Opportunity Information: Apply for RFA DA 10 002
Apply for RFA DA 10 002
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Substance Use and Abuse among U.S. Military Personnel, Veterans and their Families (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.399 Cancer Control.
- This funding opportunity was created on Jul 29, 2009 and posted on Jul 28, 2009.
- Applicants must submit their applications by Dec 22, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Private institutions of higher education Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) County governments Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Special district governments For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) State governments Independent school districts Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The grant opportunity titled "Substance Use and Abuse among U.S. Military Personnel, Veterans and their Families (R21)" (Funding Opportunity Number RFA-DA-10-002) is a National Institutes of Health (NIH) discretionary research grant aimed at supporting early-stage, exploratory work on substance use issues affecting U.S. service members, recently separated veterans, and their families. It is jointly issued by the National Institute on Drug Abuse (NIDA), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), and the National Cancer Institute (NCI). The central idea is to speed up progress by funding pilot and feasibility studies that can generate preliminary data, test new approaches, or refine methods that may later grow into larger, full-scale projects.
From a scientific and public health standpoint, the FOA focuses on alcohol, tobacco, and other drug use and misuse, including both illicit substances and prescription medications. It also explicitly includes the link between substance use and associated mental health problems, reflecting the reality that substance use disorders often co-occur with conditions such as depression, anxiety, PTSD, and other behavioral health challenges that can arise during or after military service. The populations of interest include active duty personnel and those who have recently separated from service, with specific mention of troops connected to Iraq and Afghanistan deployments, as well as the family members who may be directly affected by these issues and related stressors.
This announcement uses the NIH R21 mechanism, which is designed for exploratory and developmental research rather than large, definitive trials. R21 awards typically support innovative concepts and early testing where investigators may not yet have extensive preliminary data, making this mechanism a good fit for rapid-start projects, new collaborations, or emerging questions in military and veteran health. The R21 is also presented as running in parallel with an R01 opportunity (DA-10-001) that has identical scientific scope but is intended for more mature, extensive projects. In practical terms, the R21 track is meant to seed ideas and generate evidence that can later justify bigger, longer-term R01-level research.
In terms of funding expectations, NIH and its partners planned a combined investment of about $7.0 million in total costs in Fiscal Year 2010 across both the R21 and the parallel R01 FOA, with an estimated 11 to 21 new awards total across the two announcements. For FY2010, the planned institute-level commitments were approximately $2.0 million from NIDA, $2.0 million from NIAAA, and $1.0 million from NCI. The Department of Veterans Affairs (VA) Clinical Science Research and Development Service (CSRD) anticipated committing up to an additional $2.0 million, but only to support the R01 FOA; the VA encouraged R21 applications but stated it would not fund R21 proposals. The listed award ceiling for this R21 opportunity is $200,000.
Eligibility is broad and includes many common research-performing and community-serving organizations. Eligible applicants include public and private institutions of higher education, nonprofits (including both 501(c)(3) and non-501(c)(3) entities), small businesses, for-profit organizations other than small businesses, and multiple levels of government such as state, county, city or township, special district governments, and certain public housing authorities. The eligibility list also explicitly extends to groups such as federally recognized tribal governments and other tribal organizations, Alaska Native and Native Hawaiian Serving Institutions, Hispanic Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based and community-based organizations, regional organizations, U.S. territories or possessions, and even non-U.S. entities (foreign organizations). There is no cost sharing or matching requirement, which lowers the barrier to entry for organizations that might not have significant non-federal funds to contribute.
Administratively, the opportunity was posted in late July 2009, with an original and current closing date of December 22, 2009, and an archive date of January 22, 2010. The activity category is listed under education and health, and the CFDA numbers connected to the opportunity reflect the participating NIH institutes program areas: 93.273 (Alcohol Research Programs), 93.279 (Drug Abuse and Addiction Research Programs), and 93.399 (Cancer Control). The NCI involvement aligns particularly well with the tobacco component and broader cancer control implications tied to nicotine dependence and tobacco use patterns in military and veteran populations.
Overall, this R21 FOA is best understood as a targeted pilot-research initiative meant to build momentum in understanding and addressing substance use and misuse within military-connected communities. It encourages studies that can clarify causes and risk factors (epidemiology and etiology), improve identification and screening, and develop or test prevention and treatment strategies, while also recognizing the frequent overlap with mental health concerns. The structure of a parallel R01 announcement reinforces that NIH was seeking both short, agile early studies (R21) and larger, confirmatory projects (R01) to advance this research area quickly and in a coordinated way.
FAQs: Substance Use and Abuse among U.S. Military Personnel, Veterans and their Families (R21) - RFA-DA-10-002
What is the title of this grant opportunity?
The opportunity is titled "Substance Use and Abuse among U.S. Military Personnel, Veterans and their Families (R21)."
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is RFA-DA-10-002.
Which agency is offering this grant?
