Opportunity Information: Apply for PAR 09 241
Apply for PAR 09 241
- The National Institutes of Health in the environment health income security and social services sector is offering a public funding opportunity titled "Genetic and Genomic Analysis of Xenopus (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.173 Research Related to Deafness and Communication Disorders 93.242 Mental Health Research Grants 93.837 Cardiovascular Diseases Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research 93.867 Vision Research.
- This funding opportunity was created on Jul 27, 2009 and posted on Jul 27, 2009.
- Applicants must submit their applications by Sep 30, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Small businesses Public and State controlled institutions of higher education City or township governments Private institutions of higher education Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) For profit organizations other than small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Genetic and Genomic Analysis of Xenopus (R21) opportunity (Funding Opportunity Number PAR-09-241) is an NIH grant announcement from the Eunice Kennedy Shriver National Institute of Child Health and Human Development that aims to push forward biomedical research that uses Xenopus (frog) as a vertebrate model system. The central focus is on investigator-initiated, exploratory projects that take advantage of Xenopus biology to improve how researchers find, study, and interpret genes, pathways, and phenotypes relevant to development and organ formation, as well as core cell biological processes such as cell division, signaling, and cell migration. In practical terms, the program is looking for work that either creates high-value genetic or genomic tools and resources for the broader Xenopus community, or that applies newer genetic/genomic approaches in Xenopus to open up new lines of inquiry, especially when those approaches have not been widely used in Xenopus research before.
This FOA is specifically aligned with the NIH R21 mechanism, which is meant for early-stage, high-risk/high-reward, developmental, or proof-of-concept efforts rather than long, incremental research plans. The announcement makes a clear distinction between what belongs in an R21 versus a traditional R01: projects that are long-term, expansive, or designed mainly to deepen knowledge in a well-established area are not considered a good fit for this mechanism. Instead, the expectation is that proposed studies will be novel and exploratory, will break new ground, and will extend prior discoveries toward new methods, directions, or applications in Xenopus-based genetics and genomics. The scientific scope runs in parallel with companion announcements using other mechanisms (an R01 and an R03) that cover the same general topic area, but this specific FOA is the one tailored to exploratory R21-style work.
From an administrative standpoint, the program is a discretionary grant opportunity under the National Institutes of Health. It was posted on July 27, 2009, with an original and final closing date of September 30, 2011, and it was archived on October 31, 2011. The listed award ceiling is $200,000, and there is no cost sharing or matching requirement, meaning applicants are not required to provide non-federal matching funds as a condition of the award.
Eligibility is broad and includes many types of organizations. Eligible applicants include public and private institutions of higher education, nonprofits (including 501(c)(3) and other nonprofit categories), small businesses, for-profit organizations other than small businesses, independent school districts, and multiple levels of government (state, county, city/township, special district), as well as public housing authorities and tribal governments and organizations (including federally recognized tribal governments). The eligibility language also explicitly includes a variety of additional organization types such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, faith-based and community-based organizations, U.S. territories or possessions, and even non-U.S. (foreign) entities and regional organizations, reflecting NIH’s generally inclusive applicant landscape for many research grants.
The announcement is associated with several CFDA program areas, indicating the broad relevance of Xenopus genetic/genomic tool development and application across multiple biomedical domains, including child health and human development as well as areas connected to environmental health, oral health, communication disorders, mental health, cardiovascular research, neuroscience and neurological disorders, and vision research. For further details, the FOA provided an NIH guide link to the full announcement and points of contact through the NIH Office of Extramural Research (OER) webmaster for access or technical issues.
FAQs: Genetic and Genomic Analysis of Xenopus (R21) - PAR-09-241
What is the Genetic and Genomic Analysis of Xenopus (R21) funding opportunity?
It is an NIH grant funding opportunity (Funding Opportunity Number PAR-09-241) from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). It supports biomedical research that uses Xenopus (frog) as a vertebrate model system, with an emphasis on genetics and genomics.
What is the main scientific goal of this FOA?
The goal is to advance Xenopus-based biomedical research by improving how researchers discover, analyze, and interpret genes, pathways, and phenotypes relevant to development and organ formation, as well as core cell biology processes like cell division, signaling, and cell migration.
What kind of projects does this FOA prioritize?
