Opportunity Information: Apply for PA 14 036
Apply for PA 14 036
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Women Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Dec 12, 2013 and posted on Dec 12, 2013.
- Applicants must submit their applications by Jan 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses City or township governments Special district governments County governments State governments Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIH grant opportunity titled "Women Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R21)" (Funding Opportunity Number PA-14-036) is a discretionary research grant announcement designed to push forward what is known about how sex and gender shape substance use, abuse, dependence, and addiction. The central aim is to encourage studies that directly examine differences between males and females in drug and alcohol-related behaviors and outcomes, while also supporting research that focuses on factors that are unique to or especially relevant for women. In practice, this means the NIH is looking for projects that can clarify why women and men may initiate use differently, progress to problematic use at different rates, experience different health or psychiatric consequences, or respond differently to prevention and treatment approaches. The FOA explicitly welcomes both human studies and animal model studies, signaling that the program is open to a wide range of approaches, from clinical and epidemiological work to laboratory-based mechanistic research.
This opportunity uses the NIH R21 mechanism, which is typically intended for exploratory and developmental work. That emphasis makes it a good fit for early-stage or higher-risk ideas that could open up new research directions on sex/gender differences in addiction, generate preliminary data, or test innovative hypotheses that are not yet ready for a larger, longer R01-style project. The listing provides an award ceiling of $200,000, reflecting a modest budget cap consistent with the R21 structure and its role in supporting pilot and proof-of-concept efforts rather than large-scale multi-year trials.
The program falls under health-related federal assistance and is connected to two CFDA program areas: 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs). In other words, applications can focus on alcohol, drugs, or both, as long as the work squarely addresses the FOA theme of sex/gender differences and women-specific factors in abuse/dependence and addiction. The sponsoring agency is the National Institutes of Health, and the core scientific mission described in the announcement is to advance research in this space rather than fund service delivery or training programs.
Eligibility is broad and includes a wide spectrum of organizations. Academic institutions are eligible, including public and state-controlled universities and private institutions of higher education. A variety of nonprofit entities are eligible, including 501(c)(3) organizations and nonprofits without 501(c)(3) status (as long as they are not institutions of higher education in that category). For-profit organizations may apply, including small businesses and other for-profit entities that are not classified as small businesses. Government applicants are also eligible at multiple levels, including state, county, city/township, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The FOA also makes room for tribal participation, including federally recognized tribal governments and other tribal organizations, as well as tribally controlled colleges and universities.
The additional eligibility language underscores NIH's intent to be inclusive of institutions that serve historically underrepresented communities and regions. This includes HBCUs, Hispanic-serving institutions, AANAPISIS institutions, Alaska Native and Native Hawaiian-serving institutions, and other similar organizations. Faith-based and community-based organizations are also listed as eligible, along with eligible federal agencies. Importantly, the FOA allows non-U.S. participation: non-domestic (non-U.S.) entities and foreign institutions may apply, non-domestic components of U.S. organizations are eligible, and foreign components are allowed as defined by NIH policy. This is a meaningful feature for research questions where international comparisons, cross-cultural gender norms, or population differences might be scientifically valuable, or where specialized expertise and resources are located outside the United States.
The opportunity does not require cost sharing or matching funds, which generally lowers the barrier to entry for smaller organizations or projects that are exploratory in nature. From an administrative standpoint, the announcement was posted on December 12, 2013, with an original and current closing date of January 7, 2017, and an archive date of February 7, 2017, meaning the specific FOA is no longer active but remains a useful reference point for the kinds of projects NIH has sought in this area and for locating successor announcements with similar priorities.
For applicants or readers who need the full official language, the FOA is linked through the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PA-14-036.html. The contact point provided in the source data is the NIH Office of Extramural Research (OER) webmaster for technical difficulties accessing or linking to the announcement (FBOWebmaster@OD.NIH.GOV), which is mainly a support channel for access issues rather than scientific or programmatic questions about fit.
