Opportunity Information: Apply for PAR 10 190
Apply for PAR 10 190
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Vulvodynia Systematic Epidemiologic, Etiologic or Therapeutic Studies (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on May 7, 2010 and posted on May 7, 2010.
- Applicants must submit their applications by Sep 21, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Private institutions of higher education Independent school districts City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) County governments State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Small businesses Public and State controlled institutions of higher education For profit organizations other than small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The NIH funding opportunity PAR 10 190, titled "Vulvodynia - Systematic Epidemiologic, Etiologic or Therapeutic Studies (R01)," supports investigator-initiated research aimed at improving what is known about vulvodynia and closely related symptom-based conditions. Vulvodynia is described in the announcement as a chronic pelvic pain condition in women, and the central intent of the program is to stimulate new, rigorous research that can move the field forward on diagnosis, prevention, and treatment. Projects can be basic, clinical, translational, epidemiological, and/or behavioral in nature, reflecting a broad interest in studies that range from underlying mechanisms to real-world patient outcomes and interventions.
The FOA emphasizes building a stronger evidence base about several key areas: the pathophysiology of vulvodynia (how and why it develops and persists biologically), biologic and behavioral risk factors (including exposures, comorbidities, or psychosocial contributors that may increase risk or worsen symptoms), the natural history of the condition (how symptoms evolve over time and what predicts improvement versus persistence), and genetics. The expected outcome is not simply descriptive knowledge, but findings that can realistically inform future prevention strategies or therapeutic approaches. In other words, NIH is looking for studies that can clarify causes and contributors, improve identification and classification, and point toward practical ways to reduce incidence, severity, or long-term impact.
This particular announcement uses the NIH Research Project Grant (R01) mechanism, which is generally intended for mature, hypothesis-driven projects with a well-developed research plan and sufficient scope to produce definitive results. The FOA notes that it runs in parallel with two related opportunities that share the same scientific scope but use different mechanisms: PAR 10 191 (R03) for small, limited-scope studies and PAR 10 192 (R21) for exploratory or developmental work. That structure signals that NIH is trying to encourage a pipeline of work in vulvodynia research, from early-stage concept testing (R21), to smaller targeted studies (R03), to larger, more comprehensive projects (R01).
Funding levels and the number of awards are not specified as fixed amounts. Instead, NIH indicates that award size and duration will vary depending on the nature and scope of the proposed project, and that the total number of awards and total dollars awarded will ultimately depend on the quality of the applications received, their costs, and their proposed timelines. There is no cost sharing or matching requirement, which reduces barriers for applicants and aligns with typical NIH research grant practices.
Eligibility is broad and includes many types of domestic and non-domestic organizations. Eligible applicants include public and private institutions of higher education, nonprofits with or without 501(c)(3) status, for-profit organizations (including small businesses and other for-profits), and a wide range of government entities such as state, county, city or township governments, special districts, independent school districts, and public housing authorities (including Indian housing authorities). The announcement also explicitly includes tribal governments and tribal organizations, and it extends eligibility to foreign organizations and other non-U.S. entities, as well as U.S. territories or possessions and regional organizations. It also highlights inclusion of institutions serving historically underrepresented groups and community-based organizations, such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities, and faith-based or community-based organizations, among others.
Key administrative details listed in the source data include the posting and creation date of May 7, 2010, an original and current closing date of September 21, 2012, and an archive date of October 21, 2012, indicating this specific FOA is no longer active but remains relevant as a reference for the types of projects NIH sought under this initiative. The awarding agency is the National Institutes of Health, and the CFDA number given is 93.865, associated with Child Health and Human Development Extramural Research. The full announcement was made available via the NIH grants guide, and contact points were provided through NIH Grants Info and the NIH Office of Extramural Research webmaster for access or technical issues.
Frequently Asked Questions (FAQs)
What is the funding opportunity PAR 10-190?
