Opportunity Information: Apply for PA 15 050
Apply for PA 15 050
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Underactive Bladder in Aging (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Nov 24, 2014 and posted on Nov 24, 2014.
- Applicants must submit their applications by Jan 7, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $50,000.00 in funding.
- Eligible applicants include: State governments Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Small businesses For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Independent school districts Public housing authorities/Indian housing authorities County governments Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Underactive Bladder in Aging (R03) opportunity (Funding Opportunity Number: PA-15-050) is a National Institutes of Health (NIH) pilot/feasibility grant designed to jump-start early, smaller-scale research projects focused on underactive bladder (UAB) in the context of aging. The intent is to support studies that can quickly generate preliminary data, test methods, and demonstrate feasibility for diagnosing, evaluating, and potentially treating UAB in older adults, while also strengthening the scientific foundation needed for larger future projects. The FOA is open to basic, clinical, and translational approaches, with an emphasis on how UAB develops with advancing age and how it affects health and functioning in older people.
The FOA highlights four main scientific directions that applicants are expected to align with. First, it encourages work on the biology, etiology, and pathophysiology of UAB, including mechanistic studies in animal models and/or research directly involving older adults. This can include examining how aging affects bladder muscle contractility, nerve signaling, bladder outlet function, and the broader changes in tissues and systems that might contribute to underactivity. Second, it supports translation of basic and clinical findings into clinical practice and health decision making, meaning projects that help bridge the gap between discoveries and real-world care, such as developing clinically meaningful assessment strategies or decision tools. Third, it emphasizes diagnosis, prevention, management, and clinical outcomes of UAB in older adults, including practical studies that explore how to identify UAB earlier, reduce complications, or improve management approaches while measuring patient-centered outcomes. Fourth, it encourages epidemiology and risk-factor research to clarify how common UAB is with aging, what factors predict its onset or progression, and which groups are most at risk as they get older.
Because this is an R03 mechanism, the projects are intended to be modest in scope and specifically framed as pilot or feasibility work rather than large definitive trials. The FOA frames success in terms of improving knowledge about UAB in older adults and producing credible evidence that a proposed diagnostic approach, evaluation strategy, or intervention concept can be implemented and studied. In practice, that means applications should be built around focused aims, clear feasibility milestones, and outcomes that demonstrate whether a method, measure, recruitment strategy, or preliminary intervention is workable and informative in an aging population.
From an administrative standpoint, the announcement is categorized as a discretionary grant in the health area (CFDA 93.866, Aging Research). It does not require cost sharing or matching. The award ceiling listed is $50,000, reflecting the small, pilot nature of the R03. The opportunity was posted and created on November 24, 2014, with the original and current closing date listed as January 7, 2018, and an archive date of February 7, 2018, indicating it is no longer active but remains relevant as a reference point for NIH priorities and for understanding how similar future opportunities may be structured.
Eligibility is broad and includes many types of organizations that commonly apply to NIH grants. Eligible applicants include public and private institutions of higher education, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), state and local governments (including counties, cities/townships, special districts, and independent school districts), tribal governments and tribal organizations, public housing authorities/Indian housing authorities, small businesses, and other for-profit organizations. The eligibility language also explicitly includes a wide range of mission-focused institutions and organizations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, U.S. territories or possessions, and even non-U.S. entities (foreign organizations) and regional organizations, reflecting NIH interest in encouraging diverse research settings and perspectives where appropriate.
The sponsoring agency is NIH, and the full announcement was made available through the NIH grants guide (link provided in the source: http://grants.nih.gov/grants/guide/pa-files/PA-15-050.html). For technical issues accessing the announcement, NIH directed applicants to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.
Frequently Asked Questions (FAQs)
What is the "Underactive Bladder in Aging (R03)" funding opportunity?
It is an NIH pilot/feasibility grant opportunity focused on underactive bladder (UAB) in the context of aging. It is intended to jump-start early, smaller-scale research projects that can quickly generate preliminary data, test methods, and demonstrate feasibility for diagnosing, evaluating, and potentially treating UAB in older adults.
What is the Funding Opportunity Number (FON) for this announcement?
The Funding Opportunity Number is PA-15-050.
What NIH grant mechanism does this opportunity use?
This opportunity uses the NIH R03 mechanism, which is typically used for small, focused projects framed as pilot or feasibility studies rather than large, definitive trials.
What is the overall purpose of an R03 in this context?
