Opportunity Information: Apply for PAR 07 456

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NINDS Diversity Research Education Grants in Neuroscience (R25)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.
  • This funding opportunity was created on Dec 5, 2008 and posted on Sep 25, 2007.
  • Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: For profit organizations other than small businesses Native American tribal governments (Federally recognized) City or township governments Public housing authorities/Indian housing authorities Private institutions of higher education State governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Independent school districts County governments Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Foreign institutions are not eligible to apply.
Apply for PAR 07 456

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Opportunity Summary:

The NINDS Diversity Research Education Grants in Neuroscience (R25) program (Funding Opportunity Number PAR-07-456) is a National Institutes of Health grant opportunity designed to build and strengthen the pipeline of neuroscience researchers through structured research education programs. It uses the R25 research education mechanism, which is intended to support creative, specialized, and often programmatic educational experiences rather than standard research projects. In practice, this means an applicant organization proposes an organized set of educational and career-development activities that help participants gain the skills, knowledge, mentoring, and research exposure needed to move toward productive careers in neuroscience and related neurological research areas.

A central purpose of this opportunity is to expand and improve the diversity of the neuroscience research workforce aligned with the mission of the National Institute on Neurological Disorders and Stroke (NINDS). The announcement emphasizes recruiting and developing scientists from groups that are underrepresented in biomedical research, including individuals from underrepresented racial and ethnic groups, individuals with disabilities, and individuals from disadvantaged backgrounds. The intent is not only to increase participation, but to broaden access to high-quality training and career development so that the field benefits from the strongest possible talent pool drawn from all communities. The program refers to the intended participants as diversity research scientists or diversity trainees.

The scientific and educational scope is explicitly broad and cross-disciplinary. Proposed programs are encouraged to prepare trainees to integrate across major domains of neuroscience, including basic, translational, behavioral, prevention, clinical, and treatment research. This framing supports training models that connect laboratory discovery to clinical applications, incorporate behavioral and population perspectives, and provide exposure to the full continuum from mechanistic science through interventions and outcomes. The R25 mechanism is described as flexible, which generally signals that NINDS is open to a range of educational designs as long as they are innovative, well-structured, and clearly focused on developing participants into competitive neuroscience researchers.

This funding opportunity falls under the Health funding activity category and is associated with CFDA 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders). The opportunity is listed as discretionary and uses the grant funding instrument. No cost sharing or matching is required, reducing financial barriers for institutions that want to build or scale research education programs.

Eligibility is broad across many types of US-based organizations. Eligible applicants include public and private institutions of higher education (including public/state-controlled institutions), nonprofits (including those with 501(c)(3) status and certain nonprofits without it), for-profit organizations (including small businesses, with the exception that it specifies for-profits other than small businesses are eligible as well, alongside small businesses), and multiple levels of government entities such as state governments, county governments, city or township governments, special district governments, and independent school districts. Certain tribal entities and tribal governments are also included, as are public housing authorities/Indian housing authorities. A key restriction is that foreign institutions are not eligible to apply, meaning the applicant organization must be domestic even if the program itself includes collaborations or broader engagement consistent with NIH policy.

Administratively, the opportunity was posted September 25, 2007, with a creation date of December 5, 2008, and it used multiple receipt dates rather than a single deadline, directing applicants to the full announcement for the specific submission cycles. The archived date is October 26, 2010, which indicates this particular announcement is no longer active in its original form, though similar R25 diversity-focused research education opportunities may exist under newer announcements.

Finally, the announcement is careful to clarify what this mechanism is not meant to do. It states that the R25 support should not be used as a substitute for the NIH Ruth L. Kirschstein National Research Service Award (NRSA) training and fellowship mechanisms (such as T and F series awards) or their associated policies. In other words, the R25 is intended to support structured research education programming and pipeline development, not to replace traditional stipend-supported training slots or individual fellowships governed by NRSA rules. For full details, the official NIH posting is linked through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PAR-07-456.html, and the NIH Office of Extramural Research (OER) webmaster contacts are provided for technical access issues.

FAQs: NINDS Diversity Research Education Grants in Neuroscience (R25) - PAR-07-456

What is the NINDS Diversity Research Education Grants in Neuroscience (R25) program?

