Opportunity Information: Apply for PA 14 037
Apply for PA 14 037
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Women Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Dec 12, 2013 and posted on Dec 12, 2013.
- Applicants must submit their applications by Jan 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $100,000.00 in funding.
- Eligible applicants include: Public housing authorities/Indian housing authorities Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses City or township governments Native American tribal governments (Federally recognized) For profit organizations other than small businesses County governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Independent school districts State governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
Women Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R03) is a National Institutes of Health (NIH) discretionary grant opportunity (Funding Opportunity Number PA-14-037) designed to push forward research that clarifies how and why substance use disorders differ between males and females, and to deepen understanding of addiction-related factors that are unique to women. The core aim is to strengthen the evidence base on sex- and gender-informed mechanisms involved in drug and alcohol abuse and dependence, ultimately supporting better prevention strategies, improved diagnostics, and more effective interventions that reflect real biological and social differences rather than assuming that findings from one group automatically generalize to another.
This announcement specifically invites small research projects under the NIH R03 mechanism, which is typically used for focused, exploratory, or pilot-style studies that can quickly generate new data or test a targeted hypothesis. In practical terms, the FOA is meant to help investigators gather early evidence, develop or refine methods, or establish proof-of-concept findings that can later justify larger-scale funding. The award ceiling listed for this opportunity is $100,000, and there is no cost sharing or matching requirement, which reduces barriers for applicants who may not have access to non-federal funds.
The scientific scope emphasizes two main priorities: (1) research on sex/gender differences in drug and alcohol abuse and addiction, and (2) research on determinants of substance use and addiction that are specific to women. The FOA makes clear that it is open to both human studies and animal model studies, signaling NIH interest in a full translational pipeline, from basic biological mechanisms to clinically relevant outcomes and population-level patterns. While the source description is brief, the topic area generally encompasses questions such as differences in vulnerability to initiation and escalation of use, progression from use to dependence, withdrawal and relapse processes, treatment response, the influence of hormones and reproductive transitions, sex-specific neurobiology and pharmacology, and gender-linked risk environments such as caregiving roles, trauma exposure, stigma, and access to care.
Administratively, this opportunity was posted on December 12, 2013, with an original and final closing date of January 7, 2017, and it was archived on February 7, 2017. Even though it is no longer open, the archived FOA remains useful as a reference point for the kinds of sex/gender-focused addiction research NIH has sought to stimulate, and it can help applicants shape future submissions to related NIH notices and active funding announcements in alcohol and drug abuse research.
The announcement is associated with the NIH funding activity areas of education and health and is tied to two Catalog of Federal Domestic Assistance (CFDA) program numbers: 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs). This pairing reflects the FOA’s broad coverage across both alcohol-related and other drug-related substance use disorders, rather than limiting the scope to one substance class.
Eligibility for this grant was expansive and intentionally inclusive. Eligible applicants included a wide range of domestic U.S. entities such as public and state-controlled institutions of higher education, private colleges and universities, nonprofit organizations with or without 501(c)(3) status (with the noted distinction for those that are institutions of higher education), for-profit organizations (including small businesses and other for-profits), local and state governments, independent school districts, special district governments, public housing authorities and Indian housing authorities, and multiple categories of tribal governments and tribal organizations. The FOA also explicitly allowed non-U.S. participation: non-domestic (foreign) organizations and foreign institutions were eligible to apply, non-domestic components of U.S. organizations were eligible, and foreign components were allowed as defined in the NIH Grants Policy Statement. It also called out categories of institutions that NIH often highlights to encourage broad participation and capacity building, including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based and community-based organizations and eligible federal agencies.
For applicants or readers wanting full details, NIH provided an official Additional Information link to the FOA text hosted on the NIH grants policy/guide site (http://grants.nih.gov/grants/guide/pa-files/PA-14-037.html). The contact information listed for access or linking issues directs users to the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, which is consistent with NIH’s centralized support for electronic FOA access and technical navigation problems.
Overall, PA-14-037 was a targeted NIH small-grant opportunity aimed at strengthening sex- and gender-aware addiction science, with an emphasis on women-specific factors and comparative male-female differences, supporting both human and animal research, offering up to $100,000 without matching requirements, and maintaining broad eligibility that included academic, nonprofit, governmental, for-profit, tribal, and foreign organizations.
Frequently Asked Questions (FAQs)
What is the name of this grant opportunity?
The opportunity is titled "Women Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R03)."
What is the Funding Opportunity Number (FON) for this announcement?
The Funding Opportunity Number is PA-14-037.
Which federal agency is offering this opportunity?
This is a discretionary grant opportunity from the National Institutes of Health (NIH).
What is the main purpose of PA-14-037?
The purpose is to advance research that clarifies how and why substance use disorders differ between males and females, and to strengthen understanding of addiction-related factors that are unique to women. The overall goal is to improve prevention strategies, diagnostics, and interventions by accounting for real biological and social differences rather than assuming findings generalize across groups.
