Opportunity Information: Apply for RFA DA 10 001
Apply for RFA DA 10 001
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Substance Use and Abuse among U.S. Military Personnel, Veterans and their Families (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.399 Cancer Control.
- This funding opportunity was created on Jul 29, 2009 and posted on Jul 28, 2009.
- Applicants must submit their applications by Dec 22, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- Eligible applicants include: County governments State governments Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Public and State controlled institutions of higher education Small businesses Special district governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The grant opportunity titled "Substance Use and Abuse among U.S. Military Personnel, Veterans and their Families (R01)" (Funding Opportunity Number RFA-DA-10-001) is a discretionary NIH-led research funding announcement focused on improving what is known, and what can be done, about substance use and related mental health challenges affecting U.S. service members, recently separated personnel, veterans, and their families. It is jointly issued by the National Institute on Drug Abuse (NIDA), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Cancer Institute (NCI), and the U.S. Department of Veterans Affairs (VA). The central aim is to strengthen and speed up research on alcohol, tobacco, and other drug use and misuse, including both illicit substances and prescription medications, and to address the mental health problems that often co-occur with or are worsened by substance use in military-connected populations.
The scientific scope is broad but clearly anchored in three major research areas: epidemiology and etiology (understanding patterns, rates, risk factors, and causes), identification (improving detection, screening, and recognition of substance use problems and co-occurring mental health issues), and prevention and treatment (developing, testing, and improving interventions that reduce harmful use and improve outcomes). The target populations include active duty personnel as well as recently separated troops, with explicit mention of individuals connected to Iraq and Afghanistan deployments, and it also extends to family members who may be affected directly or indirectly through stress, reintegration challenges, trauma exposure, or caregiving burdens. A notable emphasis is placed on the intersection of substance use/abuse and mental health, reflecting the reality that conditions like PTSD, depression, anxiety, and related issues frequently overlap with alcohol and drug misuse in these groups.
Within that overall mission, the VA highlights a specific priority: research that advances prevention and treatment of mental health conditions that are comorbid with substance use/abuse among veterans of Iraq and Afghanistan deployments, including National Guard and Reservists, as well as their families. This signals strong interest in practical, clinically relevant work that can improve care delivery and outcomes for post-9/11 era veterans and family systems, particularly where substance use and mental health challenges interact and complicate recovery.
From a funding and structure standpoint, this announcement uses the R01 grant mechanism, which is typically intended for more mature, hypothesis-driven projects that can support larger-scale studies than exploratory mechanisms. It also runs in parallel with a companion announcement of identical scientific scope that uses the R21 mechanism (RFA-DA-10-002), generally associated with earlier-stage or exploratory research. For Fiscal Year 2010, the participating organizations planned to commit approximately $7.0 million in total costs across both the R01 and the parallel R21 announcements, with an expected 11 to 21 total new awards across the two FOAs. The stated FY2010 contributions were approximately $2.0 million from NIDA, $2.0 million from NIAAA, and $1.0 million from NCI, with the VA Clinical Science Research and Development Service (CSRD) estimating up to $2.0 million toward this R01 announcement specifically. The VA indicated it encouraged applicants to the R21 FOA but would not participate in funding the R21 proposals, underscoring that VA financial participation was tied to the R01 track for this initiative.
Key administrative details include a posted date of July 28, 2009, with an original and current closing date of December 22, 2009, and an archive date of January 22, 2010, meaning this particular announcement is historical rather than currently open. The award ceiling is listed as $500,000. There is no cost sharing or matching requirement, which generally lowers barriers for applicants who might otherwise need to secure non-federal funds to complement the award. The funding activity categories are listed under education and health, and the CFDA numbers include 93.273 (Alcohol Research Programs), 93.279 (Drug Abuse and Addiction Research Programs), and 93.399 (Cancer Control), reflecting the involvement of NIAAA, NIDA, and NCI and the inclusion of tobacco-related research as a cancer control priority.
Eligibility is intentionally broad and includes many types of organizations capable of conducting health research, such as state, county, city/township, and special district governments; public and private institutions of higher education; nonprofit organizations (both with and without 501(c)(3) status, aside from higher education); for-profit organizations (including small businesses and other for-profits); independent school districts; public housing authorities/Indian housing authorities; and Native American tribal governments and tribal organizations. Additional eligible applicants explicitly include Alaska Native and Native Hawaiian Serving Institutions, Hispanic-Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based and community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and even non-U.S. entities (foreign organizations). Taken together, this eligibility language suggests the funders were seeking to draw ideas and capacity from a wide range of research and community contexts, including those with direct ties to military communities, veteran populations, and underserved groups.
The full announcement was hosted through the NIH grants system, with an additional information link provided through the NIH Guide for Grants and Contracts, and contacts routed through the NIH Office of Extramural Research (OER) webmaster for access and linking issues. Overall, the opportunity was designed to produce actionable knowledge and interventions that address substance use, misuse, and addiction, alongside related mental health problems, in military and veteran populations and within the family environments that shape and are shaped by these conditions.
