Opportunity Information: Apply for PA 09 174

  • The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Womens Mental Health in Pregnancy and the Postpartum Period (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.226 Research on Healthcare Costs, Quality and Outcomes 93.242 Mental Health Research Grants 93.279 Drug Abuse and Addiction Research Programs 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Apr 24, 2009 and posted on Apr 24, 2009.
  • Applicants must submit their applications by May 7, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments For profit organizations other than small businesses Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) County governments Public housing authorities/Indian housing authorities State governments Small businesses Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The funding opportunity titled "Womens Mental Health in Pregnancy and the Postpartum Period (R01)" (Funding Opportunity Number PA-09-174) is a National Institutes of Health discretionary grant announcement designed to support research focused on mental health issues affecting women during pregnancy and after childbirth. It is sponsored collaboratively by the National Institute of Mental Health (NIMH), the National Institute on Drug Abuse (NIDA), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), and the Agency for Healthcare Research and Quality (AHRQ). The central aim is to encourage rigorous scientific work that improves understanding of psychiatric conditions across the perinatal period, which the announcement defines broadly as spanning both pregnancy and the postpartum timeframe. The agencies highlight that while postpartum mental health crises have received public attention due to severe, highly visible outcomes, depression is also common during pregnancy, and therefore research that follows women throughout pregnancy and into the postpartum period is strongly encouraged.

A key motivation behind the announcement is the serious impact that untreated perinatal mental illnesses can have. The text points specifically to severe postpartum depression and postpartum psychosis, noting that when these conditions go untreated, the consequences can be devastating not only for the affected individual but also for infants, partners, extended families, and communities. By referencing an AHRQ evidence-based practice report that recognizes depression as prevalent during pregnancy as well as after delivery, the FOA signals interest in studies that capture onset, course, risk factors, detection, and outcomes across the full perinatal window rather than treating postpartum mental health as an isolated issue. Because multiple NIH institutes and AHRQ are involved, the scientific scope can reasonably include a wide range of approaches, such as clinical, epidemiological, health services, and intervention research, including work intersecting with substance use and addiction (given NIDA involvement), maternal and child development (given NICHD involvement), and care quality, outcomes, and healthcare delivery (given AHRQ involvement).

This particular announcement uses the NIH Research Project Grant (R01) mechanism, which typically supports more mature, hypothesis-driven projects with a defined research plan and sufficient preliminary basis to justify a full-scale study. The FOA also notes it runs in parallel with a separate, scientifically identical announcement, PA-09-175, which uses the R21 exploratory/developmental mechanism. Practically, that parallel structure means investigators can choose between an R01 for a larger, more comprehensive project or an R21 for earlier-stage, high-risk/high-reward work, depending on readiness and the amount of preliminary data. Awards under PA-09-174 are contingent on the availability of funds and on the submission of a sufficient number of meritorious applications, meaning there is no guaranteed number of awards and funding decisions depend on both appropriations and peer review outcomes.

From an administrative standpoint, the opportunity is categorized under broad public service areas including Education, Health, Income Security, and Social Services, and it references multiple CFDA numbers that reflect the participating agencies interests: 93.242 (Mental Health Research Grants), 93.279 (Drug Abuse and Addiction Research Programs), 93.865 (Child Health and Human Development Extramural Research), and 93.226 (Research on Healthcare Costs, Quality and Outcomes). The posted and creation date is April 24, 2009, with an original and current closing date listed as May 7, 2012, and an archive date of June 7, 2012, indicating the FOA is no longer active but remains available as a record of the initiative and its requirements. The announcement specifies there is no cost sharing or matching requirement, which is typical for many NIH research grants and reduces barriers for applicants that cannot provide non-federal matching funds.

Eligibility for this grant was intentionally broad, reflecting NIH policy to encourage diverse institutional participation. Eligible applicants included public and private institutions of higher education, nonprofit organizations (both with and without 501(c)(3) status, with certain distinctions), for-profit organizations other than small businesses, and small businesses. Government entities at multiple levels were also eligible, including state governments, county governments, city or township governments, special district governments, and public housing authorities/Indian housing authorities. Tribal entities were eligible in both federally recognized and other-than-federally-recognized categories, and the eligibility list also explicitly included U.S. territories or possessions. Additional eligible applicants named in the opportunity include Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, and even non-U.S. entities (foreign organizations), as well as eligible agencies of the federal government. Taken together, that eligibility language signals an interest in supporting research across many settings and populations, including communities that may be underserved or disproportionately affected by perinatal mental health challenges.

For reference and further detail, the full announcement was hosted through the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PA-09-174.html. The listed contact for access or technical issues was the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV), which is typical for archived FOAs.

