Opportunity Information: Apply for PA 08 254
Apply for PA 08 254
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Unique Interactions Between Tobacco Use and HIV/AIDS (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs 93.989 International Research and Research Training.
- This funding opportunity was created on Oct 3, 2008 and posted on Oct 3, 2008.
- Applicants must submit their applications by Sep 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Special district governments County governments For profit organizations other than small businesses State governments Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Private institutions of higher education Small businesses Public housing authorities/Indian housing authorities City or township governments Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
This funding opportunity, PA 08 254, titled "Unique Interactions Between Tobacco Use and HIV/AIDS (R03)," is a discretionary NIH grant program designed to spark focused, smaller-scale studies on how cigarette smoking and HIV/AIDS interact to affect health. It is sponsored by the National Institute on Drug Abuse (NIDA) together with the Fogarty International Center (FIC), reflecting both a substance use focus and an interest in research and capacity that may include international settings. The core aim is not simply to study tobacco use or HIV in isolation, but to encourage research that looks at the combined or synergistic effects of smoking in people living with HIV or at how HIV infection might change the health consequences of smoking. In practical terms, the program is looking for projects that can clarify unique risks, mechanisms, clinical outcomes, or public health implications that arise specifically from the overlap of tobacco exposure and HIV disease.
The award uses the NIH Small Research Grant (R03) mechanism, which generally supports short-term, limited-scope projects such as pilot studies, feasibility work, secondary analyses, early-stage hypothesis testing, or the development of preliminary data that could later support a larger application. This FOA runs in parallel with a companion announcement of the same scientific scope that uses the R01 mechanism (PA 08 253), meaning investigators with larger, more mature projects could pursue the full research project grant route, while this R03 track is meant to lower the barrier for exploratory ideas and targeted studies that can be done with a smaller budget and a shorter timeline.
Funding levels and the number of awards are not fixed in advance. The announcement makes clear that award size and project duration will vary depending on what is proposed, and that the total funding and total awards ultimately depend on the number of applications received, their scientific merit, the requested budgets, and project periods. There is no cost sharing or matching requirement, which is typical for NIH research grants and reduces financial barriers for applicants.
Eligibility is broad and includes many types of domestic U.S. organizations as well as non-U.S. entities. Eligible applicants explicitly include public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) organizations), for-profit organizations other than small businesses as well as small businesses, and a wide range of government entities such as state governments, county governments, city or township governments, special district governments, and public housing authorities or Indian housing authorities. The FOA also emphasizes inclusion of Tribal governments (both federally recognized and other than federally recognized) and tribally controlled colleges and universities. In addition, it identifies several categories often highlighted in NIH eligibility language, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations. It also allows regional organizations, U.S. territories or possessions, and foreign organizations (non-U.S. entities), which aligns well with Fogarty's international research and research training mission.
From an administrative standpoint, the opportunity was posted and created on October 3, 2008, with an original and final closing date of September 7, 2011, and it was archived on October 8, 2011. The relevant CFDA program areas listed are 93.279 (Drug Abuse and Addiction Research Programs) and 93.989 (International Research and Research Training), which helps signal the programmatic lanes NIH may use to track the portfolio and the kinds of institutes and centers most directly aligned with the topic. Applicants seeking the complete archived announcement were directed to the NIH Grants Guide link provided in the notice, and technical access issues were routed to the NIH Office of Extramural Research (OER) webmaster contact.
Overall, the opportunity is best understood as an NIH call for concise, well-defined research projects that can quickly generate evidence about how smoking and HIV/AIDS jointly influence disease progression, comorbidities, treatment outcomes, or other health endpoints, with a structure (R03) that favors efficient, hypothesis-driven work that can stand alone or serve as a springboard to an R01-scale study.
FAQs: PA-08-254 - Unique Interactions Between Tobacco Use and HIV/AIDS (R03)
What is PA-08-254?
PA-08-254 is an NIH discretionary funding opportunity titled "Unique Interactions Between Tobacco Use and HIV/AIDS (R03)." It supports smaller, focused research studies that examine how cigarette smoking and HIV/AIDS interact to affect health, especially effects that are unique to their overlap rather than either factor alone.
What is the main purpose of this funding opportunity?
The goal is to generate evidence about combined or synergistic effects of tobacco use and HIV/AIDS. Projects are expected to clarify unique risks, mechanisms, clinical outcomes, or public health implications that arise specifically when smoking and HIV disease intersect.
What kinds of research questions fit this program?