What type of NIH grant mechanism is used for this opportunity?
This FOA uses the NIH R03 mechanism, which is typically intended for small research projects that are focused, exploratory, or pilot-style in nature.
What kinds of projects are typically a fit for an NIH R03 under this FOA?
Projects that can quickly generate new data or test a targeted hypothesis are the best fit. The FOA is positioned to help investigators gather early evidence, develop or refine methods, or establish proof-of-concept findings that could support later, larger-scale applications.
What is the maximum award amount listed for this opportunity?
The award ceiling listed is $100,000.
Is cost sharing or matching required?
No. The announcement states there is no cost sharing or matching requirement.
What are the main scientific priorities in the scope of this FOA?
The FOA emphasizes two priorities: (1) research on sex/gender differences in drug and alcohol abuse and addiction, and (2) research on determinants of substance use and addiction that are specific to women.
Does the FOA focus only on women, or does it also include male-female comparisons?
It includes both. The scope explicitly covers sex/gender differences between males and females, while also highlighting determinants and mechanisms that are specific to women.
Are human studies allowed under this announcement?
Yes. The announcement indicates it is open to human studies.
Are animal model studies allowed under this announcement?
Yes. The announcement indicates it is open to animal model studies as well, reflecting interest across the translational pipeline.
What general topic areas does the FOA intend to stimulate (as reflected in the description)?
Based on the description provided, the topic area generally encompasses questions such as differences in vulnerability to initiation and escalation of use, progression from use to dependence, withdrawal and relapse processes, treatment response, the influence of hormones and reproductive transitions, sex-specific neurobiology and pharmacology, and gender-linked risk environments such as caregiving roles, trauma exposure, stigma, and access to care.
When was this funding opportunity posted?
It was posted on December 12, 2013.
What were the closing dates for applications under this FOA?
The original and final closing date listed was January 7, 2017.
Is PA-14-037 currently open for applications?
No. The FOA is no longer open. It was archived on February 7, 2017.
If it is archived, is the FOA still useful?
Yes. Even though it is no longer open, the archived FOA can still be used as a reference for the types of sex/gender-focused addiction research NIH has sought to stimulate, and it may help applicants shape future submissions to related NIH notices and active funding announcements.
Which NIH funding activity areas are associated with this opportunity?
The announcement is associated with the NIH funding activity areas of education and health.
Which CFDA program numbers are connected to this FOA?
The FOA is tied to CFDA 93.273 (Alcohol Research Programs) and CFDA 93.279 (Drug Abuse and Addiction Research Programs).
Does this opportunity cover alcohol only, drugs only, or both?
It covers both alcohol-related and other drug-related substance use disorders, as reflected by the two CFDA program numbers and the stated scope.
Who was eligible to apply (in general terms)?
Eligibility was broad and intentionally inclusive. It included many types of U.S. organizations (academic, nonprofit, for-profit, governmental, tribal, and other public entities) and also allowed non-U.S. participation, including foreign organizations and institutions, non-domestic components of U.S. organizations, and foreign components as defined in the NIH Grants Policy Statement.
Are U.S. colleges and universities eligible?
Yes. Eligible applicants included public and state-controlled institutions of higher education and private colleges and universities.
Are nonprofit organizations eligible?
Yes. Nonprofit organizations were eligible, including those with or without 501(c)(3) status (with a distinction noted for those that are institutions of higher education).
Are for-profit organizations eligible?
Yes. For-profit organizations, including small businesses and other for-profits, were eligible.
Are local and state government entities eligible?
Yes. Eligible applicants included local governments and state governments, as well as independent school districts and special district governments.
Are public housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities were listed as eligible applicants.
Are tribal governments and tribal organizations eligible?
Yes. Multiple categories of tribal governments and tribal organizations were included in the eligible applicant types.
Are foreign (non-U.S.) organizations eligible to apply?
Yes. The FOA explicitly allowed non-domestic (foreign) organizations and foreign institutions to apply.
Can a U.S. organization include a non-U.S. component in the project?
Yes. Non-domestic components of U.S. organizations were eligible, and foreign components were allowed as defined in the NIH Grants Policy Statement.
Did NIH encourage participation from specific institution types?
Yes. The FOA called out categories of institutions NIH often highlights to encourage broad participation, including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). It also noted faith-based and community-based organizations and eligible federal agencies.
Where can someone find the official FOA text?
The official Additional Information link provided for the FOA text is: http://grants.nih.gov/grants/guide/pa-files/PA-14-037.html
Who should be contacted for problems accessing the FOA link or related technical navigation issues?
The contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What is the central research theme emphasized by this announcement?
The central theme is sex- and gender-informed addiction science, with specific emphasis on women-specific factors and on differences between males and females in drug and alcohol abuse/dependence.
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