Opportunity Information: Apply for PAR 10 191
Apply for PAR 10 191
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Vulvodynia Systematic Epidemiologic, Etiologic or Therapeutic Studies (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on May 7, 2010 and posted on May 7, 2010.
- Applicants must submit their applications by Sep 21, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: For profit organizations other than small businesses Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Special district governments City or township governments County governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized).
- Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Vulvodynia - Systematic Epidemiologic, Etiologic or Therapeutic Studies (R03) funding opportunity (PAR-10-191) is a National Institutes of Health (NIH) discretionary grant program designed to stimulate new, investigator-initiated research focused on vulvodynia and closely related symptom-based conditions. Vulvodynia is described in the announcement as a chronic pelvic pain condition affecting women, and the central intent of the FOA is to grow the scientific evidence base needed to improve how the condition is identified, prevented, and treated. Projects can be positioned anywhere along the research spectrum, including basic science, clinical studies, translational research, epidemiology, and behavioral research, as long as the work is clearly tied to understanding vulvodynia and moving the field toward better diagnostic and therapeutic approaches.
A major theme of the FOA is building foundational knowledge that can enable future prevention and treatment strategies. The announcement highlights several areas where progress is especially needed: clarifying vulvodynia pathophysiology, identifying biological and behavioral risk factors, describing the condition's natural history (how it begins, changes, and persists over time), and exploring genetic contributions. In practical terms, NIH is signaling interest in studies that can help explain why vulvodynia develops in some people and not others, what factors worsen or protect against symptoms, and what mechanisms might be targeted for improved interventions. Because the FOA also references "related symptom-based conditions," it leaves room for studies that examine overlap with other chronic pain or pelvic pain presentations when that overlap helps illuminate vulvodynia specifically.
This opportunity uses the NIH Small Research Grant (R03) mechanism, which is intended for smaller, tightly scoped projects that can be completed relatively quickly and with limited resources. R03 awards are commonly used for pilot studies, discrete data-collection efforts, secondary analyses, feasibility testing, preliminary mechanistic work, or early-stage evaluation of clinical or behavioral approaches that are not yet ready for a large-scale trial. The FOA explicitly notes that it runs in parallel with two companion announcements that share the same scientific scope but support different grant sizes and stages of development: PAR-10-192 under the R21 Exploratory/Developmental mechanism and PAR-10-190 under the R01 Research Project Grant mechanism. In other words, the scientific topics are aligned across the three announcements, but applicants choose the mechanism that best fits the maturity, scale, and resource needs of their proposed study.
Funding levels and the number of awards are not fixed in the announcement. NIH indicates that award size and duration will vary based on the nature and scope of the proposed projects, and that the total amount awarded and the number of funded applications will depend on factors like the mix of mechanisms, overall application quality, the proposed project periods, and the requested budgets. The program is listed under CFDA 93.865 (Child Health and Human Development Extramural Research), reflecting the NIH institute alignment for the opportunity, and the announcement specifies that cost sharing or matching is not required.
Eligibility is broad and includes a wide range of organization types, which makes the program accessible to many research and community-oriented entities. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) nonprofits), for-profit organizations other than small businesses, small businesses, and multiple levels of government (state, county, city or township, and special district governments). Tribal eligibility is also expansive, including federally recognized tribal governments as well as other tribal organizations, and tribally controlled colleges and universities (TCCUs). The eligibility language also calls out Alaska Native and Native Hawaiian Serving Institutions, Historically Black Colleges and Universities (HBCUs), and Hispanic-serving institutions, as well as faith-based or community-based organizations. Notably, the FOA indicates that non-U.S. (foreign) entities and regional organizations may be eligible, and that U.S. territories or possessions are included, which can be important for building multinational or cross-jurisdiction collaborations where appropriate.
Key administrative details in the source data show that the FOA was posted and created on May 7, 2010, with an original and current closing date of September 21, 2012, and an archive date of October 21, 2012. That means the announcement is no longer active as written, but it remains useful as a record of NIH priorities and as a template for the kinds of vulvodynia-focused projects NIH has sought to fund under small-grant mechanisms. The full announcement was hosted on the NIH grants policy/guide site, and NIH provided standard support contacts for access or technical issues, including GrantsInfo (phone 301-435-0714) and the NIH Office of Extramural Research webmaster for linking problems.
FAQs: Vulvodynia - Systematic Epidemiologic, Etiologic or Therapeutic Studies (R03) (PAR-10-191)
What is PAR-10-191?