Frequently Asked Questions (FAQs)
What is the name and funding opportunity number for this grant?
The opportunity is titled "Substance Use and Abuse among U.S. Military Personnel, Veterans and their Families (R01)" and the Funding Opportunity Number is RFA-DA-10-001.
Who issued this funding announcement?
This is an NIH-led research funding announcement jointly issued by the National Institute on Drug Abuse (NIDA), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Cancer Institute (NCI), and the U.S. Department of Veterans Affairs (VA).
What is the overall purpose of this opportunity?
The central aim is to strengthen and accelerate research on alcohol, tobacco, and other drug use and misuse (including illicit drugs and prescription medications) in military-connected populations, and to address mental health problems that commonly co-occur with or are worsened by substance use.
Which populations are the focus of the research?
The target populations include active duty personnel, recently separated service members, veterans, and their family members. The announcement explicitly mentions individuals connected to Iraq and Afghanistan deployments and recognizes the role of family systems affected by stress, reintegration challenges, trauma exposure, and caregiving burdens.
What substances and topics are included in the scientific scope?
The scope includes alcohol, tobacco, and other drugs, covering misuse and abuse of illicit substances as well as prescription medications. It also includes the mental health challenges that intersect with substance use in these populations.
What major research areas does the announcement emphasize?
The scientific scope is broad but anchored in three major areas: (1) epidemiology and etiology, (2) identification, and (3) prevention and treatment.
What does "epidemiology and etiology" mean in the context of this FOA?
Within this announcement, epidemiology and etiology refers to research that improves understanding of patterns, rates, risk factors, and causes of substance use and misuse and related problems in military personnel, veterans, and families.
What does "identification" research refer to here?
Identification refers to improving detection, screening, and recognition of substance use problems and co-occurring mental health issues in military-connected populations.
What does "prevention and treatment" research include?
Prevention and treatment includes developing, testing, or improving interventions intended to reduce harmful substance use and improve outcomes, particularly when substance use co-occurs with mental health concerns.
How important is the substance use and mental health intersection in this opportunity?
It is a notable emphasis. The announcement highlights that conditions such as PTSD, depression, anxiety, and related issues frequently overlap with alcohol and drug misuse in military-connected groups, and it encourages research that reflects this reality.
Does the VA identify a specific research priority within this announcement?
Yes. The VA highlights a priority for research that advances prevention and treatment of mental health conditions comorbid with substance use/abuse among veterans of Iraq and Afghanistan deployments (including National Guard and Reservists) and their families.
What type of grant mechanism is used?
This opportunity uses the NIH R01 grant mechanism, which is typically intended for more mature, hypothesis-driven projects and can support larger-scale studies than exploratory mechanisms.
Is there a related or companion announcement?
Yes. There is a parallel companion announcement with identical scientific scope using the R21 mechanism: RFA-DA-10-002.
What is the key difference between the R01 and the companion R21 in this context?
Based on the description provided, the R01 is positioned for more mature, hypothesis-driven projects, while the R21 is generally associated with earlier-stage or exploratory research. The two announcements run in parallel and share the same scientific scope.
How much funding was planned for this initiative?
For Fiscal Year 2010, the participating organizations planned to commit approximately $7.0 million in total costs across both the R01 and the parallel R21 announcements.
How many awards were expected?
Across the two FOAs (R01 and R21), the funders expected approximately 11 to 21 total new awards.
What were the stated FY2010 funding contributions by participating organizations?
The stated contributions were approximately $2.0 million from NIDA, $2.0 million from NIAAA, and $1.0 million from NCI. The VA Clinical Science Research and Development Service (CSRD) estimated up to $2.0 million toward this R01 announcement specifically.
Does the VA fund the companion R21 announcement?
No. The VA indicated it encouraged applicants to the R21 FOA but would not participate in funding the R21 proposals. VA financial participation was tied to the R01 track for this initiative.
Is there an award ceiling?
Yes. The award ceiling is listed as $500,000.
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement.
What are the key dates for this opportunity?
The posted date is July 28, 2009. The original and current closing date is December 22, 2009. The archive date is January 22, 2010.
Is this funding opportunity currently open?
No. Based on the closing date (December 22, 2009) and archive date (January 22, 2010), this particular announcement is historical and not currently open.
What are the funding activity categories listed for this opportunity?
The funding activity categories are listed under education and health.
Which CFDA numbers are associated with this opportunity?
The CFDA numbers listed are 93.273 (Alcohol Research Programs), 93.279 (Drug Abuse and Addiction Research Programs), and 93.399 (Cancer Control).
Why is the National Cancer Institute (NCI) involved in a substance use announcement?
Based on the information provided, NCI involvement aligns with the inclusion of tobacco-related research as a cancer control priority, reflected in CFDA 93.399 (Cancer Control).