PAR 10-190 is an NIH Funding Opportunity Announcement (FOA) titled "Vulvodynia - Systematic Epidemiologic, Etiologic or Therapeutic Studies (R01)." It supports investigator-initiated research designed to strengthen what is known about vulvodynia and closely related symptom-based conditions.
What condition is the FOA focused on?
The FOA focuses on vulvodynia, described in the announcement as a chronic pelvic pain condition in women, and also considers closely related symptom-based conditions.
What is NIH trying to accomplish through this program?
The central intent is to stimulate new, rigorous research that can move the field forward on diagnosis, prevention, and treatment. NIH is looking for studies that go beyond description and produce findings that can realistically inform future prevention strategies or therapeutic approaches.
What types of research projects are supported under this FOA?
The FOA supports a broad range of investigator-initiated projects, including basic, clinical, translational, epidemiological, and behavioral studies. This reflects interest in work spanning underlying mechanisms as well as real-world patient outcomes and interventions.
What scientific topics does the FOA emphasize?
The FOA emphasizes building a stronger evidence base in areas including:
- Pathophysiology of vulvodynia (how and why it develops and persists biologically)
- Biologic and behavioral risk factors (including exposures, comorbidities, and psychosocial contributors)
- Natural history (how symptoms change over time and what predicts improvement versus persistence)
- Genetics
What kinds of outcomes is NIH looking for from funded studies?
NIH is looking for results that can clarify causes and contributors, improve identification and classification, and point toward practical ways to reduce incidence, severity, or long-term impact. The expectation is that findings can help inform future prevention or treatment approaches.
What grant mechanism is used for PAR 10-190?
PAR 10-190 uses the NIH Research Project Grant (R01) mechanism, which is generally intended for mature, hypothesis-driven projects with well-developed research plans and enough scope to produce definitive results.
Are there related NIH opportunities with the same scientific scope?
Yes. The FOA runs in parallel with two related opportunities that share the same scientific scope but use different mechanisms:
- PAR 10-191 (R03) for small, limited-scope studies
- PAR 10-192 (R21) for exploratory or developmental work
Why does NIH offer R21, R03, and R01 options for the same topic area?
The structure suggests NIH wanted to encourage a pipeline of vulvodynia research, moving from early-stage concept testing (R21), to smaller targeted studies (R03), to larger, more comprehensive projects (R01).
How much funding is available under this FOA?
Funding levels are not specified as fixed amounts. NIH indicates award size and duration will vary depending on the nature and scope of the proposed project.
How many awards will NIH make under PAR 10-190?
The number of awards and total dollars awarded are not specified. NIH indicates this will depend on the quality of applications received, their costs, and their proposed timelines.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad and includes many types of domestic and non-domestic organizations. Eligible applicants include public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (including small businesses), and numerous government entities.
Are government entities eligible applicants?
Yes. The FOA includes eligibility for government entities such as state, county, city or township governments, special districts, independent school districts, and public housing authorities (including Indian housing authorities).
Are tribal governments and tribal organizations eligible?
Yes. The FOA explicitly includes tribal governments and tribal organizations among eligible applicants.
Are foreign (non-U.S.) organizations eligible to apply?
Yes. The FOA extends eligibility to foreign organizations and other non-U.S. entities.
Are U.S. territories or possessions included in eligibility?
Yes. The FOA includes U.S. territories or possessions and also references regional organizations as eligible.
Does the FOA encourage applications from institutions serving historically underrepresented groups?
Yes. The FOA highlights inclusion of institutions and organizations such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities, and faith-based or community-based organizations.
Is this funding opportunity still active?
No. The administrative details indicate this specific FOA is no longer active. It has an original and current closing date of September 21, 2012, and an archive date of October 21, 2012.
When was PAR 10-190 posted?
The posting and creation date listed is May 7, 2010.
What agency is offering this opportunity?
The awarding agency is the National Institutes of Health (NIH).
