Opportunity Information: Apply for W81XWH 09 PRCRP SIA
Apply for W81XWH 09 PRCRP SIA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Cancer Synergistic Idea Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Aug 29, 2009 and posted on Jun 25, 2009.
- Applicants must submit their applications by Dec 9, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,750,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Peer Reviewed Cancer Research Program (PRCRP) Synergistic Idea Award (FY09) is a Department of the Army/USAMRAA funding opportunity focused exclusively on pediatric brain tumors within the broader field of childhood cancer. Projects must stay within this topic area; proposals that drift into other cancer areas are not responsive. Within pediatric brain tumor research, the program places special emphasis on rare pediatric brain tumors and expects applicants to use comprehensive approaches for collecting both tumor data and host data, reflecting an interest in understanding the disease in the context of the whole patient over time.
Scientifically, proposals are expected to align with at least one of three stated FY09 focus areas for pediatric brain tumors. These include: (1) distinguishing the biological drivers of tumors from processes involved in normal brain development, which speaks to separating cancer-causing mechanisms from normal developmental pathways; (2) creating novel tools and models that help close knowledge gaps around genetic predisposition, tumor initiation, and environmental contributors, signaling interest in better experimental systems and risk frameworks; and (3) improving understanding of the risks and consequences of therapeutic interventions on the host and how those risks connect to long-term outcomes, emphasizing survivorship, late effects, and treatment-related harm alongside effectiveness. The program is open to basic, preclinical, behavioral, and epidemiological research, as long as it clearly maps back to one or more of these focus areas.
A defining feature of the Synergistic Idea Award is its required team structure. Each funded project must be jointly designed and carried out by a collaboration of two to four independent, faculty-level (or equivalent) Principal Investigators who bring complementary expertise. The intent is that the team’s combined perspectives create real synergy: the application must show that the work can progress faster or reach outcomes that would not be achievable if each investigator pursued separate, parallel projects. The program explicitly encourages multidisciplinary and multi-institutional collaborations, and it supports both newly formed partnerships and existing research alliances, provided the collaboration is central to the scientific plan rather than incidental.
Administratively, although the investigators develop one shared scientific project, each participating PI must submit a separate application and, if selected, each PI receives an individual award. Applications must include clear, practical plans for how the team will work together across investigators and institutions, including ongoing communication routines, coordination of research activities and milestones, sharing of results, and mechanisms for data transfer. For multi-institution projects, an intellectual property plan is required to address potential ownership and material-sharing issues ahead of time and to reduce institutional barriers that could undermine cooperation or delay progress.
In terms of funding mechanics, this opportunity (Funding Opportunity Number W81XWH-09-PRCRP-SIA) was offered as a discretionary cooperative agreement/grant under CFDA 12.420 (Military Medical Research and Development), with no cost-sharing requirement. The program anticipated making 1 award with an estimated total funding level of $1,750,000. Eligibility was listed as unrestricted (open to any type of entity, subject to details in the full announcement). Key dates included a posted date of June 25, 2009 and an application closing date of December 9, 2009 (with the archive date listed as January 8, 2010). Contact support was provided through the CDMRP help resources for both announcement access and electronic submission assistance.
PRCRP Synergistic Idea Award (FY09) - FAQ
What is this grant opportunity?
This opportunity is the Department of Defense (DoD) Peer Reviewed Cancer Research Program (PRCRP) Synergistic Idea Award (FY09), administered through the Department of the Army/USAMRAA. The Funding Opportunity Number is W81XWH-09-PRCRP-SIA.
What topic area does this award support?
The award is focused exclusively on pediatric brain tumors within the broader field of childhood cancer. Applications must remain within pediatric brain tumor research to be considered responsive.
Are proposals in other childhood cancer areas allowed?
No. Proposals that drift into other cancer areas are described as not responsive to this opportunity.
Is there any special emphasis within pediatric brain tumors?
Yes. The program places special emphasis on rare pediatric brain tumors.
What kind of data collection approach is the program looking for?
The opportunity expects comprehensive approaches that collect both tumor data and host data, reflecting an interest in understanding disease in the context of the whole patient over time.
What are the FY09 focus areas for pediatric brain tumor research under this award?
Proposed research is expected to align with at least one of these three focus areas:
- Distinguishing biological drivers of tumors from processes involved in normal brain development.
- Creating novel tools and models to close knowledge gaps around genetic predisposition, tumor initiation, and environmental contributors.
- Improving understanding of risks and consequences of therapeutic interventions on the host and how those risks connect to long-term outcomes.
Do applications have to fit all three focus areas?
No. Proposals are expected to align with at least one of the three stated FY09 focus areas.
What types of research are allowed (basic, clinical, etc.)?
The program is open to basic, preclinical, behavioral, and epidemiological research, as long as the work clearly maps back to one or more of the FY09 focus areas.
What makes the Synergistic Idea Award different from other awards?
A defining feature is the required team structure and the emphasis on synergy. The project must be jointly designed and executed by a collaboration of two to four independent, faculty-level (or equivalent) Principal Investigators (PIs) with complementary expertise.
How many Principal Investigators are required?
Each funded project must include a team of two to four independent, faculty-level (or equivalent) Principal Investigators.
Do the PIs need to have different areas of expertise?
Yes. The opportunity specifies that the collaborating PIs should bring complementary expertise, with the goal that their combined perspectives create meaningful synergy.
What does the program mean by "synergy"?
The application must demonstrate that the work will progress faster or reach outcomes that would not be achievable if each investigator pursued separate, parallel projects.
Are multidisciplinary collaborations encouraged?
Yes. The program explicitly encourages multidisciplinary collaborations.
Are multi-institution collaborations allowed or encouraged?
Yes. Multi-institutional collaborations are explicitly encouraged, and the application must include practical plans for coordination across investigators and institutions.
Can newly formed teams apply, or only established collaborations?
Both are supported. The program supports newly formed partnerships as well as existing research alliances, as long as the collaboration is central to the scientific plan rather than incidental.
How is the application submitted if there are multiple PIs on one project?
Although the investigators develop one shared scientific project, each participating PI must submit a separate application.
How are awards made if the project is selected for funding?
If selected, each PI receives an individual award, even though the team is carrying out a shared scientific project.
What coordination or management details are expected in the application?
Applications must include clear, practical plans describing how the team will work together, including ongoing communication routines, coordination of research activities and milestones, sharing of results, and mechanisms for data transfer.
Is an intellectual property (IP) plan required?
For multi-institution projects, an intellectual property plan is required to address potential ownership and material-sharing issues in advance and reduce barriers that could undermine cooperation or delay progress.
What is the funding mechanism for this opportunity?
This opportunity was offered as a discretionary cooperative agreement/grant.
What CFDA number is associated with this grant?
The CFDA number listed is 12.420 (Military Medical Research and Development).
Is cost sharing required?
No. The opportunity states that there is no cost-sharing requirement.
How many awards were anticipated, and what was the estimated total funding?
The program anticipated making 1 award with an estimated total funding level of $1,750,000.
Who is eligible to apply?
Eligibility was listed as unrestricted (open to any type of entity), subject to details in the full announcement.
What are the key dates for this opportunity?
The posted date was June 25, 2009. The application closing date was December 9, 2009. The archive date was January 8, 2010.
Where can applicants get help with the announcement or electronic submission?
Support was provided through CDMRP help resources for both announcement access and electronic submission assistance.
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