Opportunity Information: Apply for PA 14 128
Apply for PA 14 128
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Targeted Basic Behavioral and Social Science and Intervention Development for HIV Prevention and Care (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research.
- This funding opportunity was created on Feb 28, 2014 and posted on Feb 28, 2014.
- Applicants must submit their applications by Jan 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) County governments Public housing authorities/Indian housing authorities Small businesses Special district governments For profit organizations other than small businesses Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts State governments Private institutions of higher education Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIH grant opportunity "Targeted Basic Behavioral and Social Science and Intervention Development for HIV Prevention and Care (R21)" (Funding Opportunity Number PA-14-128) is designed to support innovative, targeted research that can reduce new HIV infections and improve health outcomes for people living with HIV. The announcement lays out priority areas for work at the intersection of behavioral and social science and practical intervention development, with a clear emphasis on moving from foundational understanding of behavior and social context into real-world prevention and care strategies. In practical terms, the FOA is looking for projects that explain why people do what they do in contexts relevant to HIV risk, testing, treatment uptake, and long-term care engagement, and then use those insights to build and refine interventions that can be tested.
The FOA encourages three broad types of research aims. First, it supports basic behavioral and social science research that fills key knowledge gaps needed to design stronger HIV prevention and care interventions. This includes studies that clarify behavioral drivers, decision-making processes, social and structural influences, stigma-related dynamics, relationship and network factors, and other psychosocial or contextual mechanisms that shape prevention and care behaviors. Second, it encourages applicants to translate and operationalize findings from basic studies into intervention concepts, prototypes, or strategies, including early-stage development work and feasibility assessments. That development phase can include refining intervention components, determining whether the approach is acceptable to the intended population, and testing whether delivery is practical in the settings where it would be used. Third, the FOA allows for tests of intervention efficacy, meaning projects can go beyond feasibility and examine whether a prevention or care intervention produces meaningful improvements in targeted outcomes, such as risk reduction behaviors, linkage to care, retention, medication adherence, or related health measures.
Because this is an R21 mechanism, the opportunity is oriented toward early, exploratory, or high-impact pilot work rather than large, long-term definitive trials. The goal is to generate actionable evidence and intervention approaches that are novel and targeted, and that can later be scaled up or positioned for larger studies if the early data are promising. The award ceiling is listed as $200,000, and the FOA explicitly states there is no cost sharing or matching requirement, which lowers the barrier for organizations that may not have flexible funding to contribute.
This funding opportunity is categorized as discretionary and uses a grant funding instrument. It sits within NIH health research activity areas and is associated with CFDA numbers 93.242 (Mental Health Research Grants), 93.855 (Allergy and Infectious Diseases Research), and 93.856 (Microbiology and Infectious Diseases Research), signaling that the scientific scope can cut across mental health, infectious disease, and broader HIV-related biomedical contexts as long as the work is grounded in behavioral and social science and intervention development relevant to HIV prevention and care.
Eligibility is broad and includes many types of applicants across public, private, nonprofit, and academic sectors. Eligible applicants include state, county, city or township governments; public and state-controlled institutions of higher education; private institutions of higher education; independent school districts; special district governments; tribal governments (federally recognized) and other tribal organizations; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status (including those outside higher education); small businesses; and other for-profit organizations. The FOA also identifies additional eligible entities such as faith-based and community-based organizations, historically Black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American, Native American, and Pacific Islander-serving institutions (AANAPISIs). Importantly, the announcement allows non-U.S. applicants as well: foreign organizations and foreign institutions may apply, non-U.S. components of U.S. organizations are eligible, and foreign components as defined by the NIH Grants Policy Statement are permitted. This reflects the global nature of the HIV epidemic and the value NIH places on research that can address diverse settings and populations.
In terms of timing, the FOA was posted and created on February 28, 2014, with an original and current closing date of January 7, 2017, and an archive date of February 7, 2017. That means the specific posting is no longer active for submission, but it remains useful as a reference point for NIH priorities and for locating successor funding opportunities with similar goals and mechanisms. The sponsoring agency is the National Institutes of Health, and the primary access point for the full announcement is provided via the NIH grants guide link (http://grants.nih.gov/grants/guide/pa-files/PA-14-128.html). For technical issues accessing the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Overall, PA-14-128 is centered on strengthening the pipeline from behavioral and social science discovery to tangible HIV prevention and care interventions, with support for both early development work and more advanced efficacy testing. The underlying expectation is that understanding behavior and social context is not an academic endpoint, but a practical foundation for building interventions that measurably reduce transmission risk, improve care engagement, and enhance the health and well-being of people living with HIV.
FAQs: NIH Targeted Basic Behavioral and Social Science and Intervention Development for HIV Prevention and Care (R21) (PA-14-128)
What is PA-14-128?
PA-14-128 is an NIH funding opportunity titled "Targeted Basic Behavioral and Social Science and Intervention Development for HIV Prevention and Care (R21)." It was designed to support innovative, targeted research that helps reduce new HIV infections and improves health outcomes for people living with HIV by linking behavioral and social science insights to practical intervention development.
What is the main purpose of this funding opportunity?