What CFDA number is associated with this opportunity?
The CFDA number provided is 93.865, associated with Child Health and Human Development Extramural Research.
Where was the full announcement made available?
The FOA was made available via the NIH grants guide.
Who are the listed contact points for access or technical issues?
The source information notes contact points via NIH Grants Info and the NIH Office of Extramural Research webmaster for access or technical issues.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 10 190) also looked into and applied for these:
| Funding Opportunity |
|---|
| Vulvodynia Systematic Epidemiologic, Etiologic or Therapeutic Studies (R21) Apply for PAR 10 192 Funding Number: PAR 10 192 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Vulvodynia Systematic Epidemiologic, Etiologic or Therapeutic Studies (R03) Apply for PAR 10 191 Funding Number: PAR 10 191 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Natural History of Disorders Identifiable by Newborn Screening (R01) Apply for RFA HD 10 019 Funding Number: RFA HD 10 019 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $1,000,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Predoctoral Training Program in Systems Biology of Developmental Biology and Birth Defects(T32) Apply for PAR 10 193 Funding Number: PAR 10 193 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Predoctoral and Postdoctoral Training Program in Reproductive, Obstetric, Perinatal and Pediatric Epidemiology and Pharmacoepidemiology (T32) Apply for PAR 10 194 Funding Number: PAR 10 194 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Postdoctoral Research Training for Obstetricians and Gynecologists (T32) Apply for PAR 10 203 Funding Number: PAR 10 203 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Biophysical and Biomechanical Aspects of Embryonic Development (R21) Apply for PAR 10 222 Funding Number: PAR 10 222 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $200,000 |
| Biophysical and Biomechanical Aspects of Embryonic Development (R01) Apply for PAR 10 221 Funding Number: PAR 10 221 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Safe and Effective Instruments and Devices for Use in the Neonatal Intensive Care Units (SBIR R43) Apply for RFA HD 10 012 Funding Number: RFA HD 10 012 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $225,000 |
| Safe and Effective Instruments and Devices for Use in the Neonatal Intensive Care Units (STTR R41) Apply for RFA HD 10 013 Funding Number: RFA HD 10 013 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $225,000 |
| Innovative Therapies and Tools for Screenable Disorders in Newborns (R03) Apply for PAR 10 231 Funding Number: PAR 10 231 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Developmental Mechanisms of Human Structural Birth Defects (P01) Apply for RFA HD 10 006 Funding Number: RFA HD 10 006 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $900,000 |
| NICHD Program Project Grant (P01) Apply for PAR 10 245 Funding Number: PAR 10 245 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Molecular Mechanisms of Adverse Metabolic Drug Effects in Children and Adolescents (R01) Apply for RFA HD 10 010 Funding Number: RFA HD 10 010 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $250,000 |
| Dual Purpose with Dual Benefit Research in Biomedicine and Agriculture Using Agriculturally Important Domestic Species (R01) Apply for PAR 10 276 Funding Number: PAR 10 276 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Identifying and Understanding Effective Interventions for Orphans and Vulnerable Children Affected by HIV/AIDS (R01) Apply for RFA HD 10 017 Funding Number: RFA HD 10 017 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Preclinical Research on Model Organisms to Predict Treatment Outcomes for Disorders Associated with Intellectual and Developmental Disabilities (R01) Apply for PAR 11 038 Funding Number: PAR 11 038 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Understanding and Treating Co Morbid Conditions in Adolescents with Intellectual and Developmental Disabilities (R01) Apply for PA 11 039 Funding Number: PA 11 039 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Understanding and Treating Co Morbid Conditions in Adolescents with Intellectual and Developmental Disabilities (R03) Apply for PA 11 040 Funding Number: PA 11 040 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Understanding and Treating Co Morbid Conditions in Adolescents with Intellectual and Developmental Disabilities (R21) Apply for PA 11 041 Funding Number: PA 11 041 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $200,000 |
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