The FOA prioritizes investigator-initiated, exploratory projects that either (1) create high-value genetic or genomic tools and resources that benefit the broader Xenopus community, or (2) apply newer genetic/genomic approaches in Xenopus to open new research directions, especially when those approaches have not been widely used in Xenopus research before.
What does "investigator-initiated" mean in this context?
It means the proposed research ideas and approaches originate with the applicant investigator(s), rather than being defined by the agency as a highly prescriptive research plan. The FOA is designed to support creative, exploratory concepts within the stated Xenopus genetics/genomics scope.
What grant mechanism does this opportunity use?
This opportunity uses the NIH R21 mechanism, which is intended for exploratory, developmental, proof-of-concept, and potentially high-risk/high-reward studies.
How is an R21 different from an R01 according to this announcement?
The announcement draws a clear line: R21 projects should be novel and exploratory and aimed at breaking new ground, extending prior discoveries toward new methods, directions, or applications. Projects that are long-term, expansive, or primarily incremental (such as deepening knowledge in a well-established area) are described as a poor fit for the R21 mechanism and more consistent with an R01-type approach.
Are there related NIH announcements on the same topic?
Yes. The scientific scope is described as running in parallel with companion announcements using other mechanisms (an R01 and an R03) that cover the same general topic area. This specific FOA is the one tailored to exploratory R21-style work.
What model organism is the focus of this FOA?
The focus is Xenopus, a frog widely used as a vertebrate model system in biomedical research.
What scientific areas are specifically mentioned as relevant?
The FOA highlights development and organ formation and core cell biological processes such as cell division, signaling, and cell migration, with an overarching emphasis on genes, pathways, and phenotypes studied through genetic and genomic approaches in Xenopus.
Is the program aimed at tool/resource development, biological discovery, or both?
Both, as described. It explicitly seeks either the creation of high-value genetic/genomic tools and resources for the broader Xenopus community or the application of newer genetic/genomic approaches in Xenopus that enable new lines of inquiry.
What is the maximum award amount mentioned for this FOA?
The listed award ceiling is $200,000.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement, meaning applicants are not required to provide non-federal matching funds as a condition of the award.
Which agency and institute sponsor this opportunity?
It is a discretionary grant opportunity under the National Institutes of Health (NIH), issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
When was this funding opportunity posted?
It was posted on July 27, 2009.
What were the closing dates for this FOA?
The FOA listed an original closing date and a final closing date of September 30, 2011.
Is this FOA still active?
No. It was archived on October 31, 2011.
Who is eligible to apply?
Eligibility is broad and includes public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and other nonprofit categories); small businesses; for-profit organizations other than small businesses; independent school districts; and multiple levels of government (state, county, city/township, and special district). It also includes public housing authorities, tribal governments and organizations (including federally recognized tribal governments), and a range of other organization types explicitly named in the announcement.
Does the eligibility list explicitly include minority-serving institutions?
Yes. The eligibility language explicitly includes HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, and Alaska Native and Native Hawaiian serving institutions, among others.
Are faith-based and community-based organizations eligible?
Yes. The announcement explicitly includes faith-based and community-based organizations among eligible applicants.
Can organizations in U.S. territories or possessions apply?
Yes. The eligibility language explicitly includes U.S. territories or possessions.
Are non-U.S. (foreign) entities eligible?
Yes. The eligibility language explicitly includes non-U.S. (foreign) entities and regional organizations.
Does this FOA require that the applicant be a U.S. entity?
No. Based on the eligibility language provided, the announcement includes non-U.S. (foreign) entities and regional organizations, indicating that eligibility is not limited to U.S.-based applicants.
What CFDA program areas are associated with this announcement?
The announcement is associated with several CFDA program areas reflecting broad biomedical relevance. It references child health and human development and also areas connected to environmental health, oral health, communication disorders, mental health, cardiovascular research, neuroscience and neurological disorders, and vision research.
Where can applicants find the full FOA text and official details?
The FOA provided an NIH guide link to the full announcement. For access or technical issues, it referenced points of contact through the NIH Office of Extramural Research (OER) webmaster.
Is this opportunity described as competitive or discretionary?
It is described as a discretionary grant opportunity under the National Institutes of Health.
Browse more opportunities from the same category: Environment Health Income Security and Social Services
Next opportunity: Genetic and Genomic Analysis of Xenopus (R03)
Previous opportunity: Genetic and Genomic Analysis of Xenopus (R01)
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