Based on the description, strong-fit questions are those that focus on the overlap of smoking and HIV, such as how smoking influences HIV-related disease progression, comorbidities, or treatment outcomes, or how HIV infection changes the health consequences of smoking. The emphasis is on interaction effects, not studying tobacco or HIV in isolation.
Which NIH grant mechanism is used?
This opportunity uses the NIH Small Research Grant (R03) mechanism, which is intended for short-term, limited-scope projects.
What types of projects are typically appropriate for an R03 under this announcement?
The R03 mechanism generally supports projects such as pilot studies, feasibility studies, secondary data analyses, early-stage hypothesis testing, or work designed to develop preliminary data that could support a future, larger application.
Is there a related funding opportunity for larger projects?
Yes. This R03 opportunity runs in parallel with a companion announcement with the same scientific scope using the R01 mechanism (PA-08-253). The R01 route is typically more appropriate for larger, more mature projects, while the R03 is positioned for exploratory or targeted studies with smaller budgets and shorter timelines.
Who sponsors this funding opportunity?
The opportunity is sponsored by the National Institute on Drug Abuse (NIDA) together with the Fogarty International Center (FIC). This pairing reflects an emphasis on substance use research and an interest that may include international research settings and capacity considerations.
Is the program limited to U.S.-based research settings?
No. Eligibility includes non-U.S. entities (foreign organizations), which aligns with Fogarty International Center interests and suggests the program can accommodate projects that may include international settings.
Are non-U.S. organizations eligible to apply?
Yes. The eligible applicant types explicitly include foreign organizations (non-U.S. entities).
What types of U.S. organizations are eligible to apply?
Eligibility is broad and includes public and private institutions of higher education; nonprofits (including 501(c)(3) and certain non-501(c)(3) organizations); for-profit organizations (including small businesses and for-profits other than small businesses); and many government entities such as state, county, and city or township governments, special district governments, and public housing authorities or Indian housing authorities.
Are Tribal governments and tribally controlled institutions included in eligibility?
Yes. The announcement emphasizes inclusion of Tribal governments (federally recognized and other than federally recognized) and tribally controlled colleges and universities.
Does the FOA mention any specific institution categories encouraged or highlighted?
Yes. It identifies categories commonly highlighted in NIH eligibility language, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations.
Are U.S. territories or regional organizations eligible?
Yes. The FOA allows regional organizations and U.S. territories or possessions.
How much funding is available per award?
The funding levels are not fixed in advance. Award size varies depending on what is proposed, and total funding depends on factors such as the number of applications received, their scientific merit, requested budgets, and proposed project periods.
How many awards will be made?
The number of awards is not specified. The total awards depend on application volume, scientific merit, budgets requested, and project durations.
Is there a required match or cost sharing?
No. The announcement states there is no cost sharing or matching requirement.
What is the timeframe for this opportunity (is it still open)?
This opportunity was posted and created on October 3, 2008. It had an original and final closing date of September 7, 2011, and it was archived on October 8, 2011. Based on those dates, it is not currently open.
Where can someone find the full archived announcement?
The notice indicates applicants were directed to the NIH Grants Guide link provided in the announcement to access the complete archived FOA.
What are the CFDA numbers associated with this funding opportunity?
The CFDA program areas listed are 93.279 (Drug Abuse and Addiction Research Programs) and 93.989 (International Research and Research Training).
What do the CFDA numbers suggest about the program focus?
They signal that the opportunity sits at the intersection of drug abuse/addiction research programming and international research and research training-related tracking lanes, consistent with NIDA and Fogarty International Center involvement.
What should an applicant emphasize to align with the core aim?
Applicants should emphasize the unique interaction between tobacco exposure and HIV/AIDS, such as combined effects on disease progression, comorbidities, treatment outcomes, or other health endpoints. The stated priority is research that addresses the overlap and interaction, not tobacco-only or HIV-only questions.
What is the administrative contact mentioned for technical access issues?
Technical access issues were routed to the NIH Office of Extramural Research (OER) webmaster contact, as referenced in the announcement.
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| Brain Imaging Studies of Negative Reinforcement in Humans (R01) Apply for RFA DA 09 008 Funding Number: RFA DA 09 008 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Brain Imaging Studies of Negative Reinforcement in Humans (R21) Apply for RFA DA 09 009 Funding Number: RFA DA 09 009 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Instrument Development for Biomedical Applications (R21) Apply for RFA RR 09 001 Funding Number: RFA RR 09 001 Agency: National Institutes of Health Category: Education Health Funding Amount: $125,000 |
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