Opportunity Information: Apply for CDC RFA PS04 230
Apply for CDC RFA PS04 230
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Promoting Extensive Implementation of Quality Prevention of Mother to Child Transmission (PMTCT) Activities in the Republic of Uganda" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067 Global AIDS.
- This funding opportunity was created on Mar 2, 2010 and posted on Mar 2, 2010.
- Applicants must submit their applications by Apr 30, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,506,534.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- Protecting Families Against AIDS (PREFA) is a local indigenous non government organization in Uganda. It received a CDC Cooperative Agreement to provide service delivery for the Prevention of Mother to Child HIV Transmission. PREFA has worked closely with the district health teams of 36 districts to support their administrative, programmatic and fiduciary management of individual district subgrants to implement PMTCT services in accordance with approved district workplans. A gap between this award and the follow on award for 6 months would have two principal adverse programmatic impacts. First, approximately 240,000 pregnant women would not receive PMTCT services. As a result of this, at least 8,000 HIV infected pregnant women would not be identified and therefore not be provided indicated prevention, care and treatment services. Also, approximately 1,200 new HIV infections among infants would not be prevented many of these infections will result in death. Secondly, PEPFAR s efforts to strengthen health systems and foster host government ownership of HIV activities would be seriously impacted. District and health facility supply chain, information, human resources (hiring, training, mentoring), governance and financing systems would be disrupted also, because of the instability in funding, the commitment to continue increasing host government ownership of these activities and partnering with CDC to do so will be adversely affected. PREFA is the only organization which can continue to carry out these activities until the new FOA is awarded, as it is the only organization which has supported these districts to provide PMTCT services and strengthen their health systems since 2004. Further, PREFA owns the protocol for the PHE study and a new recipient would be required to start from the scratch on the study. A new award to cover this gap cannot be made in time, and a new awardee would need up to 6 months to establish the minimum district based program implementation and accountability systems which PREFA has put in place.
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Opportunity Summary:
The Centers for Disease Control and Prevention (CDC) funding opportunity CDC RFA PS04-230, titled "Promoting Extensive Implementation of Quality Prevention of Mother to Child Transmission (PMTCT) Activities in the Republic of Uganda," is a discretionary cooperative agreement focused on expanding and maintaining high-quality PMTCT services across Uganda. The purpose mirrors the original announcement published July 23, 2004: to broaden national PMTCT coverage, deliver PMTCT training, identify weaknesses in the existing national PMTCT program, develop practical strategies to close those gaps, and carry out broader PMTCT promotion, policy support, and quality assurance work. In plain terms, the grant is designed to help Uganda reach more pregnant women with proven HIV prevention services, improve the consistency and quality of those services, and strengthen the systems that keep them running.
The program described in the notice is organized around two major components. The first is direct PMTCT program support and service delivery assistance across 36 districts in Uganda. This district-focused work was intended to continue through September 30, 2010, or until a new award is made under the later competitive funding opportunity announcement (FOA) PS10-1021, whichever happened first. The second component is a longer-running public health evaluation effort, the Tororo Child Cohort study, categorized here as a Public Health Evaluation (PHE) study, planned to continue through September 30, 2013. Together, these components combine immediate service delivery support with longer-term learning and evaluation, so implementation and evidence-building move forward at the same time.
A key element of this specific opportunity is continuity. The eligibility language explains that Protecting Families Against AIDS (PREFA), a local indigenous nongovernmental organization in Uganda, had already been operating the CDC cooperative agreement and working closely with district health teams in all 36 districts since 2004. PREFA’s role included supporting administrative, programmatic, and fiduciary management for district subgrants so that districts could implement PMTCT services aligned with approved district workplans. The notice stresses that a funding gap of about six months between the current award and the follow-on award would cause major harm. On the service side, the estimate provided is that roughly 240,000 pregnant women would miss PMTCT services during that interruption, with at least 8,000 HIV-positive pregnant women not identified and therefore not linked to appropriate prevention, care, and treatment services. The projected downstream impact includes about 1,200 infant HIV infections that would not be prevented, with the added warning that many of those infections could result in death.
