with specific attention to early sexual behavior and the use of alcohol or other drugs. Examples of outcomes mentioned include sexual initiation, condom use, number of partners, substance use, and co-occurring risk behaviors.

Does the FOA assume religiosity is always protective?

No. A key feature of the FOA is that it treats religiosity as potentially protective in some settings and potentially harmful in others. Applicants are encouraged to examine both positive and negative effects rather than assuming religiosity is automatically beneficial or automatically risky.

What does NIH mean by focusing on mechanisms, mediators, and moderators?

NIH is looking for studies that go beyond simple correlations between religiosity and risk behaviors. Projects are expected to investigate (1) mechanisms: how religiosity exerts influence, (2) mediators: factors that help explain the relationship, and (3) moderators: conditions under which the relationship changes across groups or contexts.

What are examples of mediators that applicants might examine?

The FOA provides examples such as peer norms, parental monitoring, moral beliefs, stigma, social support, and mental health as possible mediators that could explain links between religiosity/spirituality and HIV-related risk behaviors.

What are examples of moderators that applicants might examine?

The FOA highlights moderators such as age, gender, sexual orientation, race and ethnicity, socioeconomic status, family structure, denomination or tradition, level of community religious involvement, and local cultural context.

How important is intergenerational transmission in this FOA?

Intergenerational transmission is specifically highlighted. Strong applications would typically consider how beliefs and practices are communicated from parents or caregivers to children, how youth interpret and adopt those messages, and how family and community religious life intersects with adolescent development.

How does the FOA address religious diversity?

The FOA stresses the increasingly pluralistic religious landscape in the United States and invites research attentive to diverse religions and belief systems. This implies interest in culturally grounded, context-sensitive designs that can reflect differences in norms, teachings, and community practices across traditions and settings.

Does the FOA encourage measuring religiosity in multiple ways?

Yes. The FOA indicates interest in distinguishing dimensions of religiosity and spirituality rather than treating religiosity as a single uniform factor. Examples include affiliation, attendance, private practices, personal salience, spirituality, doctrinal beliefs, and participation in youth programs.

What grant mechanism is used and what type of projects fit it?

This FOA uses the NIH R01 mechanism, intended for full-scale, hypothesis-driven research projects that support substantial, multi-year work.

Are there companion funding opportunities with the same scientific scope?

Yes. The FOA notes companion announcements of identical scientific scope using other NIH mechanisms: an R03 small research grant and an R21 exploratory/developmental grant.

Are the budget and project period fixed?

No. Budgets and project periods are not set to a single fixed amount because NIH expects proposals to vary in size and complexity. The number of awards and total dollars depend on the number of applications received, their scientific merit, and requested costs and duration.

Who is eligible to apply?

Eligibility is broad. The FOA includes public and private institutions of higher education; nonprofits with or without 501(c)(3) status; small businesses and other for-profit organizations (other than small businesses); state governments; U.S. territories or possessions; and tribal entities including federally recognized tribes, other tribal governments, and tribally designated organizations.

Are specific institution types explicitly welcomed?

Yes. The FOA explicitly lists and welcomes participation from organizations such as Hispanic-serving institutions, HBCUs, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, regional organizations, and eligible federal agencies.

Can faith-based and community-based organizations apply?

Yes. The FOA states that faith-based and community-based organizations may apply.

Are foreign (non-U.S.) entities eligible?

Yes. The FOA indicates that foreign (non-U.S.) entities are eligible, suggesting openness to international perspectives or comparative work as long as the research fits the FOA focus.

Is cost sharing or matching required?

No. The FOA does not require cost sharing or matching.

What federal program areas and CFDA numbers are associated with this opportunity?

The listing associates the opportunity with activity areas spanning education, health, income security, and social services. It includes CFDA program numbers for alcohol research, nursing research, and child health and human development extramural research: 93.273, 93.361, and 93.865.

When was the FOA posted and what is its current status?

The opportunity was posted on December 15, 2006. It used multiple receipt dates rather than a single deadline, and it was archived on August 5, 2009.

Where were applicants directed for the full announcement details?

Applicants were directed to the complete announcement page on grants.nih.gov for full details.

Who was listed as a contact for access or linking issues?

The source listing provided an NIH Office of Extramural Research webmaster contact for access or linking issues related to the announcement page.

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