Frequently Asked Questions (FAQs)

What is the title and funding opportunity number for this grant?

The opportunity is titled "Womens Mental Health in Pregnancy and the Postpartum Period (R01)" and the Funding Opportunity Number is PA-09-174.

Which federal agencies sponsored this funding opportunity?

This FOA was sponsored collaboratively by the National Institute of Mental Health (NIMH), the National Institute on Drug Abuse (NIDA), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), and the Agency for Healthcare Research and Quality (AHRQ).

What is the main goal of this funding opportunity?

The central aim is to support rigorous research that improves understanding of psychiatric conditions affecting women during pregnancy and the postpartum period, with particular encouragement for studies that follow women across pregnancy into the postpartum timeframe.

How does the FOA define the "perinatal period"?

In this announcement, the perinatal period is defined broadly to include both pregnancy and the postpartum timeframe.

Why does the FOA emphasize research that spans pregnancy through postpartum?

The announcement notes that postpartum mental health crises have received public attention due to severe outcomes, but it also highlights that depression is common during pregnancy. As a result, the agencies encourage research that captures onset, course, risk factors, detection, and outcomes across the full perinatal window rather than focusing only on postpartum.

Which mental health conditions are specifically mentioned as serious concerns?

The text specifically references severe postpartum depression and postpartum psychosis, emphasizing that untreated illness can have devastating consequences for the affected individual and for infants, partners, extended families, and communities.

What types of research approaches does this FOA appear to support?

Based on the participating agencies and the stated goals, the scope can reasonably include clinical, epidemiological, health services, and intervention research. The collaboration also suggests interest in work intersecting with substance use and addiction (NIDA), maternal and child development (NICHD), and healthcare quality, outcomes, and delivery (AHRQ).

What grant mechanism is used for PA-09-174?

PA-09-174 uses the NIH Research Project Grant (R01) mechanism, which typically supports more mature, hypothesis-driven projects with a defined research plan and sufficient preliminary basis for a full-scale study.

Is there a related opportunity using a different mechanism?

Yes. The FOA notes a parallel, scientifically identical announcement: PA-09-175, which uses the R21 exploratory/developmental mechanism.

How should an applicant decide between the R01 and the parallel R21?

The FOA describes the R01 as appropriate for larger, more comprehensive projects with a defined research plan and sufficient preliminary basis, while the parallel R21 is positioned for earlier-stage, exploratory or developmental work that may be higher-risk/high-reward and may require less preliminary data.

Are awards guaranteed under this funding opportunity?

No. Awards are contingent on the availability of funds and on the submission of a sufficient number of meritorious applications. This means there is no guaranteed number of awards, and funding decisions depend on appropriations and peer review outcomes.

What public service areas is this opportunity associated with?

The opportunity is categorized under broad public service areas including Education, Health, Income Security, and Social Services.

Which CFDA numbers are associated with this FOA?

The FOA references multiple CFDA numbers reflecting participating agency interests: 93.242 (Mental Health Research Grants), 93.279 (Drug Abuse and Addiction Research Programs), 93.865 (Child Health and Human Development Extramural Research), and 93.226 (Research on Healthcare Costs, Quality and Outcomes).

What were the posted and closing dates for this opportunity?

The posted/creation date is April 24, 2009. The original and current closing date is listed as May 7, 2012, and the archive date is June 7, 2012.

Is this funding opportunity still active?

No. Because the closing date is May 7, 2012 and the archive date is June 7, 2012, the FOA is no longer active and is available as an archived record of the initiative and its requirements.

Was cost sharing or matching required?

No. The announcement specifies that there is no cost sharing or matching requirement.

Who was eligible to apply?

Eligibility was broad and included public and private institutions of higher education; nonprofit organizations (with and without 501(c)(3) status, with certain distinctions); for-profit organizations other than small businesses; and small businesses. Government entities at multiple levels were eligible, including state, county, city or township, special district governments, and public housing authorities/Indian housing authorities.

Were Tribal entities and U.S. territories eligible applicants?

Yes. The eligibility list included federally recognized Tribal governments and other-than-federally-recognized Tribal entities, as well as U.S. territories or possessions.

Did the FOA explicitly include minority-serving institutions and community-based organizations?

Yes. The FOA explicitly listed Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). It also included faith-based or community-based organizations and regional organizations.

Were foreign organizations allowed to apply?

Yes. The eligibility language explicitly included non-U.S. entities (foreign organizations).

Were federal agencies eligible to apply?

Yes. The opportunity listed eligible agencies of the federal government among eligible applicants.

Where could applicants find the full archived announcement?

The full announcement was hosted through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PA-09-174.html.

Who was listed as the contact for access or technical issues?

The listed contact for access or technical issues was the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

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