This is a National Institutes of Health (NIH) discretionary research grant opportunity.
Which NIH institutes are jointly issuing the announcement?
The announcement is jointly issued by the National Institute on Drug Abuse (NIDA), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), and the National Cancer Institute (NCI).
What is the main purpose of this R21 opportunity?
The FOA is designed to speed progress by supporting early-stage, exploratory research (pilot and feasibility studies). The goal is to generate preliminary data, test new approaches, or refine methods that can later support larger, full-scale projects.
What research topics does the FOA focus on?
The FOA focuses on alcohol, tobacco, and other drug use and misuse. It includes illicit substances as well as prescription medications.
Does the FOA include the relationship between substance use and mental health?
Yes. The FOA explicitly includes links between substance use and associated mental health problems, recognizing that substance use disorders often co-occur with conditions such as depression, anxiety, PTSD, and other behavioral health challenges.
Who are the populations of interest?
The FOA targets U.S. military-connected populations, including active duty personnel, recently separated veterans, and their family members.
Are Iraq and Afghanistan deployments specifically mentioned?
Yes. The FOA specifically mentions troops connected to Iraq and Afghanistan deployments.
What grant mechanism is being used?
This announcement uses the NIH R21 mechanism, which is intended for exploratory and developmental research rather than large, definitive trials.
Why is an R21 a good fit for this topic area?
The R21 mechanism supports innovative concepts and early testing, including projects that may not yet have extensive preliminary data. This makes it suitable for rapid-start studies, new collaborations, and emerging questions in military and veteran health related to substance use.
Is there a related R01 opportunity with the same scope?
Yes. The R21 FOA runs in parallel with an R01 opportunity (DA-10-001) that has identical scientific scope but is intended for more mature and extensive projects.
How do the R21 and the parallel R01 relate in practical terms?
The R21 track is meant to seed ideas and generate evidence that can justify a bigger, longer-term R01-level research effort, while the R01 track supports larger, more developed projects within the same scientific area.
What is the award ceiling for this R21 opportunity?
The listed award ceiling for this R21 opportunity is $200,000.
How much total funding was planned across the R21 and R01 announcements?
NIH and its partners planned a combined investment of about $7.0 million in total costs in Fiscal Year 2010 across both the R21 and the parallel R01 FOA.
How many total awards were estimated across both announcements?
The estimate was approximately 11 to 21 new awards total across the two announcements (R21 and R01 combined).
What were the planned institute-level commitments for FY2010?
For FY2010, the planned commitments were approximately $2.0 million from NIDA, $2.0 million from NIAAA, and $1.0 million from NCI (across the combined effort described).
Was the Department of Veterans Affairs (VA) involved in funding?
The VA Clinical Science Research and Development Service (CSRD) anticipated committing up to an additional $2.0 million, but only to support the parallel R01 FOA. The VA encouraged R21 applications but stated it would not fund R21 proposals.
What types of organizations are eligible to apply?
Eligibility is broad and includes public and private institutions of higher education, nonprofits (501(c)(3) and non-501(c)(3)), small businesses, for-profit organizations other than small businesses, and multiple levels of government (state, county, city or township, special district governments, and certain public housing authorities).
Are tribal and minority-serving organizations included in eligibility?
Yes. The eligibility list explicitly includes federally recognized tribal governments and other tribal organizations, Alaska Native and Native Hawaiian Serving Institutions, Hispanic Serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Can faith-based or community-based organizations apply?
Yes. Faith-based and community-based organizations are explicitly listed as eligible applicants.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are included in the eligibility list.
Are foreign (non-U.S.) organizations eligible to apply?
Yes. The eligibility list explicitly includes non-U.S. entities (foreign organizations).
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
When was the opportunity posted?
The opportunity was posted in late July 2009.
What was the application closing date?
The original and current closing date listed is December 22, 2009.
When was the opportunity archived?
The archive date listed is January 22, 2010.
What activity categories are associated with this opportunity?
The activity category is listed under education and health.
Which CFDA numbers are connected to this opportunity?
The CFDA numbers associated with the participating NIH institute program areas are 93.273 (Alcohol Research Programs), 93.279 (Drug Abuse and Addiction Research Programs), and 93.399 (Cancer Control).
Why is the National Cancer Institute (NCI) involved?
NCI involvement aligns particularly with the tobacco component and broader cancer control implications tied to nicotine dependence and tobacco use patterns in military and veteran populations.
What kinds of studies does the FOA encourage?
The FOA encourages pilot-oriented studies that can clarify causes and risk factors (epidemiology and etiology), improve identification and screening, and develop or test prevention and treatment strategies, including work that accounts for co-occurring mental health concerns.
What is the overall takeaway for applicants deciding between R21 and R01?
This R21 FOA is best understood as a targeted pilot-research initiative for early, exploratory work. The parallel R01 announcement exists for larger, more confirmatory projects with the same scientific scope.
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