It is a National Institutes of Health (NIH) grant opportunity from the National Institute on Neurological Disorders and Stroke (NINDS) designed to build and strengthen the pipeline of neuroscience researchers through structured research education programs. The program uses the R25 research education mechanism, which supports organized educational and career-development experiences rather than standard research projects.

What is the funding opportunity number?

The Funding Opportunity Number is PAR-07-456.

What does the R25 mechanism support?

The R25 mechanism is intended to support creative, specialized, and often programmatic educational experiences. In practice, an applicant organization proposes a structured set of education and career-development activities that provide participants with skills, knowledge, mentoring, and research exposure to help them progress toward productive careers in neuroscience and related neurological research areas.

Is this grant meant to fund a traditional research project?

No. The R25 mechanism is framed as supporting research education programming (organized educational and career-development activities) rather than funding a standard research project.

What is the central purpose of this opportunity?

A central purpose is to expand and improve the diversity of the neuroscience research workforce aligned with the NINDS mission by recruiting and developing scientists from groups that are underrepresented in biomedical research.

Who are the intended participants?

The announcement refers to intended participants as diversity research scientists or diversity trainees. The program focuses on recruiting and developing individuals from underrepresented groups in biomedical research, including individuals from underrepresented racial and ethnic groups, individuals with disabilities, and individuals from disadvantaged backgrounds.

Does the program focus only on increasing participation, or also on training quality?

It is intended to do both: increase participation and broaden access to high-quality training and career development so the neuroscience field benefits from the strongest possible talent pool drawn from all communities.

How broad is the scientific and educational scope?

The scope is explicitly broad and cross-disciplinary. Programs are encouraged to prepare trainees to integrate across major domains of neuroscience, including basic, translational, behavioral, prevention, clinical, and treatment research.

What types of training models does NINDS appear to encourage under this R25?

Based on the description, NINDS is open to training models that connect laboratory discovery to clinical applications, incorporate behavioral and population perspectives, and provide exposure across the continuum from mechanistic science through interventions and outcomes. The R25 is described as flexible, suggesting openness to a range of innovative, well-structured educational designs focused on developing competitive neuroscience researchers.

What is the funding activity category and CFDA number?

The opportunity falls under the Health funding activity category and is associated with CFDA 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders).

What type of award instrument is used?

It is a discretionary opportunity using the grant funding instrument.

Is cost sharing or matching required?

No. The opportunity states that no cost sharing or matching is required.

What organizations are eligible to apply?

Eligibility is broad across many types of US-based organizations. Eligible applicants include:

  • Public and private institutions of higher education (including public/state-controlled institutions)
  • Nonprofits (including those with 501(c)(3) status and certain nonprofits without it)
  • For-profit organizations (including small businesses, and for-profits other than small businesses)
  • Government entities (state governments, county governments, city or township governments, special district governments, and independent school districts)
  • Certain tribal entities and tribal governments
  • Public housing authorities/Indian housing authorities

Are foreign institutions eligible to apply?

No. A key restriction is that foreign institutions are not eligible to apply, meaning the applicant organization must be domestic.

Does the announcement mention anything about deadlines?

Yes. It used multiple receipt dates rather than a single deadline, and applicants were directed to the full announcement for specific submission cycles.

When was this opportunity posted and when was it archived?

The opportunity was posted on September 25, 2007. The archived date is October 26, 2010.

Is this specific funding announcement still active?

The archived date (October 26, 2010) indicates this particular announcement is no longer active in its original form, though similar R25 diversity-focused research education opportunities may exist under newer announcements.

What is the creation date listed for the opportunity?

The creation date is listed as December 5, 2008.

What is this R25 opportunity not intended to replace?

The announcement clarifies that R25 support should not be used as a substitute for the NIH Ruth L. Kirschstein National Research Service Award (NRSA) training and fellowship mechanisms (such as T and F series awards) or their associated policies.

Where can applicants find the official NIH posting?

The official NIH posting is available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAR-07-456.html

Who should be contacted for technical access issues?

The announcement indicates that NIH Office of Extramural Research (OER) webmaster contacts are provided for technical access issues.

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