Understanding and Treating Co Morbid Conditions in Adolescents with Intellectual and Developmental Disabilities (R21) | Apply Online

Opportunity Summary:

The grant opportunity titled "Understanding and Treating Co-Morbid Conditions in Adolescents with Intellectual and Developmental Disabilities (R21)" (Funding Opportunity Number PA-11-041) was a discretionary National Institutes of Health (NIH) funding announcement administered through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). It invited investigator-initiated research focused on adolescence as a critical developmental period for individuals with intellectual and developmental disabilities (IDD), with an emphasis on understanding the factors that shape day-to-day functioning and overall quality of life. The framing of the opportunity highlights that adolescence can bring new or intensified health, behavioral, mental health, and social challenges for youth with IDD, and that these co-occurring (co-morbid) conditions can compound disability-related needs and affect outcomes at home, in school, in healthcare settings, and in the community.

Although the title specifies the R21 mechanism, the announcement broadly encouraged research project grant applications across several NIH mechanisms (R01, R03, and R21). For the R21 in particular, the intent typically aligns with exploratory or developmental research that can test novel ideas, pilot interventions, generate preliminary data, or open up new lines of inquiry that may later be scaled into larger studies. Within the scope of this FOA, that exploratory focus would apply to studying co-morbid conditions in adolescents with IDD and to developing or testing strategies that could improve functioning, participation, and well-being. The content emphasis was not limited to treatment alone; it also encompassed identifying and analyzing the underlying factors that influence adolescent outcomes, which can include biological, psychological, social, environmental, educational, and healthcare-related contributors.

In practical terms, projects responsive to this opportunity would be expected to center on adolescents with IDD and examine how co-occurring conditions affect their trajectories and quality of life. "Co-morbid conditions" in this context can be interpreted broadly to include mental and behavioral health conditions, medical issues, or other secondary challenges that frequently occur alongside IDD and that may interfere with learning, independence, family functioning, peer relationships, and transition planning. Research might address questions such as how these conditions are identified in adolescents with IDD, how they interact with developmental changes during puberty and teenage years, what barriers exist to effective care, and which interventions, supports, or service models are most promising for improving outcomes. The overarching goal is to produce knowledge that helps adolescents with IDD function better and experience a higher quality of life during a period of rapid change and increasing expectations for autonomy.

Administratively, this was a grant funding instrument in the Health, Income Security, and Social Services activity category, listed under CFDA 93.865 (Child Health and Human Development Extramural Research). The announcement specified no cost sharing or matching requirement, meaning applicants were not required to contribute non-federal funds as a condition of receiving an award. For the R21 mechanism, the award ceiling was listed as $200,000, signaling the maximum level of support anticipated under that specific grant type within this FOA. The opportunity was posted on November 17, 2010, and remained open through the original and final closing date of January 7, 2014, with an archive date of February 7, 2014, indicating it is no longer active for new submissions under that specific announcement.

Eligibility was broad and inclusive, reflecting NIH's general approach to welcoming proposals from many institutional types capable of conducting health-related research. Eligible applicants included public and private institutions of higher education, nonprofits with and without 501(c)(3) status, small businesses and other for-profit organizations (beyond small businesses), state and local governmental entities (including counties, cities or townships, special district governments, and independent school districts), and housing authorities including public or Indian housing authorities. The FOA also explicitly included tribal governments and tribal organizations, and it extended eligibility to a wide array of mission-serving institutions and organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, and Tribally Controlled Colleges and Universities (TCCUs). Faith-based and community-based organizations were also eligible, along with regional organizations, U.S. territories or possessions, and even non-U.S. entities (foreign organizations), as well as eligible federal agencies, reflecting the NIH's capacity to fund scientifically meritorious research across diverse settings and populations.

For applicants seeking the full requirements, the official details were hosted in the NIH Grants Guide entry linked in the announcement (http://grants.nih.gov/grants/guide/pa-files/PA-11-041.html). The contact information provided was primarily for technical assistance accessing the announcement online or resolving linking issues, directing users to the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

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Next opportunity: Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) Study to Explore Early Development (SEED) II (U01)

Previous opportunity: Understanding and Treating Co Morbid Conditions in Adolescents with Intellectual and Developmental Disabilities (R03)

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