Opportunity Information: Apply for RFA CK 11 0010501SUPP15
Apply for RFA CK 11 0010501SUPP15
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Epi Centers for the Prevention of Healthcare Associated Infections, Antimicrobial Resistance and Adverse Events A Multicenter Program Expansion (U54)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084 Prevention of Disease, Disability, and Death by Infectious Diseases.
- This funding opportunity was created on Dec 24, 2014 and posted on Dec 9, 2014.
- Applicants must submit their applications by Jan 23, 2015 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $4,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $800,000.00 in funding.
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- Additional Information on Eligibility The following organizations are eligible to apply bull Harvard Pilgrim Healthcare, Inc. bull Duke University bull Washington University bull University of Pennsylvania bull Hektoen Institute for Medical Research
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Opportunity Summary:
This CDC funding opportunity expands the Prevention Epicenters Program into a larger multicenter effort focused on reducing healthcare-associated infections (HAIs), slowing antimicrobial resistance (AR), and preventing other adverse events across U.S. healthcare settings. The core idea is to take promising discoveries and approaches that may have been developed through basic science, epidemiology, or technology work and move them into real-world, scalable prevention strategies that can be implemented and tested in multiple facilities. By emphasizing multicenter evaluation, the program aims to produce evidence that is more generalizable than single-site studies and more useful for broad adoption across different types of hospitals and care environments.
The award mechanism is a cooperative agreement (U54), meaning the CDC is expected to be actively involved with recipients rather than serving only as a passive funder. This structure typically supports close collaboration on study design, implementation, data collection, and evaluation so that the funded work aligns with national prevention priorities and produces results that can inform practice and policy. The focus is explicitly on epidemiologically grounded strategies to improve healthcare quality and patient safety, and it encourages translation: moving from discovery and early testing into interventions that can be deployed, assessed, and refined at scale. Strategies supported could include, for example, approaches that are already being investigated in single-center Epicenters projects and now need multicenter testing to confirm effectiveness, feasibility, and impact in varied settings.
The opportunity was offered by the Centers for Disease Control and Prevention under CFDA 93.084 (Prevention of Disease, Disability, and Death by Infectious Diseases). It is a discretionary funding opportunity in the health category, with an estimated total funding amount of $4,000,000 and an expectation of approximately five awards. Individual awards were anticipated to range from a floor of $200,000 to a ceiling of $800,000, and there was no cost-sharing or matching requirement, reducing financial barriers for participating institutions while keeping the focus on rigorous implementation and evaluation.
Eligibility was limited and specific. The announcement lists the eligible applicants as Harvard Pilgrim Healthcare, Inc., Duke University, Washington University, the University of Pennsylvania, and the Hektoen Institute for Medical Research. This indicates the funding was structured as a targeted expansion among designated Epicenters partners rather than an open competition to all organizations. The intent appears to be building on existing Epicenters infrastructure and expertise to quickly execute multicenter projects, coordinate protocols, and generate higher-confidence findings relevant to national HAI and AR prevention efforts.
Key dates show the posting date as December 9, 2014, with an original closing date of January 16, 2015, and a revised current closing date of January 23, 2015. Applications were required to be submitted electronically by 5:00 p.m. Eastern Time on the due date, and the opportunity was later archived on February 22, 2015. The official funding opportunity number is RFA CK 11 0010501SUPP15. For access issues related to the full announcement, the contact listed was Sharnell Wilson at zcq8@cdc.gov, with additional details referenced through Grants.gov.
Frequently Asked Questions (FAQs)
What is the purpose of this CDC funding opportunity?
This opportunity expands the CDC Prevention Epicenters Program into a larger multicenter effort aimed at reducing healthcare-associated infections (HAIs), slowing antimicrobial resistance (AR), and preventing other adverse events across U.S. healthcare settings. The emphasis is on moving promising discoveries and approaches into real-world, scalable prevention strategies that can be implemented and tested across multiple facilities.
