School based Interventions to Prevent Obesity (R01) | Apply Online

Opportunity Summary:

The NIH funding opportunity "School based Interventions to Prevent Obesity (R01)" (Funding Opportunity Number PA 07-180) supports rigorous, controlled research that tests school-based strategies aimed at reducing childhood obesity. The central idea is to get academic researchers and school systems working together as true partners to design, implement, and evaluate interventions that can be delivered in real-world school settings. Beyond simply testing whether a single program works, the announcement explicitly encourages studies that compare different approaches head-to-head and that use research methods capable of identifying whether combinations of approaches produce added benefits (synergy), such as when nutrition changes and physical activity supports reinforce each other more than either would alone.

This FOA uses the NIH Research Project Grant (R01) mechanism, which is typically intended for larger, more comprehensive projects with stronger evidence, clearer hypotheses, and more robust study designs than smaller pilot mechanisms. The announcement notes that it is aligned in scientific scope with companion opportunities that use the R03 (small grant) and R21 (exploratory/developmental) mechanisms, meaning applicants should choose the mechanism that best matches the maturity and scale of their proposed work. In practical terms, PA 07-180 is for teams ready to run a well-controlled, school-based trial or other strong evaluative design rather than an early-stage feasibility effort.

Funding levels and the number of awards are not fixed in advance. NIH indicates that budgets and project periods may vary substantially because school-based intervention research can range from single-district studies to multi-site trials, and can differ in intensity, duration, and measurement requirements. Awards will ultimately depend on the number of applications received, their scientific quality, proposed duration, and requested costs, as well as NIH program priorities and available funds. There is no cost sharing or matching requirement stated for this opportunity.

Eligibility is broad and includes many types of institutions and organizations that can credibly carry out school-based health research. Eligible applicants include public and private institutions of higher education, nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education in that category), small businesses and other for-profit organizations (with the exception that "other than small business" for-profits are also listed as eligible), and multiple levels of government entities (state, county, city/township, special district). School districts are included (notably independent school districts), as are public housing authorities/Indian housing authorities. Tribal entities are eligible, including federally recognized tribal governments, other tribal governments, and tribally designated organizations. The FOA also highlights eligibility for minority-serving and mission-driven institutions and organizations, including Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian-serving institutions. Importantly, foreign (non-U.S.) institutions may apply, and eligible federal agencies may also apply. Faith-based and community-based organizations are explicitly included as eligible applicants, which reflects NIH's interest in reaching diverse communities and building interventions that can work across different school and community contexts.

The program sits at the intersection of education and public health, reflecting NIH's interest in obesity prevention as a multi-factor problem influenced by school environments, policies, curricula, and social conditions. The listing includes multiple CFDA numbers associated with different NIH research areas, including minority health and health disparities, nursing research, cancer prevention, cardiovascular research, and child health and human development. That mix signals that NIH expects applications to address obesity prevention with strong biomedical and behavioral relevance, and also that proposals may be particularly compelling when they consider equity, disparities, and downstream health outcomes associated with obesity.

In terms of timing, the opportunity was posted December 15, 2006, and it used multiple receipt dates rather than a single deadline, meaning applications were accepted on recurring NIH due dates during the active period of the announcement. The archive date is August 5, 2009, which indicates the specific announcement is no longer active as written, but it remains useful as a reference point for what NIH has historically sought in school-based obesity prevention trials. The full announcement was available through the NIH Grants Guide (link provided in the source text), and NIH listed the NIH Office of Extramural Research (OER) webmaster contacts for access or technical issues.

Overall, PA 07-180 is designed for well-planned, school-embedded intervention research that goes beyond basic program delivery and instead produces defensible evidence about what works, what works best compared to alternatives, and whether layered interventions can interact to produce stronger results than single-component efforts. The emphasis on formal partnerships with school systems and on controlled evaluations underscores NIH's expectation that studies be both scientifically rigorous and operationally realistic in the school setting.

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