Opportunity Information: Apply for RFA HG 11 013
Apply for RFA HG 11 013
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Technology Development for High Throughput Functional Genomics (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research.
- This funding opportunity was created on May 23, 2011 and posted on May 23, 2011.
- Applicants must submit their applications by Aug 2, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $5,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Independent school districts For profit organizations other than small businesses Public and State controlled institutions of higher education State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments City or township governments Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Public housing authorities/Indian housing authorities Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Foreign (non U.S.) components of U.S. Organizations are allowed.
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Opportunity Summary:
The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), offered this discretionary grant opportunity to push forward technology development for high throughput functional genomics in eukaryotic genomes. The core aim is to support projects that create new or substantially improved methods to efficiently identify, validate, and characterize sequence-based functional elements across genomes at scale. In practical terms, the funding is meant to help researchers move beyond slow, piecemeal approaches and instead build tools and platforms that can comprehensively map and test functional DNA elements (for example, regulatory regions and other functional sequences) in a way that is both high throughput and broadly applicable. The announcement is explicitly positioned as part of a longer-running technology development track that began in 2003 under the ENCODE project, signaling that the emphasis is on enabling next-generation, genome-wide functional analysis rather than incremental biology-only studies.
This specific opportunity uses the R01 Research Project Grant mechanism, which generally supports more mature, hypothesis-driven or well-developed technology programs that require a sustained, multi-year research plan. NHGRI paired it with two companion announcements that share the same scientific scope but target different applicant needs and stages of development: an R21 Exploratory/Developmental mechanism (RFA-HG-11-014) for earlier-stage, higher-risk or proof-of-concept ideas, and an R43/R44 Small Business Innovation Research (SBIR) mechanism (RFA-HG-11-015) aimed at small businesses developing commercializable innovations. Together, the three tracks were designed to cover a pipeline from early exploration through robust research projects and into small-business translation, all focused on technology that makes functional genomics faster, more comprehensive, and more scalable.
Administratively, the funding opportunity number is RFA-HG-11-013 and the Catalog of Federal Domestic Assistance (CFDA) number is 93.172 (Human Genome Research). The program did not require cost sharing or matching funds. It was posted and created on May 23, 2011, with an original and current closing date of August 2, 2011, and an archive date of September 2, 2011. The estimated total funding associated with the announcement was $5,000,000, which indicates a competitive pool intended to support a limited number of technology-focused awards rather than a large volume of smaller projects.
Eligibility was broad and included many common research and public-sector applicants. Eligible organizations included public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including 501(c)(3) nonprofits and certain non-501(c)(3) nonprofits), for-profit organizations other than small businesses, and small businesses. Government entities at multiple levels were also eligible, including state governments, county governments, city or township governments, special district governments, public housing authorities/Indian housing authorities, and federally recognized Native American tribal governments as well as other tribal organizations. The announcement also explicitly broadened eligibility to include groups such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, U.S. territories or possessions, and regional organizations. Importantly, it allowed non-U.S. entities (foreign organizations) and foreign components of U.S. organizations, which can be relevant for international collaborations or specialized technology development conducted abroad.
For reference and full details, NHGRI provided an official announcement link through the NIH Grants Guide (http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-11-013.html). For access or technical issues related to the electronic announcement, the contact listed was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
What is the main purpose of this grant opportunity?
This funding opportunity from the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), is intended to advance technology development for high throughput functional genomics in eukaryotic genomes. The focus is on creating new or substantially improved methods that can efficiently identify, validate, and characterize sequence-based functional elements across genomes at scale.
What kinds of projects are this RFA trying to support?
The emphasis is on technology and method development that enables comprehensive, scalable mapping and testing of functional DNA elements across genomes. The announcement highlights moving beyond slow, piecemeal approaches and instead building tools and platforms that support genome-wide functional analysis in a high throughput way.
Does this opportunity focus on biology studies or technology development?
Based on the description provided, the opportunity is positioned as technology development oriented, aimed at enabling next-generation, genome-wide functional analysis rather than incremental biology-only studies.
What types of functional elements are included in scope?
The opportunity targets sequence-based functional elements across genomes. Examples mentioned include regulatory regions and other functional sequences.
What is the funding mechanism for this specific announcement?
This opportunity uses the NIH R01 Research Project Grant mechanism.
Why is an R01 being used for this program?
The R01 mechanism is described as generally supporting more mature, hypothesis-driven or well-developed technology programs that require a sustained, multi-year research plan.
Are there companion funding opportunities related to this one?
Yes. NHGRI paired this R01 opportunity with two companion announcements that share the same scientific scope but target different stages and applicant needs: an R21 Exploratory/Developmental mechanism (RFA-HG-11-014) and an R43/R44 Small Business Innovation Research (SBIR) mechanism (RFA-HG-11-015).
How do the R01, R21, and SBIR tracks fit together?
The three tracks were designed as a pipeline: the R21 supports earlier-stage, higher-risk or proof-of-concept ideas; the R01 supports more robust, sustained research projects; and the R43/R44 SBIR track supports small businesses developing commercializable innovations. All three focus on technologies that make functional genomics faster, more comprehensive, and more scalable.
What is the funding opportunity number (FOA/RFA number)?
The funding opportunity number is RFA-HG-11-013.
What is the CFDA number for this program?
The Catalog of Federal Domestic Assistance (CFDA) number is 93.172 (Human Genome Research).
How much total funding was estimated for this announcement?
The estimated total funding associated with the announcement was $5,000,000.
Does the total funding level suggest anything about the number or size of awards?
The provided description indicates the $5,000,000 total suggests a competitive pool intended to support a limited number of technology-focused awards rather than a large volume of smaller projects.
Is cost sharing or matching required?
No. The announcement did not require cost sharing or matching funds.
When was this funding opportunity posted and created?
It was posted and created on May 23, 2011.
What were the closing dates for this opportunity?
The original and current closing date was August 2, 2011.
When was the archive date?
The archive date was September 2, 2011.
Which NIH Institute offered this opportunity?
The opportunity was offered by the National Human Genome Research Institute (NHGRI), part of NIH.
How is this opportunity connected to ENCODE?
The announcement is described as part of a longer-running technology development track that began in 2003 under the ENCODE project, emphasizing next-generation, genome-wide functional analysis technology development.
Who is eligible to apply?
Eligibility was broad. Eligible organizations included public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits); for-profit organizations other than small businesses; and small businesses.
Are government entities eligible to apply?
Yes. Eligible government entities included state governments, county governments, city or township governments, special district governments, public housing authorities/Indian housing authorities, federally recognized Native American tribal governments, and other tribal organizations.
Are specific institution types like HBCUs and Hispanic-serving institutions eligible?
Yes. The announcement explicitly included groups such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and also faith-based or community-based organizations.
Are U.S. territories or regional organizations eligible?
Yes. The announcement explicitly broadened eligibility to include U.S. territories or possessions and regional organizations.
Are foreign organizations allowed to apply?
Yes. The opportunity allowed non-U.S. entities (foreign organizations) and also allowed foreign components of U.S. organizations.
Where can applicants find the official announcement?
The official announcement was provided through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-11-013.html
Who should be contacted for access or technical issues with the electronic announcement?
For access or technical issues related to the electronic announcement, the listed contact was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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