Opportunity Information: Apply for W81XWH 12 NFRP IIRA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DOD FY12 Neurofibromatosis Investigator Initiated Research Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Mar 22, 2012 and posted on Mar 22, 2012.
  • Applicants must submit their applications by May 31, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $3,840,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 12 NFRP IIRA

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Opportunity Summary:

The DOD FY12 Neurofibromatosis (NF) Investigator Initiated Research Award (Funding Opportunity Number W81XWH-12-NFRP-IIRA) was a U.S. Department of Defense funding opportunity administered through the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA), under CFDA 12.420 (Military Medical Research and Development). It was designed to support investigator-driven projects in neurofibromatosis that are genuinely innovative and that can move the field forward in meaningful ways, either by improving scientific understanding of NF or by leading to better clinical tools and outcomes for people living with NF.

The program’s main goal was to fund basic and clinically oriented research that could shed light on how neurofibromatosis develops, including the biological mechanisms behind NF-associated lesions and other abnormalities. Beyond advancing knowledge, the award emphasized research likely to produce substantial improvements over existing approaches to diagnosis and treatment. In practical terms, strong applications would be expected to propose work that could change how NF is detected, monitored, or managed, and ultimately improve patient care. A consistent theme in the description is real-world impact: projects were expected to have a clear line of sight to improving quality of life for individuals affected by NF, rather than being purely incremental or narrowly descriptive.

In terms of award structure, funding could be provided as either a grant or a cooperative agreement, indicating that some projects might involve more active programmatic involvement or coordination by the government depending on the nature of the work. The opportunity fell under the broader category of science, technology, and other research and development. Cost sharing or matching funds were not required, lowering barriers for institutions and investigators that might not have additional resources to contribute.

The anticipated scale of the competition was relatively small and selective. The announcement projected approximately 4 awards with an estimated total funding level of $3,840,000. Eligibility was described as “unrestricted,” meaning it was open to any type of entity, subject to any additional eligibility details that might have been included in the full announcement. This typically allows participation from a wide range of applicants such as universities, nonprofit research organizations, small businesses, and other qualified institutions.

Key dates show that the opportunity was posted on March 22, 2012, with an application deadline of May 31, 2012. The listing was later archived on June 30, 2012, signaling the end of that funding cycle. For applicant support, the announcement directed people having trouble accessing the full posting to contact the CDMRP Help Desk (help@cdmrp.org, 301-682-5507), reflecting standard DOD/CDMRP administrative support channels for electronic submission and retrieval issues.

Overall, this award mechanism was built to stimulate new, high-impact NF research ideas, with an emphasis on work that could translate into better diagnostics, therapies, and patient outcomes, while supporting both foundational biology and clinically relevant investigation.

FAQs: DOD FY12 Neurofibromatosis (NF) Investigator Initiated Research Award (W81XWH-12-NFRP-IIRA)

What is the name of this funding opportunity?

The opportunity is the DOD FY12 Neurofibromatosis (NF) Investigator Initiated Research Award (IIRA), Funding Opportunity Number W81XWH-12-NFRP-IIRA.

Which agency offered and administered the award?

It was a U.S. Department of Defense opportunity administered through the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA).

What CFDA program was this associated with?

This opportunity was under CFDA 12.420, Military Medical Research and Development.

What research area did the award focus on?

The award focused on investigator-driven research in neurofibromatosis (NF), including both basic and clinically oriented studies intended to move the field forward in meaningful ways.

What was the main goal of the program?

The main goal was to fund research that could improve scientific understanding of NF and/or lead to better clinical tools and outcomes for people living with NF, with a consistent emphasis on real-world impact.

What kinds of projects were the program trying to support?

The program aimed to support genuinely innovative projects that could advance knowledge about how neurofibromatosis develops, including biological mechanisms behind NF-associated lesions and other abnormalities, while also encouraging work that could improve diagnosis and treatment.

Was translational or patient-impact research emphasized?

Yes. The description emphasized projects with a clear line of sight to improvements in how NF is detected, monitored, or managed, and ultimately to improved patient care and quality of life.

Did the program prioritize incremental studies or major advances?

The opportunity emphasized genuinely innovative work expected to produce substantial improvements over existing approaches, rather than purely incremental or narrowly descriptive research.

What broad category did this opportunity fall under?

The opportunity was categorized under science, technology, and other research and development.

What type of funding instrument was used?

Funding could be provided either as a grant or as a cooperative agreement.

What does it mean that awards could be grants or cooperative agreements?

It indicates that some projects might involve more active programmatic involvement or coordination by the government depending on the nature of the work.

Was cost sharing or matching required?

No. Cost sharing or matching funds were not required.

How many awards were anticipated?

The announcement projected approximately 4 awards.

What was the estimated total funding level?

The estimated total funding level was $3,840,000.

Who was eligible to apply?

Eligibility was described as unrestricted, meaning it was open to any type of entity, subject to any additional eligibility details that may have been included in the full announcement.

What does "unrestricted eligibility" generally imply for applicants?

Based on the description, unrestricted eligibility typically allows participation from a wide range of applicants such as universities, nonprofit research organizations, small businesses, and other qualified institutions.

When was the opportunity posted?

It was posted on March 22, 2012.

What was the application deadline?

The application deadline was May 31, 2012.

When was the listing archived, and what does that indicate?

The listing was archived on June 30, 2012, which signaled the end of that particular funding cycle.

What should someone do if they had trouble accessing the full posting?

The announcement directed applicants to contact the CDMRP Help Desk for access issues.

What are the CDMRP Help Desk contact details provided?

Email: help@cdmrp.org. Phone: 301-682-5507.

What was the overall intent of this award mechanism?

It was intended to stimulate new, high-impact NF research ideas, supporting both foundational biology and clinically relevant investigation, with an emphasis on better diagnostics, therapies, and patient outcomes.

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