PAR-10-191 is an NIH discretionary funding opportunity announcement (FOA) that uses the Small Research Grant (R03) mechanism to support investigator-initiated research focused on vulvodynia and closely related symptom-based conditions.
What is the main goal of this funding opportunity?
The central goal is to stimulate new research that expands the scientific evidence base for vulvodynia so the field can move toward better identification, prevention, and treatment of the condition.
How does the FOA describe vulvodynia?
The announcement describes vulvodynia as a chronic pelvic pain condition affecting women.
What kinds of research does the FOA support?
Projects can fall anywhere along the research spectrum, including basic science, clinical studies, translational research, epidemiology, and behavioral research, as long as the work is clearly tied to understanding vulvodynia and advancing diagnostic and therapeutic approaches.
What scientific topics are emphasized as priorities?
The FOA highlights the need for progress in clarifying vulvodynia pathophysiology, identifying biological and behavioral risk factors, describing natural history (how the condition begins, changes, and persists over time), and exploring genetic contributions.
Does this FOA allow studies on conditions related to vulvodynia?
Yes. The FOA references "related symptom-based conditions" and allows studies that examine overlap with other chronic pain or pelvic pain presentations when that overlap helps illuminate vulvodynia specifically.
What is the R03 mechanism and what is it typically used for?
The R03 (Small Research Grant) mechanism is intended for smaller, tightly scoped projects that can be completed relatively quickly with limited resources. It is commonly used for pilot studies, discrete data-collection efforts, secondary analyses, feasibility testing, preliminary mechanistic work, or early-stage evaluation of clinical or behavioral approaches that are not yet ready for a large-scale trial.
Are there companion NIH opportunities with the same scientific scope?
Yes. The FOA runs in parallel with two companion announcements that share the same scientific scope but support different grant sizes and stages: PAR-10-192 (R21 Exploratory/Developmental) and PAR-10-190 (R01 Research Project Grant).
How should an applicant choose between R03, R21, and R01 for this topic area?
The scientific topics are aligned across the three announcements, but applicants choose the mechanism that best fits the maturity, scale, and resource needs of the proposed study (smaller, tightly scoped work for R03 versus larger or more developed projects under R21 or R01).
Is the funding amount or number of awards specified?
No. Funding levels and the number of awards are not fixed. NIH indicates that award size and duration vary based on project nature and scope, and the total amount and number of awards depend on factors such as application quality, the mix of mechanisms, project periods, and requested budgets.
Is cost sharing or matching required?
No. The FOA specifies that cost sharing or matching is not required.
What CFDA program is associated with this opportunity?
The opportunity is listed under CFDA 93.865, identified as Child Health and Human Development Extramural Research.
What types of organizations are eligible to apply?
Eligibility is broad and includes public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (501(c)(3) and non-501(c)(3)), for-profit organizations other than small businesses, small businesses, and multiple levels of government (state, county, city or township, and special district governments).
Are tribal entities and tribally controlled institutions eligible?
Yes. Eligibility includes federally recognized tribal governments, other tribal organizations, and tribally controlled colleges and universities (TCCUs).
Are minority-serving institutions explicitly included in the eligibility language?
Yes. The eligibility language calls out Alaska Native and Native Hawaiian Serving Institutions, Historically Black Colleges and Universities (HBCUs), and Hispanic-serving institutions.
Are faith-based or community-based organizations eligible?
Yes. The FOA explicitly includes faith-based or community-based organizations among eligible applicants.
Can non-U.S. (foreign) entities apply?
Yes. The FOA indicates that non-U.S. (foreign) entities and regional organizations may be eligible.
Do U.S. territories or possessions fall under eligibility?
Yes. The FOA indicates that U.S. territories or possessions are included.
When was this FOA posted and when did it close?
Key administrative details indicate it was posted/created on May 7, 2010, with an original and current closing date of September 21, 2012, and an archive date of October 21, 2012.
Is PAR-10-191 currently active?
No. Based on the closing date (September 21, 2012) and archive date (October 21, 2012), the announcement is no longer active as written.
Why might this archived FOA still be useful?
Even though it is inactive, it can still serve as a record of NIH priorities and as a template for the kinds of vulvodynia-focused projects NIH has sought to fund under small-grant mechanisms.
Where was the full announcement hosted?
The full announcement was hosted on the NIH Grants Policy/Guide site.
Who should be contacted for help with access or technical issues?
NIH provided standard support contacts for access or technical issues, including GrantsInfo (301-435-0714) and the NIH Office of Extramural Research webmaster for linking problems.
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