Opportunity Information: Apply for PAR 09 254
Apply for PAR 09 254
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Specialized Programs of Translational Research in Acute Stroke (SPOTRIAS) for Year 2009 (P50)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.
- This funding opportunity was created on Aug 14, 2009 and posted on Aug 14, 2009.
- Applicants must submit their applications by Oct 1, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: County governments Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Private institutions of higher education For profit organizations other than small businesses State governments City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Specialized Programs of Translational Research in Acute Stroke (SPOTRIAS) for Year 2009 (P50) is a National Institutes of Health opportunity administered through the National Institute of Neurological Disorders and Stroke (NINDS). Its central aim is to accelerate practical, patient-focused advances in acute stroke care by funding organized, multidisciplinary teams that can move promising ideas more quickly from research settings into real clinical workflows. The program is built around the idea that meaningful improvements in early stroke diagnosis and treatment are most likely to come from coordinated collaboration across specialties rather than from isolated projects. By supporting integrated translational research efforts, SPOTRIAS is intended to help reduce stroke-related disability and death through faster diagnosis and more effective interventions during the acute window when treatment decisions have the greatest impact.
This opportunity uses the P50 Specialized Center grant mechanism, which is designed for large, structured programs that combine multiple interrelated research activities under a single umbrella with shared leadership and common goals. In practice, a P50 center structure supports a coordinated program rather than a single standalone study, encouraging investigators to align projects, share resources, and build clinical research capacity that can consistently produce actionable advances in acute stroke management. NINDS explicitly invited both new applications and renewal applications, signaling continued investment in established centers while also leaving space for new institutions or teams with strong translational concepts and the ability to build a cohesive program.
Funding levels and the number of awards were not fixed in the announcement because SPOTRIAS applications can differ widely in size, scope, and complexity. Instead, NINDS indicated that award size and duration would vary depending on what each application proposed, and that the total amount funded and the number of funded centers would depend on factors such as the quality of the applications, the requested budgets, and the proposed project periods. The announcement also states there is no cost sharing or matching requirement, which reduces barriers for applicants that might otherwise have difficulty providing institutional matching funds.
Eligibility for SPOTRIAS was broad and included many types of organizations that can support serious clinical and translational research programs. Eligible applicants listed in the notice include public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits), for-profit organizations (other than small businesses), and multiple levels of government such as state, county, city or township governments, special district governments, and independent school districts. The eligibility language also extended to various mission-driven and community-anchored entities, including faith-based or community-based organizations, and to institutions serving specific populations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and Tribally Controlled Colleges and Universities (TCCUs). The notice further allowed certain tribal governments and tribal organizations, U.S. territories or possessions, regional organizations, eligible federal agencies, and even non-U.S. (foreign) organizations, reflecting an intent to attract strong translational stroke programs wherever the necessary expertise and clinical infrastructure exist.
Administratively, the funding opportunity is identified as PAR-09-254 and is categorized as a discretionary grant in the health funding area under CFDA 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders). It was posted and created on August 14, 2009, with an original and current closing date of October 1, 2009, and an archive date of November 1, 2009. The full announcement was hosted through the NIH grants guide (linked in the notice), and NIH provided contact instructions through the Office of Extramural Research (OER) for applicants who had trouble accessing or linking to the official posting.
In summary, SPOTRIAS (PAR-09-254) was designed to fund specialized, collaborative translational research centers focused specifically on acute stroke, with the practical goal of speeding up diagnosis and improving early treatment so that fewer patients die or live with severe disability. The use of the P50 mechanism underscores that NINDS was looking for integrated, center-style programs capable of sustained, team-based clinical research and real-world clinical impact, rather than a collection of unrelated individual projects.
SPOTRIAS (PAR-09-254) Grant Opportunity FAQs
What is the SPOTRIAS Year 2009 (P50) funding opportunity?
SPOTRIAS stands for Specialized Programs of Translational Research in Acute Stroke. The Year 2009 opportunity (PAR-09-254) is a National Institutes of Health (NIH) program administered by the National Institute of Neurological Disorders and Stroke (NINDS) to support organized, multidisciplinary translational research centers focused on acute stroke.
What is the main purpose of SPOTRIAS?
