Opportunity Information: Apply for PAR 09 185

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Translational Programs in Lung Diseases (P01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.838 Lung Diseases Research.
  • This funding opportunity was created on May 14, 2009 and posted on May 13, 2009.
  • Applicants must submit their applications by Sep 25, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: County governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Native American tribal governments (Federally recognized) City or township governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The Translational Programs in Lung Diseases (P01) opportunity (Funding Opportunity Number PAR 09-185) is a National Institutes of Health program led by the National Heart, Lung, and Blood Institute (NHLBI) that supports collaborative, team-based translational research aimed at improving real-world clinical care for lung diseases and sleep disorders. The central idea is to move discoveries from mechanistic or basic research into clinical applications that can strengthen prevention strategies, sharpen diagnostic approaches, and produce better treatments. In practice, this means applicants are expected to connect laboratory or mechanistic insights to patient-centered or clinically relevant outcomes, building a coherent research program that accelerates translation from bench to bedside (and, where appropriate, back again through iterative learning).

The funding mechanism is a Program Project Grant (P01), which is designed for multi-component research programs that require close coordination across several interrelated projects rather than a single standalone study. Under this FOA, an application must include at least three distinct research projects plus at least two shared resource cores, with an administrative core typically serving as one of the required cores. The projects should be scientifically linked by a unifying theme and structured so that the combined program is stronger and more impactful than the individual components would be on their own. The cores are meant to provide centralized support that multiple projects can use, helping to increase efficiency, promote standardization, and enable deeper collaboration across the program.

Award size, project period, and the number of awards were not fixed in advance, reflecting how widely translational lung and sleep research programs can differ in scope and cost. Instead, NHLBI anticipated that budgets and durations would vary across applicants, and that final funding decisions would depend on the overall pool of submissions, including the number of applications received, their scientific quality, the proposed timelines, and the requested costs. The opportunity is categorized as discretionary grant funding in the health area and is associated with CFDA 93.838 (Lung Diseases Research). There is no cost sharing or matching requirement stated for this program.

Eligibility is broad and includes many types of U.S.-based organizations and governmental entities. Eligible applicants include public and private institutions of higher education, nonprofits (including those with and without 501(c)(3) status, as applicable), for-profit organizations (other than small businesses), small businesses, and a wide range of government bodies such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities (including Indian housing authorities). The eligibility list also explicitly encompasses organizations that serve specific communities or have specific designations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and certain tribal organizations and regional organizations. Faith-based and community-based organizations are also included, and eligible agencies of the federal government and U.S. territories or possessions are referenced as allowable applicants in the eligibility information.

Key dates show the FOA was posted in mid-May 2009, with an original and final closing date listed as September 25, 2012, and an archive date of October 26, 2012. That combination indicates the opportunity is no longer active, but the archived announcement remains useful as a reference for understanding NHLBI priorities and the P01 structure used for translational lung and sleep disorder programs. For full historical details, the announcement link points to the NIH Grants Guide page associated with PAR 09-185, and the NIH Office of Extramural Research webmaster contact is provided for access or technical issues with the posting.

FAQs: Translational Programs in Lung Diseases (P01) - PAR 09-185

What is the Translational Programs in Lung Diseases (P01) opportunity (PAR 09-185)?

PAR 09-185 is a National Institutes of Health (NIH) funding opportunity led by the National Heart, Lung, and Blood Institute (NHLBI). It supports collaborative, team-based translational research programs focused on improving real-world clinical care for lung diseases and sleep disorders.

What is the main goal of this program?

The central goal is to move discoveries from mechanistic or basic research into clinical applications that strengthen prevention strategies, sharpen diagnostic approaches, and produce better treatments. The program emphasizes connecting laboratory insights to patient-centered or clinically relevant outcomes, with an expectation of accelerating translation from bench to bedside (and, where appropriate, back again through iterative learning).

What funding mechanism does this opportunity use?

This opportunity uses the Program Project Grant (P01) mechanism, which is designed for multi-component research programs requiring close coordination across several interrelated projects rather than a single standalone study.

What kind of research approach is expected under this FOA?

Applicants are expected to propose a coherent translational research program that links mechanistic or laboratory discoveries to clinically relevant questions and outcomes. The intent is practical impact on clinical care for lung diseases and sleep disorders through prevention, diagnosis, and treatment advances.

How many research projects are required in a P01 application under PAR 09-185?

An application must include at least three distinct research projects.

How many cores are required, and what is typically included?

An application must include at least two shared resource cores. An administrative core is typically included and generally serves as one of the required cores.

What is the purpose of cores in this P01 structure?

Cores provide centralized support resources that multiple projects can use. Their role is to increase efficiency, promote standardization, and enable deeper collaboration across the overall program.

Do the projects need to be connected to each other?

Yes. The projects are expected to be scientifically linked by a unifying theme and structured so the combined program is stronger and more impactful than the individual components would be on their own.

Is this opportunity limited to lung diseases only, or does it include sleep disorders too?

It includes both lung diseases and sleep disorders, with an emphasis on translational research that improves real-world clinical care.

Were award size, project period, and number of awards fixed?

No. Award size, project period, and the number of awards were not fixed in advance. NHLBI anticipated that budgets and durations would vary depending on the scope and cost of proposed programs.

What factors influenced final funding decisions?

Final decisions were expected to depend on the overall pool of submissions, including the number of applications received, their scientific quality, the proposed timelines, and the requested costs.

What type of funding is this categorized as?

The opportunity is categorized as discretionary grant funding in the health area.

What CFDA number is associated with this opportunity?

This opportunity is associated with CFDA 93.838 (Lung Diseases Research).

Is cost sharing or matching required?

No cost sharing or matching requirement is stated for this program.

Who is eligible to apply?

Eligibility is broad and includes many U.S.-based organizations and governmental entities. Eligible applicants include public and private institutions of higher education; nonprofits (including those with and without 501(c)(3) status, as applicable); for-profit organizations (other than small businesses); small businesses; and a wide range of government bodies such as state, county, and city or township governments, special district governments, independent school districts, and public housing authorities (including Indian housing authorities).

Are organizations with specific designations explicitly included (for example, HBCUs or tribal colleges)?

Yes. The eligibility list explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and certain tribal organizations and regional organizations.

Are faith-based and community-based organizations eligible?

Yes. Faith-based and community-based organizations are included in the eligibility information.

Are government agencies and U.S. territories referenced as eligible applicants?

Yes. Eligible agencies of the federal government and U.S. territories or possessions are referenced as allowable applicants in the eligibility information.

When was this FOA posted, and what were the closing dates?

The FOA was posted in mid-May 2009. The original and final closing date listed is September 25, 2012, and the archive date is October 26, 2012.

Is PAR 09-185 currently active?

No. Because the closing date and archive date are in 2012, the opportunity is no longer active. The archived announcement remains useful as a historical reference for NHLBI priorities and the P01 structure described.

Where can someone find the official historical announcement information?

The announcement link points to the NIH Grants Guide page associated with PAR 09-185 for full historical details.

Who is listed as a contact for access or technical issues with the posting?

The NIH Office of Extramural Research webmaster contact is provided for access or technical issues related to the posting.

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