In plain terms, this FOA was a targeted NIH effort to stimulate innovative, relatively fast-moving research that can explain and address how addiction-related risks, trajectories, consequences, and potentially responses to interventions differ by sex and gender, with special emphasis on women and on scientifically grounded explanations that can be tested in humans and in animal models.
Frequently Asked Questions (FAQs)
What is the title of this NIH grant opportunity?
The opportunity is titled "Women Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R21)".
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is PA-14-036.
Which agency is sponsoring this funding opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
What is the main purpose of this FOA?
This FOA is designed to advance research on how sex and gender shape substance use, abuse, dependence, and addiction. It encourages studies that directly examine differences between males and females and also supports research on factors that are unique to or especially relevant for women.
What kinds of scientific questions is NIH trying to stimulate with this FOA?
Projects under this FOA are meant to clarify why women and men may differ in:
- How they initiate drug or alcohol use
- How quickly they progress to problematic use
- The health or psychiatric consequences they experience
- How they respond to prevention and treatment approaches
Does the FOA focus only on women?
The FOA has a strong emphasis on women and women-relevant factors, but it also explicitly encourages research that directly compares males and females to understand sex/gender differences in substance-related behaviors and outcomes.
Are both drug and alcohol topics allowed?
Yes. Applications can focus on alcohol, drugs, or both, as long as the project squarely addresses sex/gender differences and/or women-specific factors in abuse/dependence and addiction.
What research approaches are acceptable under this FOA?
The FOA welcomes a wide range of approaches, including:
- Human studies (for example, clinical or epidemiological research)
- Animal model studies (for example, laboratory-based mechanistic research)
What grant mechanism does this FOA use?
This opportunity uses the NIH R21 mechanism.
What does it mean that this is an R21 opportunity?
Based on the description provided, the R21 mechanism is intended for exploratory and developmental projects. It is positioned as a good fit for early-stage or higher-risk ideas that can open new research directions, generate preliminary data, or test innovative hypotheses that are not yet ready for a larger, longer R01-style project.
Is there a budget cap for awards under this FOA?
Yes. The listing provides an award ceiling of $200,000, consistent with the R21 structure and its role in supporting pilot or proof-of-concept efforts rather than large-scale multi-year trials.
What CFDA program areas are associated with this opportunity?
This FOA is connected to two CFDA program areas:
- 93.273 (Alcohol Research Programs)
- 93.279 (Drug Abuse and Addiction Research Programs)
What type of federal assistance is this?
It is described as a health-related federal assistance opportunity.
Is this funding intended for research, training, or service delivery?
The core mission described is to advance research in sex/gender differences in addiction. It is not described as funding service delivery or training programs.
What organizations are eligible to apply?
Eligibility is described as broad and includes many organization types, such as:
- Academic institutions (public/state-controlled universities and private institutions of higher education)
- Nonprofit organizations (including 501(c)(3) organizations and nonprofits without 501(c)(3) status, as long as they are not institutions of higher education in that category)
- For-profit organizations (including small businesses and other for-profit entities not classified as small businesses)
- Government entities (state, county, city/township, special district governments, independent school districts, and public housing authorities/Indian housing authorities)
- Tribal entities (federally recognized tribal governments, other tribal organizations, and tribally controlled colleges and universities)
Are institutions serving historically underrepresented communities specifically included in eligibility?
Yes. The eligibility language explicitly includes a range of institutions that serve historically underrepresented communities and regions, including:
- HBCUs
- Hispanic-serving institutions
- AANAPISIS institutions
- Alaska Native and Native Hawaiian-serving institutions
- Other similar organizations
Are faith-based or community-based organizations eligible?
Yes. Faith-based and community-based organizations are listed as eligible.
Can federal agencies apply?
Yes. Eligible federal agencies are listed among eligible applicants.
Are non-U.S. (foreign) organizations allowed to apply?
Yes. The FOA allows non-U.S. participation, including:
- Non-domestic (non-U.S.) entities and foreign institutions
- Non-domestic components of U.S. organizations
- Foreign components as defined by NIH policy
Does this FOA require cost sharing or matching funds?
No. The opportunity states that it does not require cost sharing or matching funds.