The central goal is to speed up practical, patient-focused advances in acute stroke care by helping teams move promising ideas from research settings into real clinical workflows more quickly. The program emphasizes reducing stroke-related disability and death by improving early diagnosis and treatment during the acute window when decisions matter most.
What type of research approach does SPOTRIAS emphasize?
SPOTRIAS is built around coordinated, multidisciplinary collaboration across specialties. The opportunity is intended for integrated translational research efforts rather than isolated, standalone projects, with the expectation that coordinated teams are more likely to deliver meaningful improvements in acute stroke diagnosis and treatment.
Which agency administers this opportunity?
This is an NIH opportunity administered through NINDS (National Institute of Neurological Disorders and Stroke).
What funding mechanism is used for SPOTRIAS?
SPOTRIAS uses the P50 Specialized Center grant mechanism. This mechanism is designed for large, structured programs that combine multiple interrelated research activities under a single umbrella, with shared leadership, shared resources, and common goals.
Does this opportunity support a single project or a center-style program?
It is intended to support a center-style program. The P50 structure encourages investigators to align multiple related activities, share resources, and build clinical research capacity aimed at producing actionable advances in acute stroke management.
Are both new and renewal applications allowed?
Yes. NINDS explicitly invited both new applications and renewal applications, reflecting continued investment in established centers while still leaving room for new institutions or teams with strong translational concepts.
How much funding is available per award?
The announcement did not set a fixed award amount. SPOTRIAS applications can vary widely in size, scope, and complexity, so NINDS indicated that award size would vary depending on what each application proposes.
How long can the project period be?
The announcement states that award duration would vary based on the proposed project periods in applications. No single standard duration is specified in the provided notice summary.
How many awards will be made?
The number of funded centers was not fixed. NINDS indicated it would depend on factors such as the quality of applications, requested budgets, and proposed project periods.
Is cost sharing or matching required?
No. The announcement states there is no cost sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad. The notice lists many eligible applicant types, including public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits), for-profit organizations (other than small businesses), and multiple levels of government (state, county, city or township, special district governments, and independent school districts).
Are community-based or faith-based organizations eligible?
Yes. The eligibility language explicitly extends to faith-based and community-based organizations.
Are minority-serving institutions eligible?
Yes. The notice includes institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and Tribally Controlled Colleges and Universities (TCCUs).
Are tribal entities eligible?
Yes. The notice allows certain tribal governments and tribal organizations.
Are U.S. territories or possessions eligible?
Yes. The eligibility language includes U.S. territories or possessions.
Are non-U.S. (foreign) organizations eligible?
Yes. The notice states that non-U.S. (foreign) organizations are eligible.
Are federal agencies eligible to apply?
Yes. The eligibility language includes eligible federal agencies.
What is the CFDA number and funding area associated with this opportunity?
The opportunity is listed under CFDA 93.853, titled Extramural Research Programs in the Neurosciences and Neurological Disorders, and it is categorized in the health funding area.
What is the opportunity number and how is it classified?
The funding opportunity is identified as PAR-09-254 and is categorized as a discretionary grant.
When was the opportunity posted and when did it close?
It was posted and created on August 14, 2009. The original and current closing date was October 1, 2009. The archive date was November 1, 2009.
Where was the official announcement hosted?
The full announcement was hosted through the NIH grants guide, as referenced in the notice.
What should applicants do if they have trouble accessing the official posting?
NIH provided contact instructions through the Office of Extramural Research (OER) for applicants who had trouble accessing or linking to the official posting.
What kinds of outcomes is SPOTRIAS trying to achieve?
SPOTRIAS is aimed at real-world clinical impact in acute stroke care, specifically faster diagnosis and more effective early interventions, with the practical goal of reducing stroke-related disability and death.
Why does the announcement stress team-based collaboration?
The program is based on the premise that meaningful improvements in early stroke diagnosis and treatment are more likely to come from coordinated collaboration across specialties than from isolated projects, especially when the goal is to translate research into clinical workflows.
What does the P50 structure enable that a single-project grant might not?
Based on the notice summary, the P50 structure supports a coordinated program with multiple interrelated activities, shared leadership, and shared resources. It encourages alignment across projects and builds clinical research capacity designed to consistently produce actionable advances in acute stroke management.
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