Research on Mild and/or Unilateral Hearing Loss (R01) | Apply Online

Opportunity Summary:

The Research on Mild and/or Unilateral Hearing Loss (R01) opportunity (Funding Opportunity Number PA 07 038) is a National Institutes of Health (NIH) discretionary grant announcement that supports health-related research aimed at improving what is known about mild hearing loss and unilateral (one-sided) hearing loss in infants and young children. The central idea behind the announcement is that these forms of hearing loss are frequently underestimated or missed altogether, yet they can still have real consequences for a child s development. The FOA emphasizes that even milder thresholds, such as hearing loss below about 40 dB HL in one or both ears, or any level of hearing loss in just one ear, can contribute to difficulties with speech and language development, behavior, academic performance, and broader developmental outcomes. Because of that, the program is looking for well designed studies that treat mild and unilateral hearing loss as meaningful clinical and public health issues rather than minor findings.

The scientific scope is intentionally broad, inviting projects that can deepen understanding and produce practical improvements in three major areas: prevention, diagnosis, and treatment. On prevention, applicants might investigate risk factors, early life exposures, or healthcare and screening practices that could reduce the incidence or severity of mild or unilateral loss. On diagnosis, the FOA highlights the need for better ways to identify these cases earlier and more accurately, which can include improved screening approaches, refined audiologic assessment methods, or new tools that capture functional listening problems that standard measures may overlook. On treatment, the announcement supports research into interventions that could improve outcomes for children with mild or unilateral hearing loss, including clinical management strategies, amplification or assistive technologies, habilitation approaches, or other services that address downstream effects on communication and learning. Overall, the purpose is not only to document that problems exist, but to generate evidence that can change practice by helping clinicians and systems detect these children earlier and support them more effectively.

This FOA uses the NIH R01 mechanism, meaning it is intended for more mature, hypothesis driven, and substantial projects that can be carried out over a multi year period with a scope and budget appropriate to the work. The announcement notes that award size and project duration are expected to vary depending on what is proposed, and that the total dollars and number of awards will ultimately depend on the quality, cost, and length of the applications NIH receives. It also runs in parallel with an announcement of identical scientific scope that uses the R21 mechanism (PA 07 037), which typically fits smaller, earlier stage, or higher risk exploratory projects, while the R01 track is better suited for full scale studies with stronger preliminary justification.

Eligibility is wide and includes many types of domestic organizations such as public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non 501(c)(3) entities), small businesses, for profit organizations (including those other than small businesses), state and local governments (including county and city or township governments), independent school districts, special district governments, public housing authorities and Indian housing authorities, and Native American tribal governments and organizations. The announcement also specifies that foreign institutions may apply, that eligible federal agencies may apply, and that faith based or community based organizations are not excluded. Cost sharing or matching is not required, which generally lowers barriers for applicants who may not have access to non federal matching funds.

From an administrative standpoint, the opportunity is categorized under the health funding activity area and is associated with CFDA 93.173 (Research Related to Deafness and Communication Disorders) and 93.283 (Centers for Disease Control and Prevention Investigations and Technical Assistance), as listed in the source data. The original posting date is November 21, 2006, with multiple receipt dates for applications referenced in the full announcement rather than a single fixed deadline. The listing indicates an archive date of December 6, 2009, meaning it was active in that period and applicants would have needed to follow the linked NIH guide notice for the specific receipt dates and submission instructions in effect at the time.

For applicants needing the complete requirements, submission instructions, and receipt date schedule, the FOA points to the full NIH announcement page at http://grants.nih.gov/grants/guide/pa-files/PA-07-038.html and provides contact support through the NIH Office of Extramural Research (OER) webmaster email for access or linking problems.

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