Beyond the immediate health consequences, the announcement highlights broader health system risks tied to PEPFAR goals, particularly strengthening country systems and increasing host-government ownership of HIV activities. It argues that disrupted funding would destabilize district and health facility systems that PMTCT depends on, including supply chains, health information systems, human resources processes (hiring, training, mentoring), governance, and financing. The practical message is that even short interruptions can unravel the operating routines and accountability structures that keep services functioning, and they can weaken trust and momentum in government-led ownership efforts.
The eligibility justification also explains why PREFA is positioned as uniquely able to carry the work through the interim period. According to the notice, PREFA is the only organization with the established district-based implementation and accountability systems needed to continue service delivery without a ramp-up period, and it has been embedded in these districts for years. It further notes that PREFA owns the protocol for the Tororo Child Cohort PHE study, meaning that changing recipients would not be a simple handoff; a new organization would effectively have to restart major elements of the study. The CDC also states that a new awardee would likely need up to six months just to put in place the minimum management and accountability systems that PREFA already has, which reinforces the argument for continuity during the transition to the next competitive award.
From an administrative standpoint, the opportunity is listed as a cooperative agreement, which typically means substantial involvement by the CDC in collaboration, oversight, and technical direction compared to a standard grant. The posting date and creation date are both March 2, 2010, with an application closing date of April 30, 2010, and an archive date of May 30, 2010. The opportunity anticipated a single award (ExpectedAwards: 1) under CFDA 93.067 (Global AIDS), with an estimated total funding amount of $2,506,534. There is no cost-sharing or matching requirement indicated. Award ceiling and floor are both listed as 0, which often reflects that the specific ceiling/floor is not stated in that data field rather than implying no funding.
For applicants or stakeholders seeking clarification, the contact information provided points to CDC’s procurement and grants office support (PGO TIMS grants) at 770-488-2700, with a general email referenced for assistance accessing the full announcement electronically.
Frequently Asked Questions (FAQs)
What is CDC RFA PS04-230?
CDC RFA PS04-230 is a CDC discretionary cooperative agreement titled "Promoting Extensive Implementation of Quality Prevention of Mother to Child Transmission (PMTCT) Activities in the Republic of Uganda." It is focused on expanding and maintaining high-quality PMTCT services across Uganda while also supporting evaluation activities that generate evidence to strengthen programming.
What is the main purpose of this funding opportunity?
The purpose is to broaden national PMTCT coverage in Uganda, deliver PMTCT training, identify weaknesses in the national PMTCT program, develop practical strategies to address gaps, and support broader PMTCT promotion, policy support, and quality assurance. In practical terms, it is designed to help reach more pregnant women with proven HIV prevention services, improve consistency and quality, and strengthen the systems that keep services operating.
What does PMTCT mean in this opportunity?
PMTCT refers to Prevention of Mother to Child Transmission of HIV. The opportunity is centered on ensuring pregnant women can access services that reduce HIV transmission to infants and connect HIV-positive pregnant women to prevention, care, and treatment services.
What type of award is this?
This opportunity is a cooperative agreement. That typically indicates substantial CDC involvement in collaboration, oversight, and technical direction compared with a standard grant.
How is the program organized?
The notice describes two major components: (1) direct PMTCT program support and service delivery assistance across 36 districts in Uganda, and (2) a longer-running public health evaluation effort called the Tororo Child Cohort study (categorized as a Public Health Evaluation, or PHE, study).
What is included in the direct PMTCT program support component?
The first component focuses on district-based implementation and assistance for PMTCT service delivery across 36 districts. It is described as district-focused work supporting the continuation and quality of PMTCT services in alignment with approved district workplans.
What is the Tororo Child Cohort study in this notice?
The Tororo Child Cohort study is identified as a Public Health Evaluation (PHE) study included in the opportunity as the second component. It is intended to continue beyond the service delivery support period to generate longer-term learning and evaluation that can inform PMTCT programming.
How long was the district-focused PMTCT support intended to continue?
According to the notice, the district-focused PMTCT program support was intended to continue through September 30, 2010, or until a new award is made under the later competitive funding opportunity announcement (FOA) PS10-1021, whichever occurred first.