The purpose is to strengthen the pipeline from behavioral and social science discovery to real-world HIV prevention and care interventions. Projects are expected to explain behavior and social context in HIV-relevant settings and use that understanding to build, refine, and (in some cases) test interventions aimed at measurable improvements in prevention and care outcomes.
What kind of research does the FOA emphasize?
The FOA emphasizes research at the intersection of behavioral and social science and intervention development. It prioritizes work that moves from foundational understanding (why people behave as they do in HIV-related contexts) into practical strategies that can be used in prevention and care.
What are the three broad types of research aims encouraged by this FOA?
The FOA encourages: (1) basic behavioral and social science research that fills key knowledge gaps needed to design stronger HIV prevention and care interventions; (2) translating findings into intervention concepts, prototypes, or strategies, including early-stage development and feasibility work; and (3) tests of intervention efficacy to evaluate whether an intervention meaningfully improves targeted outcomes.
What does "basic behavioral and social science" mean in the context of this FOA?
In this FOA, basic behavioral and social science refers to studies that clarify behavioral drivers and decision-making processes, social and structural influences, stigma-related dynamics, relationship and network factors, and other psychosocial or contextual mechanisms that shape HIV prevention and care behaviors.
What does the FOA mean by translating basic findings into interventions?
Translation here means turning behavioral and social science findings into usable intervention concepts and delivery strategies. This can include developing and refining intervention components, assessing acceptability with the intended population, and determining whether delivery is practical in the settings where the intervention would be used.
Does this FOA allow efficacy testing of interventions?
Yes. Beyond feasibility and early-stage development, the FOA allows tests of intervention efficacy to examine whether an HIV prevention or care intervention produces meaningful improvements in outcomes such as risk reduction behaviors, linkage to care, retention in care, medication adherence, or related health measures.
What does the R21 mechanism imply for project scope?
Because this is an R21, the FOA is oriented toward early, exploratory, or high-impact pilot work rather than large, long-term definitive trials. The goal is to generate actionable evidence and novel, targeted intervention approaches that could later be scaled up or positioned for larger studies if early data are promising.
What is the award ceiling for this opportunity?
The FOA lists an award ceiling of $200,000.
Is cost sharing or matching required?
No. The FOA explicitly states there is no cost sharing or matching requirement.
What type of funding is this categorized as?
This opportunity is categorized as discretionary and uses a grant funding instrument.
Which agency sponsors this opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
Which CFDA numbers are associated with PA-14-128?
The FOA is associated with CFDA numbers 93.242 (Mental Health Research Grants), 93.855 (Allergy and Infectious Diseases Research), and 93.856 (Microbiology and Infectious Diseases Research).
Does the scientific scope have to be strictly within one CFDA area?
The associated CFDA numbers signal that the scientific scope may cut across mental health, infectious disease, and broader HIV-related biomedical contexts, as long as the proposed work is grounded in behavioral and social science and intervention development relevant to HIV prevention and care.
Who is eligible to apply?
Eligibility is broad and includes many public, private, nonprofit, and academic entities. Eligible applicants include state, county, city or township governments; public and state-controlled institutions of higher education; private institutions of higher education; independent school districts; special district governments; tribal governments (federally recognized) and other tribal organizations; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status; small businesses; and other for-profit organizations.
Are community-based and faith-based organizations eligible?
Yes. The FOA identifies faith-based and community-based organizations as eligible entities.
Are minority-serving institutions specifically mentioned as eligible?
Yes. The FOA specifically mentions eligible entities such as historically Black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American, Native American, and Pacific Islander-serving institutions (AANAPISIs).
Can foreign (non-U.S.) organizations apply?
Yes. The FOA allows non-U.S. applicants, including foreign organizations and foreign institutions. It also states that non-U.S. components of U.S. organizations are eligible and that foreign components (as defined by the NIH Grants Policy Statement) are permitted.
Why does the FOA allow foreign applicants and components?
The FOA frames this flexibility as consistent with the global nature of the HIV epidemic and NIH interest in research that can address diverse settings and populations.
When was PA-14-128 posted, and is it still open?
The FOA was posted and created on February 28, 2014. The original and current closing date listed is January 7, 2017, and the archive date is February 7, 2017. Based on these dates, the specific posting is no longer active for submission.
If it is archived, why is PA-14-128 still useful?
Even though it is no longer active, it remains useful as a reference point for NIH priorities in behavioral and social science and intervention development for HIV prevention and care, and for identifying successor funding opportunities with similar goals and mechanisms.
Where can I find the full announcement text?
The FOA can be accessed through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PA-14-128.html
Who should be contacted for technical issues accessing the announcement?
For technical issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What outcomes does the FOA highlight for prevention and care?
The FOA highlights outcomes including risk reduction behaviors, HIV testing and related decision-making, treatment uptake, linkage to care, retention in long-term care engagement, medication adherence, and related health measures for people living with HIV.
What is the underlying expectation for funded projects?
The FOA emphasizes that understanding behavior and social context is not an academic endpoint. The expectation is that these insights serve as a practical foundation for building interventions that measurably reduce transmission risk, improve care engagement, and enhance health and well-being for people living with HIV.
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