Opportunity Information: Apply for PA 06 335
Apply for PA 06 335
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Tools to Mitigate and Understand the Mental Health Effects of National Disasters SBIR R43/R44" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
- This funding opportunity was created on Jan 26, 2009 and posted on Apr 7, 2006.
- Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses Others (see text field entitled Additional Information on Eligibility for clarification).
- Foreign institutions are not eligible to apply. Only United States small business concerns (SBCs) are eligible to submit SBIR applications. A small business concern is one that, at the time of award for both Phase I and Phase II awards, meets all of the following criteria Is independently owned and operated, is not dominant in the field of operation in which it is proposing, has a place of business in the United States and operates primarily within the United States or makes a significant contribution to the US economy, and is organized for profit. Is (a) at least 51 owned and controlled by one or more individuals who are citizens of, or permanent resident aliens in, the United States, or (b) for SBIR only, it must be a for profit business concern that is at least 51 owned and controlled by another for profit business concern that is at least 51 owned and controlled by one or more individuals who are citizens of, or permanent resident aliens in, the United States. Has, including its affiliates, an average number of employees for the preceding 12 months not exceeding 500, and meets the other regulatory requirements found in 13 C.F.R. Part 121. Business concerns are generally considered to be affiliates of one another when either directly or indirectly, (a) one concern controls or has the power to control the other or (b) a third party/parties controls or has the power to control both.
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Opportunity Summary:
The NIH funding opportunity PA 06 335, titled "Tools to Mitigate and Understand the Mental Health Effects of National Disasters" (SBIR R43/R44), supports small businesses that want to research and develop practical, commercializable products focused on the mental health impacts that can follow major national disasters. The central goal is to encourage innovations that either help reduce or manage disaster-related mental health problems, or improve how those problems are studied and understood. The announcement uses disasters such as Hurricanes Katrina and Rita as examples, and it is explicitly concerned with both direct victims and the people who responded to their needs, recognizing that responders can face serious psychological strain as well.
The types of projects NIH is looking for span two broad categories. First are tools meant to mitigate harm, which can include assessment tools, prevention approaches, treatment interventions, and methods for communicating helpful information to affected communities. These could be used in clinical settings, community-based programs, schools, shelters, or other environments where people seek support after a disaster. Second are tools meant to improve understanding, such as research instruments or platforms that help measure, track, or analyze mental health outcomes in disaster contexts. In both cases, the products should be designed with a clear path toward real-world use and commercialization, which is a core requirement of the SBIR program.
A key expectation is that the proposed tools reflect the cultural context of the populations they are intended to serve. The FOA emphasizes that cultural considerations are not optional details but central to whether a tool will be valid, effective, and broadly usable. In practice, this means applicants should show how language, norms, values, local experiences, and community realities are incorporated into tool design and evaluation, especially because disaster-affected communities can be diverse and may have different barriers to care, trust, and access to mental health resources.
The program is structured around the SBIR grant mechanisms R43/R44, meaning applicants can propose Phase I, Phase II, or a Fast Track application that combines both phases. Phase I is meant to establish feasibility and early proof of concept, and the FOA allows up to 250,000 dollars in total costs per year for up to two years. Phase II supports more advanced research and development, including further testing, refinement, and steps toward commercialization, with budgets up to 450,000 dollars in total costs per year for up to three years. The FOA notes that there is no set-aside pot of money reserved specifically for this announcement; awards depend on the number and quality of applications received and overall funding availability.
Eligibility is limited to U.S. small business concerns, and foreign institutions are not allowed to apply. To qualify as an SBC, the organization must be for-profit, independently owned and operated, not dominant in its field, and have a place of business in the United States while operating primarily in the U.S. or making a significant contribution to the U.S. economy. Ownership rules generally require at least 51 percent ownership and control by U.S. citizens or permanent residents (with an additional SBIR-allowed structure where a qualifying for-profit company may be majority-owned by another qualifying for-profit company). The small business size standard also applies: including affiliates, the company must have averaged no more than 500 employees over the preceding 12 months and meet related SBA affiliation rules under 13 C.F.R. Part 121.
On the personnel side, the FOA invites any individual with the appropriate expertise to participate, and it reiterates NIH's encouragement for applicants from underrepresented racial and ethnic groups and individuals with disabilities. For SBIR applications specifically, the Project Director/Principal Investigator must be primarily employed by the small business (more than 50 percent) at the time of award and for the duration of the project. The FOA also allows a company to submit multiple applications as long as each one is scientifically distinct, which can matter for businesses developing different tools or addressing different aspects of disaster-related mental health needs.