Who is eligible to apply?
Eligibility is broad and includes state, county, city/township, and special district governments; public and private institutions of higher education; nonprofits (with and without 501(c)(3) status, other than higher education); for-profit organizations (including small businesses); independent school districts; public housing authorities/Indian housing authorities; Native American tribal governments and tribal organizations; and additional categories such as eligible federal agencies, regional organizations, U.S. territories or possessions, and foreign organizations.
Are minority-serving institutions and community organizations included in eligibility?
Yes. Eligibility explicitly includes Alaska Native and Native Hawaiian Serving Institutions, Hispanic-Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), as well as faith-based and community-based organizations.
Can non-U.S. (foreign) organizations apply?
Yes. The eligibility language explicitly includes non-U.S. entities (foreign organizations).
Where was the full announcement hosted and where could applicants look for more information?
The full announcement was hosted through the NIH grants system, with an additional information link through the NIH Guide for Grants and Contracts.
Who was listed as the contact for access or linking issues?
Contacts for access and linking issues were routed through the NIH Office of Extramural Research (OER) webmaster.
What kinds of outcomes was this opportunity designed to support?
The opportunity was designed to produce actionable knowledge and interventions addressing substance use, misuse, and addiction, alongside related mental health problems, in military and veteran populations and within the family environments that influence and are influenced by these conditions.
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| Funding Opportunity |
|---|
| Substance Use and Abuse among U.S. Military Personnel, Veterans and their Families (R21) Apply for RFA DA 10 002 Funding Number: RFA DA 10 002 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| NIMH Career Transition Award for Intramural Investigators (K22) Apply for PAR 09 246 Funding Number: PAR 09 246 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Innovations in Biomedical Computational Science and Technology Initiative (SBIR R43/R44) Apply for PAR 09 220 Funding Number: PAR 09 220 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Innovations in Biomedical Computational Science and Technology Initiative (STTR R41/R42) Apply for PAR 09 221 Funding Number: PAR 09 221 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Optimization of Small Molecule Probes for the Nervous System (R21) Apply for PAR 09 251 Funding Number: PAR 09 251 Agency: National Institutes of Health Category: Education Health Funding Amount: $150,000 |
| Image guided Drug Delivery in Cancer (R01) Apply for PA 09 253 Funding Number: PA 09 253 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| The Biology of Estrogen Receptor Negative Breast Cancer in Various Racial and Ethnic Groups (U01) Apply for RFA CA 09 026 Funding Number: RFA CA 09 026 Agency: National Institutes of Health Category: Education Health Funding Amount: $667,000 |
| Nutrition and Physical Activity Research to Promote Cardiovascular and Pulmonary Health (R01) Apply for PA 09 243 Funding Number: PA 09 243 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Nutrition and Physical Activity Research to Promote Cardiovascular and Pulmonary Health (R21) Apply for PA 09 244 Funding Number: PA 09 244 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Optimization of Small Molecule Probes for the Nervous System (STTR R41) Apply for PAR 09 259 Funding Number: PAR 09 259 Agency: National Institutes of Health Category: Education Health Funding Amount: $150,000 |
| Optimization of Small Molecule Probes for the Nervous System (SBIR R43) Apply for PAR 09 260 Funding Number: PAR 09 260 Agency: National Institutes of Health Category: Education Health Funding Amount: $150,000 |
| Institutional Clinical and Translational Science Award (U54) Apply for RFA RM 09 019 Funding Number: RFA RM 09 019 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Limited Competition for Research Centers in Minority Institutions Infrastructure for Clinical and Translational Research (RCTR) U54 Apply for PAR 09 261 Funding Number: PAR 09 261 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Exploring Epigenomic Processes and Non Coding RNAs in HIV/AIDS (R01) Apply for RFA DA 10 010 Funding Number: RFA DA 10 010 Agency: National Institutes of Health Category: Education Health Funding Amount: $750,000 |
| Exploring Epigenomic Processes and Non Coding RNAs in HIV/AIDS (R21) Apply for RFA DA 10 011 Funding Number: RFA DA 10 011 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Targeted Library Synthesis and Screening at Novel Targets for Potential Drug Addiction Treatments and Research Tools (R21/R33) Apply for RFA DA 10 005 Funding Number: RFA DA 10 005 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) (R01) Apply for RFA GM 10 009 Funding Number: RFA GM 10 009 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Developing Research Capacity in Africa for Studies on HIV Associated Malignancies (D43) Apply for RFA CA 09 016 Funding Number: RFA CA 09 016 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Medications Development for Cannabis Related Disorders (R01) Apply for RFA DA 10 016 Funding Number: RFA DA 10 016 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Specialized Programs of Research Excellence (SPOREs) in Human Cancer for Years 2010, 2011 and 2012 (P50) Apply for PAR 10 003 Funding Number: PAR 10 003 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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