The R03 is meant to support modest-scope projects that can strengthen the scientific foundation for larger future projects. For this specific FOA, success is framed around improving knowledge about UAB in older adults and producing credible evidence that a diagnostic approach, evaluation strategy, or intervention concept can be implemented and studied.
What types of research approaches are encouraged?
The FOA is open to basic, clinical, and translational approaches, with an emphasis on understanding how UAB develops with advancing age and how it affects health and functioning in older people.
What are the main scientific directions applicants are expected to align with?
The FOA highlights four main directions: (1) biology, etiology, and pathophysiology of UAB; (2) translation of basic and clinical findings into clinical practice and health decision making; (3) diagnosis, prevention, management, and clinical outcomes of UAB in older adults; and (4) epidemiology and risk-factor research related to UAB and aging.
What does the FOA mean by studying the biology, etiology, and pathophysiology of UAB?
This includes mechanistic studies in animal models and/or research directly involving older adults. Examples mentioned include examining how aging affects bladder muscle contractility, nerve signaling, bladder outlet function, and broader tissue or system changes that may contribute to bladder underactivity.
What kinds of projects fit under "translation into clinical practice and health decision making"?
Projects that bridge discoveries and real-world care, such as developing clinically meaningful assessment strategies or decision tools that could help inform evaluation and management of UAB in clinical settings.
What does the FOA emphasize related to diagnosis, prevention, management, and outcomes?
It emphasizes practical studies in older adults that explore how to identify UAB earlier, reduce complications, or improve management approaches, while measuring patient-centered outcomes.
What is meant by epidemiology and risk-factor research in this FOA?
This direction focuses on clarifying how common UAB is with aging, identifying factors that predict onset or progression, and determining which groups are most at risk as they get older.
How big should an R03 project be under this FOA?
Projects are expected to be modest in scope and specifically framed as pilot or feasibility work. The FOA suggests focused aims, clear feasibility milestones, and outcomes that show whether a method, measure, recruitment strategy, or preliminary intervention is workable in an aging population.
What kinds of deliverables or outcomes does the FOA appear to value?
Based on the description, the FOA values outcomes such as preliminary data, tested methods, demonstrated feasibility, and credible evidence that a proposed diagnostic approach, evaluation strategy, or intervention concept can be implemented and studied among older adults.
What is the award ceiling for this opportunity?
The award ceiling listed is $50,000, reflecting the small, pilot nature of the R03 mechanism described in the opportunity summary.
Is cost sharing or matching required?
No. The opportunity summary states that it does not require cost sharing or matching.
What is the CFDA number and program area listed for this opportunity?
It is listed under CFDA 93.866, Aging Research.
Which agency sponsors this funding opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
When was this opportunity posted and created?
It was posted and created on November 24, 2014.
What were the closing and archive dates shown for this opportunity?
The original and current closing date is listed as January 7, 2018, and the archive date is February 7, 2018.
Is this funding opportunity still active?
No. The archive date and the listed closing date indicate the opportunity is no longer active, though it can still be useful as a reference point for NIH priorities and how similar opportunities may be structured.
Who is eligible to apply?
Eligibility is broad and includes public and private institutions of higher education; nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status); state and local governments (including counties, cities/townships, special districts, and independent school districts); tribal governments and tribal organizations; public housing authorities/Indian housing authorities; small businesses; and other for-profit organizations.
Does the FOA explicitly encourage applications from mission-focused or underrepresented institution types?
Yes. The eligibility language explicitly includes many institution types such as HBCUs, Hispanic-serving institutions, TCCUs, Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, faith-based or community-based organizations, and U.S. territories or possessions.
Are foreign organizations eligible to apply?
Yes. The eligibility description explicitly includes non-U.S. entities (foreign organizations) and regional organizations.
Where can the full FOA text be found?
The full announcement is available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PA-15-050.html
Who should be contacted for technical issues accessing the announcement?
For technical issues accessing the announcement, NIH directed applicants to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.
What topic area does this opportunity focus on?
It focuses on underactive bladder (UAB) in aging, including how it develops with advancing age and how it affects health and functioning in older people.
Does the opportunity allow both animal model and human research?
Yes. The FOA explicitly mentions mechanistic studies in animal models and/or research directly involving older adults.
Does the FOA prioritize large clinical trials?
No. The description emphasizes that, as an R03 mechanism, projects should be modest in scope and framed as pilot or feasibility work rather than large definitive trials.
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