Administratively, this opportunity is classified as a discretionary grant in the health area and is associated with CFDA 93.242 (Mental Health Research Grants). It has multiple receipt dates rather than a single deadline, and it was posted April 7, 2006, with the archive date listed as June 1, 2009. The FOA runs in parallel with a companion announcement of identical scientific scope for the STTR program (PA 06 336, using R41/R42 mechanisms), which is relevant for small businesses that plan a more formal collaborative R&D effort with a nonprofit research institution. For further details and the full text, NIH provides the full announcement link at http://grants.nih.gov/grants/guide/pa-files/PA-06-335.html and directs technical access issues to the NIH Office of Extramural Research webmaster.
Frequently Asked Questions (FAQ)
What is NIH Funding Opportunity PA-06-335?
PA-06-335 is an NIH SBIR funding opportunity titled "Tools to Mitigate and Understand the Mental Health Effects of National Disasters." It supports U.S. small businesses that want to research and develop practical, commercializable products focused on mental health impacts that can follow major national disasters.
What is the main goal of this SBIR opportunity?
The central goal is to encourage innovations that either (1) help reduce or manage disaster-related mental health problems or (2) improve how those problems are studied and understood, with a clear path toward real-world use and commercialization.
What kinds of disasters does the announcement focus on?
The FOA uses major national disasters as the context for the work and provides Hurricanes Katrina and Rita as examples.
Who are the intended beneficiaries of the tools developed under this FOA?
The FOA is concerned with both direct victims of disasters and people who respond to their needs (responders). It explicitly recognizes that responders can face serious psychological strain as well.
What are the two broad project categories NIH is looking for?
The FOA describes two broad categories: (1) tools intended to mitigate harm and (2) tools intended to improve understanding of disaster-related mental health outcomes.
What are examples of "tools meant to mitigate harm" under this opportunity?
Mitigation-focused tools can include assessment tools, prevention approaches, treatment interventions, and methods for communicating helpful information to disaster-affected communities.
Where might mitigation tools be used after a disaster?
The FOA notes that these tools could be used in clinical settings, community-based programs, schools, shelters, or other environments where people seek support after a disaster.
What are examples of "tools meant to improve understanding" under this opportunity?
Understanding-focused tools can include research instruments or platforms that help measure, track, or analyze mental health outcomes in disaster contexts.
Does this FOA require a commercialization plan or commercial potential?
Yes. A core requirement of the SBIR program, as reflected in the FOA, is that proposed products should be designed with a clear path toward real-world use and commercialization.
How important are cultural considerations in proposed tools?
Cultural considerations are emphasized as central, not optional. The FOA expects tools to reflect the cultural context of the populations they are intended to serve, because culture can affect validity, effectiveness, usability, trust, access, and barriers to care.
What types of cultural factors does the FOA expect applicants to address?
The FOA highlights factors such as language, norms, values, local experiences, and community realities, especially since disaster-affected communities can be diverse.
What SBIR mechanisms are used in PA-06-335?
This opportunity uses the SBIR grant mechanisms R43/R44. Applicants may propose a Phase I application, a Phase II application, or a Fast Track application that combines both phases.
What is the purpose of SBIR Phase I in this program?
Phase I is intended to establish feasibility and provide early proof of concept for the proposed tool or product.
What is the maximum budget and project period for Phase I?
The FOA allows up to $250,000 in total costs per year for up to two years for Phase I.
What is the purpose of SBIR Phase II in this program?
Phase II supports more advanced research and development, including further testing, refinement, and steps toward commercialization.
What is the maximum budget and project period for Phase II?
The FOA allows up to $450,000 in total costs per year for up to three years for Phase II.
Is there dedicated funding set aside specifically for PA-06-335 awards?
No. The FOA notes there is no set-aside pot of money reserved specifically for this announcement. Awards depend on the number and quality of applications received and overall funding availability.
Who is eligible to apply?
Eligibility is limited to U.S. small business concerns (SBCs). Foreign institutions are not allowed to apply.
What qualifies an organization as a U.S. small business concern for this FOA?
To qualify as an SBC, the organization must be for-profit, independently owned and operated, not dominant in its field, have a place of business in the United States, and operate primarily in the U.S. or make a significant contribution to the U.S. economy.
What are the ownership and control requirements for SBIR eligibility described in the FOA?
Ownership rules generally require at least 51% ownership and control by U.S. citizens or permanent residents. The FOA also notes an SBIR-allowed structure where a qualifying for-profit company may be majority-owned by another qualifying for-profit company.
What is the employee size standard for the small business?
Including affiliates, the company must have averaged no more than 500 employees over the preceding 12 months and meet related SBA affiliation rules under 13 C.F.R. Part 121.
Who can serve as Project Director/Principal Investigator (PD/PI) on an SBIR application?
