Opportunity Information: Apply for PA 07 300
Apply for PA 07 300
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Hypersensitivity Pneumonitis Early Identification and Mechanisms of Disease (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.838 Lung Diseases Research.
- This funding opportunity was created on Dec 5, 2008 and posted on Jan 17, 2007.
- Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) County governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Small businesses Special district governments Independent school districts State governments For profit organizations other than small businesses City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Private institutions of higher education.
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:
The NIH funding opportunity announcement PA-07-300, titled "Hypersensitivity Pneumonitis - Early Identification and Mechanisms of Disease (R01)," supports research aimed at improving how hypersensitivity pneumonitis (HP) is recognized early and how its underlying immune-driven disease processes begin and progress. The core goal is to push the field beyond late-stage detection and toward earlier diagnosis, clearer disease classification, and a more complete understanding of the immune mechanisms involved in HP cause and pathogenesis. In practical terms, the opportunity is focused on studies that can clarify what triggers HP in different settings, how immune responses evolve over time, and what biological signals might help identify disease sooner, when interventions may be more effective.
This announcement uses the NIH R01 grant mechanism, which is the standard, full-scale research project format designed to support hypothesis-driven, investigator-initiated work. The FOA also notes that R01 funding can cover a range of project types, including pilot and feasibility efforts, small and self-contained projects, and work that develops or refines research technologies relevant to HP. That means the opportunity is not limited to one narrow study design; it can support foundational mechanistic immunology, translational studies connecting exposures to biological responses, and method or tool development that helps the community study HP more accurately and efficiently.
The eligibility criteria are broad and include many kinds of domestic and international organizations. Eligible applicants include public or state-controlled institutions of higher education, private institutions of higher education, nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education in that category), small businesses, and other for-profit organizations that are not small businesses. Government entities at multiple levels may apply, including state governments, U.S. territories or possessions, city or township governments, county governments, special district governments, and independent school districts, as well as public housing authorities and Indian housing authorities. The FOA also explicitly includes federally recognized tribal governments, other tribal governments, and tribally designated organizations. In addition, foreign (non-U.S.) institutions are eligible, and eligible federal agencies may apply. Faith-based and community-based organizations are also listed as eligible, reflecting NIH's willingness to consider a wide range of applicants where the scientific environment and project plan are strong.
Administratively, this is a discretionary grant opportunity in the health research category, listed under CFDA 93.838 (Lung Diseases Research). There is no cost sharing or matching requirement, which generally means applicants are not required to provide non-federal funds to secure the award. The opportunity was posted on January 17, 2007, and it used multiple receipt dates rather than a single deadline, with applicants directed to the full announcement for the specific submission schedule. The archive date is December 6, 2009, which indicates the FOA is no longer active in its original form, but it remains useful as a reference point for the kinds of projects NIH has sought to fund in HP research.
For full details and official instructions, the announcement provides an NIH link (http://grants.nih.gov/grants/guide/pa-files/PA-07-300.html). For access or technical issues related to the posting, the contact listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
What is the NIH funding opportunity PA-07-300 about?
PA-07-300, titled "Hypersensitivity Pneumonitis - Early Identification and Mechanisms of Disease (R01)," supports research focused on improving early recognition of hypersensitivity pneumonitis (HP) and understanding the immune-driven mechanisms that initiate and drive HP over time.
What is the main goal of this funding opportunity?
The core goal is to move the field beyond late-stage detection of HP and toward earlier diagnosis, clearer disease classification, and a more complete understanding of immune mechanisms involved in HP cause and pathogenesis.
What kinds of research questions does this FOA emphasize?
The opportunity emphasizes studies that help clarify what triggers HP in different settings, how immune responses evolve over time, and what biological signals could identify disease earlier, when interventions may be more effective.
What grant mechanism does this announcement use?
This announcement uses the NIH R01 grant mechanism, which is NIH's standard full-scale research project format designed to support hypothesis-driven, investigator-initiated research.
Is the FOA limited to one specific study design or project type?
No. The FOA indicates that R01 funding can support a range of project types, including pilot and feasibility efforts, small and self-contained projects, and work that develops or refines research technologies relevant to HP.
What types of projects are considered a fit under this FOA?
Based on the description, potential fits include foundational mechanistic immunology studies, translational studies connecting exposures to biological responses, and method or tool development that helps researchers study HP more accurately and efficiently.
Who is eligible to apply?
Eligibility is broad and includes many kinds of domestic and international organizations, spanning higher education, nonprofit, for-profit, government, tribal, and other eligible entities described in the announcement summary.
Are public or state-controlled institutions of higher education eligible?
Yes. Public or state-controlled institutions of higher education are explicitly listed as eligible applicants.
Are private institutions of higher education eligible?
Yes. Private institutions of higher education are explicitly listed as eligible applicants.
Are nonprofit organizations eligible?
Yes. Nonprofits with or without 501(c)(3) status are listed as eligible (as long as they are not institutions of higher education in that category).
Are small businesses eligible?
Yes. Small businesses are included among the eligible applicant types.
Are other for-profit organizations eligible?
Yes. Other for-profit organizations that are not small businesses are also included as eligible applicants.
Are state governments eligible to apply?
Yes. State governments are listed as eligible applicants.
Are U.S. territories or possessions eligible to apply?
Yes. U.S. territories or possessions are listed as eligible applicants.
Are local governments (city, township, county) eligible?
Yes. City or township governments and county governments are explicitly included.
Are special district governments eligible?
Yes. Special district governments are listed as eligible applicants.
Are independent school districts eligible?
Yes. Independent school districts are listed as eligible applicants.
Are public housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities are included as eligible applicants.
Are federally recognized tribal governments eligible?
Yes. Federally recognized tribal governments are explicitly included.
Are other (non-federally recognized) tribal governments eligible?
Yes. Other tribal governments are listed as eligible applicants.
Are tribally designated organizations eligible?
Yes. Tribally designated organizations are explicitly included.
Are foreign (non-U.S.) institutions eligible to apply?
Yes. The FOA explicitly states that foreign (non-U.S.) institutions are eligible.
Are federal agencies eligible to apply?
Yes. The summary notes that eligible federal agencies may apply.
Are faith-based and community-based organizations eligible?
Yes. Faith-based and community-based organizations are listed as eligible applicants.
What is the assistance listing / CFDA number for this opportunity?
The opportunity is listed under CFDA 93.838, Lung Diseases Research.
What type of grant is this (administratively)?
It is described as a discretionary grant opportunity in the health research category.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement, meaning applicants are generally not required to provide non-federal funds to secure the award.
When was this opportunity posted?
The opportunity was posted on January 17, 2007.
Is there a single application deadline?
No. The FOA used multiple receipt dates rather than a single deadline, and applicants were directed to the full announcement for the specific submission schedule.
Is PA-07-300 still active?
The archive date is December 6, 2009, indicating the FOA is no longer active in its original form. It may still be useful as a reference for the types of HP projects NIH has sought to fund.
Where can applicants find the full official announcement and instructions?
The FOA provides an NIH link for full details: http://grants.nih.gov/grants/guide/pa-files/PA-07-300.html
Who should be contacted for access or technical issues related to the posting?
For access or technical issues related to the posting, the contact listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
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