When was this FOA posted?
The announcement was posted on December 12, 2013.
What were the closing date and archive date for this FOA?
The original and current closing date listed is January 7, 2017, and the archive date is February 7, 2017.
Is this specific FOA currently active?
No. Based on the closing and archive dates provided, this specific FOA is no longer active, though it may remain useful as a reference point for NIH interests in this research area and for identifying successor announcements with similar priorities.
Where can I find the official FOA text?
The FOA is linked through the NIH grants guide at: http://grants.nih.gov/grants/guide/pa-files/PA-14-036.html
Who is the contact listed, and what are they for?
The contact point provided is the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV) for technical difficulties accessing or linking to the announcement, rather than scientific or programmatic questions about fit.
What is the opportunity described as in plain terms?
It is described as a targeted NIH effort to stimulate innovative, relatively fast-moving research that explains and addresses how addiction-related risks, trajectories, consequences, and potential responses to interventions differ by sex and gender, with special emphasis on women, using both human and animal model research where appropriate.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 14 036) also looked into and applied for these:
| Funding Opportunity |
|---|
| Women Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R03) Apply for PA 14 037 Funding Number: PA 14 037 Agency: National Institutes of Health Category: Education Health Funding Amount: $100,000 |
| Women Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R01) Apply for PA 14 038 Funding Number: PA 14 038 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Early Stage Innovative Molecular Analysis Technology Development for Cancer Research (R21) Apply for RFA CA 14 003 Funding Number: RFA CA 14 003 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Early Stage Development of Innovative Technologies for Biospecimen Science (R21) Apply for RFA CA 14 005 Funding Number: RFA CA 14 005 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Validation and Advanced Development of Emerging Technologies for Biospecimen Science (R33) Apply for RFA CA 14 006 Funding Number: RFA CA 14 006 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
| Validation and Advanced Development of Emerging Molecular Analysis Technologies for Cancer Research (R33) Apply for RFA CA 14 004 Funding Number: RFA CA 14 004 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
| Using Social Media to Understand and Address Substance Use and Addiction (R01) Apply for RFA CA 14 008 Funding Number: RFA CA 14 008 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Using Social Media to Understand and Address Substance Use and Addiction (R21) Apply for RFA CA 14 009 Funding Number: RFA CA 14 009 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R01) Apply for PA 14 061 Funding Number: PA 14 061 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R21) Apply for PA 14 062 Funding Number: PA 14 062 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R03) Apply for PA 14 063 Funding Number: PA 14 063 Agency: National Institutes of Health Category: Education Health Funding Amount: $100,000 |
| Fundamental Mechanisms of Affective and Decisional Processes in Cancer Control (U01) Apply for PAR 14 067 Funding Number: PAR 14 067 Agency: National Institutes of Health Category: Education Health Funding Amount: $700,000 |
| Centers of Excellence in Self Management Building Research Teams for the Future (P20) Apply for RFA NR 14 001 Funding Number: RFA NR 14 001 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
| Centers of Excellence in Self Management Research (P30) Apply for RFA NR 14 002 Funding Number: RFA NR 14 002 Agency: National Institutes of Health Category: Education Health Funding Amount: $480,000 |
| Tools for Monitoring and Manipulating Modified RNAs in the Nervous System (R43/R44) Apply for RFA DA 15 001 Funding Number: RFA DA 15 001 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Tools for Monitoring and Manipulating Modified RNAs in the Nervous System (R41/R42) Apply for RFA DA 15 002 Funding Number: RFA DA 15 002 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Medications Development Centers of Excellence Cooperative Program (U54) Apply for RFA DA 15 003 Funding Number: RFA DA 15 003 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Neuroimmune Signaling in Substance Use Disorders (R01) Apply for PA 14 084 Funding Number: PA 14 084 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Neuroimmune Signaling and Function in Substance Use Disorders (R21) Apply for PA 14 083 Funding Number: PA 14 083 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Revision Applications for Research on Metabolic Reprogramming to Improve Immunotherapy (R01) Apply for PAR 14 085 Funding Number: PAR 14 085 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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