Any individual with the appropriate expertise may participate, but for SBIR applications the PD/PI must be primarily employed by the small business (more than 50%) at the time of award and for the duration of the project.
Does NIH encourage participation from underrepresented groups?
Yes. The FOA reiterates NIH encouragement for applicants from underrepresented racial and ethnic groups and individuals with disabilities.
Can a small business submit more than one application to this FOA?
Yes. The FOA allows a company to submit multiple applications as long as each application is scientifically distinct.
What is the CFDA number associated with this opportunity?
The FOA is associated with CFDA 93.242 (Mental Health Research Grants).
How is this opportunity classified administratively?
The opportunity is classified as a discretionary grant in the health area.
Is there a single deadline for submission?
No. The FOA states it has multiple receipt dates rather than a single deadline.
When was PA-06-335 posted, and when was it archived?
The FOA was posted on April 7, 2006, and the archive date is listed as June 1, 2009.
Is there a related STTR opportunity with the same scientific scope?
Yes. The FOA runs in parallel with a companion announcement of identical scientific scope for the STTR program: PA-06-336, which uses the R41/R42 mechanisms.
When might the STTR companion announcement be relevant instead of SBIR?
The companion STTR announcement may be relevant for small businesses that plan a more formal collaborative R&D effort with a nonprofit research institution.
Where can applicants find the full NIH announcement text?
The FOA provides the full announcement link here: http://grants.nih.gov/grants/guide/pa-files/PA-06-335.html
Who should be contacted for technical access issues with the FOA materials?
The FOA directs technical access issues to the NIH Office of Extramural Research webmaster.
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Previous opportunity: NIDA Phase II Small Business Innovation Research (SBIR R44) Competing Renewal Awards
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 06 335) also looked into and applied for these:
| Funding Opportunity |
|---|
| Tools to Mitigate and Understand the Mental Health Effects of National Disasters STTR R41/R42 Apply for PA 06 336 Funding Number: PA 06 336 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Novel Tools for Investigating Brain derived GPCRs in Mental Health Research (STTR R41/R42) Apply for PA 06 374 Funding Number: PA 06 374 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Novel Tools for Investigating Brain derived GPCRs in Mental Health Research (SBIR R43/R44) Apply for PA 06 375 Funding Number: PA 06 375 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Longitudinal Surveys of the Elderly SBIR Initiative (R43/R44) Apply for PA 06 465 Funding Number: PA 06 465 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Longitudinal Surveys of the Elderly STTR Initiative (R41/R42) Apply for PA 06 464 Funding Number: PA 06 464 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Technological Enhancements for Surveys of the Elderly STTR (R41/R42) Initiative Apply for PA 06 472 Funding Number: PA 06 472 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Technological Enhancements for Surveys of the Elderly SBIR (R43/R44) Initiative Apply for PA 06 471 Funding Number: PA 06 471 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| New Technology to Screen for Mild Hearing Loss in Children (SBIR R43/R44) Apply for PA 06 546 Funding Number: PA 06 546 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| New Technology to Screen for Mild Hearing Loss in Children (STTR R41/R42) Apply for PA 06 547 Funding Number: PA 06 547 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| New Approaches to Arrhythmia Detection and Treatment (STTR R41/R42) Apply for PA 07 031 Funding Number: PA 07 031 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| New Approaches to Arrhythmia Detection and Treatment (SBIR R43/R44) Apply for PA 07 032 Funding Number: PA 07 032 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Collaborative R01s for Clinical and Services Studies of Mental Disorders, AIDS and Alcohol Use Disorders (R01) Apply for PA 07 092 Funding Number: PA 07 092 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Advanced Tools and Technologies for Deep Brain Stimulation in Movement Disorders STTR (R41/R42) Apply for PA 07 395 Funding Number: PA 07 395 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Computational Tools for Research in Neuroscience, Behavioral Science and Mental Health STTR R41/R42 Apply for PA 07 423 Funding Number: PA 07 423 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Computational Tools for Research in Neuroscience, Behavioral Science and Mental Health SBIR R43/R44 Apply for PA 07 424 Funding Number: PA 07 424 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| New Technology for Proteomics and Glycomics (SBIR R43/R44) Apply for PA 07 451 Funding Number: PA 07 451 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| New Technology for Proteomics and Glycomics (STTR R41/R42) Apply for PA 07 452 Funding Number: PA 07 452 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| High Throughput Tools for Brain and Behavior (SBIR R43/R44) Apply for PA 08 001 Funding Number: PA 08 001 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| High Throughput Tools for Brain and Behavior (STTR R41/R42) Apply for PA 08 002 Funding Number: PA 08 002 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Development of PET and SPECT Ligands for Brain Imaging (SBIR R43/R44) Apply for PA 08 137 Funding Number: PA 08 137 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
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