How long was the Tororo Child Cohort PHE study intended to continue?
The notice states the Tororo Child Cohort PHE study was planned to continue through September 30, 2013.
Why does the notice emphasize continuity of funding and operations?
The notice argues that a funding gap of about six months between the current award and the follow-on award would cause major harm to service delivery and to broader health system functioning. It highlights both immediate health impacts (missed services and preventable infant infections) and system impacts (destabilization of routines and accountability structures that keep PMTCT services running).
What service disruption impacts are described if there is a six-month funding gap?
The notice estimates that approximately 240,000 pregnant women would miss PMTCT services during a six-month interruption. It also estimates at least 8,000 HIV-positive pregnant women would not be identified and therefore would not be linked to appropriate prevention, care, and treatment services.
What infant health impacts are projected if services are interrupted?
The notice projects that about 1,200 infant HIV infections would not be prevented during the interruption period, with a warning that many of those infections could result in death.
What broader health system risks are mentioned in the notice?
The announcement ties the risks to PEPFAR goals, including strengthening country systems and increasing host-government ownership of HIV activities. It states disrupted funding could destabilize key systems PMTCT depends on, including supply chains, health information systems, human resources processes (hiring, training, mentoring), governance, and financing.
Which organization is identified in the eligibility justification?
The notice identifies Protecting Families Against AIDS (PREFA), a local indigenous nongovernmental organization in Uganda, as the organization that had already been operating the CDC cooperative agreement and working with district health teams in all 36 districts since 2004.
What role did PREFA play according to the notice?
PREFA’s role included supporting administrative, programmatic, and fiduciary management for district subgrants so districts could implement PMTCT services aligned with approved district workplans, in close collaboration with district health teams.
Why does the notice state PREFA is uniquely positioned for this interim period?
The notice states PREFA is the only organization with the established district-based implementation and accountability systems needed to continue service delivery without a ramp-up period. It also states that a new awardee would likely need up to six months to put in place minimum management and accountability systems that PREFA already has.
How does the Tororo Child Cohort study affect continuity considerations?
The notice states PREFA owns the protocol for the Tororo Child Cohort PHE study, and that changing recipients would not be a simple handoff. It suggests a new organization would effectively have to restart major elements of the study.
How many awards were expected under this opportunity?
The opportunity anticipated a single award (ExpectedAwards: 1).
What is the estimated total funding amount?
The estimated total funding amount listed is $2,506,534.
What CFDA number is associated with this opportunity?
The opportunity is listed under CFDA 93.067, described as Global AIDS.
Is cost sharing or matching required?
No cost-sharing or matching requirement is indicated in the information provided.
Why do the award ceiling and award floor show as 0?
The award ceiling and floor are both listed as 0 in the opportunity data. This often reflects that a specific ceiling or floor is not stated in that field rather than implying there is no funding, especially since an estimated total funding amount is provided.
What are the key dates for this opportunity?
The posting date and creation date are both March 2, 2010. The application closing date is April 30, 2010. The archive date is May 30, 2010.
What is FOA PS10-1021 and how is it related?
FOA PS10-1021 is described as a later competitive funding opportunity announcement referenced in the notice. The district-focused work under this opportunity was intended to continue until September 30, 2010, or until a new award is made under PS10-1021, whichever occurred first.
Who can be contacted for help or clarification based on the notice?
The contact information provided points to CDC’s procurement and grants office support (PGO TIMS grants) at 770-488-2700, and references a general email for assistance accessing the full announcement electronically.
What geographic area does the funded work focus on?
The program support and service delivery assistance described in the notice is focused on 36 districts in the Republic of Uganda.
What is the relationship between service delivery and evaluation in this opportunity?
The notice frames the opportunity as combining immediate service delivery support (district PMTCT assistance) with longer-term learning and evaluation (the Tororo Child Cohort PHE study), so implementation and evidence-building proceed at the same time.
What kinds of system functions are explicitly mentioned as being at risk during disruption?
The notice explicitly mentions supply chains, health information systems, human resources processes (hiring, training, mentoring), governance, and financing as systems that could be destabilized by interrupted funding.
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