What type of projects is this program trying to support?
The program supports epidemiologically grounded strategies to improve healthcare quality and patient safety, with a strong focus on translation. That means taking discoveries or approaches developed through basic science, epidemiology, or technology work and advancing them into interventions that can be deployed, evaluated, and refined at scale in real healthcare environments.
Why does the opportunity emphasize multicenter evaluation?
The intent of multicenter evaluation is to produce evidence that is more generalizable than single-site studies. Testing interventions in multiple facilities and varied care environments is meant to generate results that are more useful for broad adoption across different types of hospitals and healthcare settings.
What award mechanism is being used?
The award mechanism is a cooperative agreement (U54).
What does a cooperative agreement (U54) mean for the recipient?
A cooperative agreement indicates that CDC is expected to be actively involved with recipients rather than acting only as a passive funder. The description notes that this structure typically supports close collaboration on study design, implementation, data collection, and evaluation so the funded work aligns with national prevention priorities and produces results that can inform practice and policy.
What topic areas does the opportunity focus on?
The central focus areas are reducing healthcare-associated infections (HAIs), slowing antimicrobial resistance (AR), and preventing other adverse events across U.S. healthcare settings.
Are projects required to be epidemiologically grounded?
Yes. The opportunity explicitly focuses on epidemiologically grounded strategies intended to improve healthcare quality and patient safety.
Does the opportunity encourage translating early research into practice?
Yes. The opportunity encourages translation from discovery and early testing into interventions that can be deployed, assessed, and refined at scale.
Can strategies previously investigated in single-center Epicenters projects be supported?
Yes. The description gives an example that strategies already being investigated in single-center Epicenters projects could be supported when they are ready for multicenter testing to confirm effectiveness, feasibility, and impact in varied settings.
Who is offering this funding opportunity?
The opportunity is offered by the Centers for Disease Control and Prevention (CDC).
What is the CFDA number associated with this opportunity?
The CFDA is 93.084 (Prevention of Disease, Disability, and Death by Infectious Diseases).
Is this a discretionary funding opportunity and what category is it in?
Yes. It is described as a discretionary funding opportunity in the health category.
What is the estimated total funding amount?
The estimated total funding amount is $4,000,000.
How many awards are expected?
Approximately five awards were expected.
What is the anticipated range for individual award amounts?
Individual awards were anticipated to range from a floor of $200,000 to a ceiling of $800,000.
Is cost sharing or matching required?
No. There was no cost-sharing or matching requirement listed.
Who is eligible to apply?
Eligibility is limited to the following applicants named in the announcement: Harvard Pilgrim Healthcare, Inc.; Duke University; Washington University; the University of Pennsylvania; and the Hektoen Institute for Medical Research.
Is this an open competition for all organizations?
No. The eligibility list indicates it was structured as a targeted expansion among designated Epicenters partners rather than an open competition available to all organizations.
Why is eligibility limited to specific institutions?
Based on the description provided, the intent appears to be building on existing Prevention Epicenters infrastructure and expertise to execute multicenter projects quickly, coordinate protocols, and generate higher-confidence findings relevant to national HAI and AR prevention efforts.
What is the official funding opportunity number?
The official funding opportunity number is RFA CK 11 0010501SUPP15.
When was the opportunity posted?
The posting date was December 9, 2014.
What was the original application closing date?
The original closing date was January 16, 2015.
What was the revised (current) closing date?
The revised current closing date was January 23, 2015.
What time were applications due?
Applications were required to be submitted electronically by 5:00 p.m. Eastern Time on the due date.
Was the opportunity archived, and if so, when?
Yes. The opportunity was later archived on February 22, 2015.
How were applications required to be submitted?
Applications were required to be submitted electronically.
Where were additional details referenced?
Additional details were referenced through Grants.gov.
Who is the contact for access issues related to the full announcement?
The contact listed for access issues is Sharnell Wilson (zcq8@cdc.gov).
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