Opportunity Information: Apply for CDC RFA PS14 1415

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Economic Modeling for HIV, Viral Hepatitis, Sexually Transmitted Diseases, Tuberculosis and School Health" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084 Prevention of Disease, Disability, and Death by Infectious Diseases.
  • This funding opportunity was created on Jul 8, 2014 and posted on May 21, 2014.
  • Applicants must submit their applications by Jul 17, 2014 1.Letter of Intent (LOI) Deadline June 16, 2014. 2.Application Deadline July 17, 2014, 1159 p.m. U.S. Eastern Daylight Time, on www.grants.gov. 3.Informational conference call for potential applicants June 3, 2014, 100 pm (EDT) to 200 pm (EDT), Conference call line 1 866 816 3094, participant passcode 3867397.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $15,000,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Private and public colleges and universities Government Organizations State or their bona fide agents (includes the District of Columbia) Local governments or their bona fide agents Territorial governments or their bona fide agents in the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau) State controlled institutions of higher education American Indian or Alaska Native tribal governments (federally recognized or state recognized) Public Housing Authorities/Indian Housing Authorities Non government Organizations American Indian or Alaska native tribally designated organizations Nonprofit with 501C3 IRS status (other than institution of higher education) Nonprofit without 501C3 IRS status (other than institution of higher education) Community based organizations Faith based organizations For profit organizations (other than small business) Small businesses.
Apply for CDC RFA PS14 1415

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Opportunity Summary:

The CDC funding opportunity titled "Economic Modeling for HIV, Viral Hepatitis, Sexually Transmitted Diseases, Tuberculosis and School Health" (Funding Opportunity Number: CDC-RFA-PS14-1415) is a discretionary cooperative agreement designed to strengthen how public health agencies and partners make prevention decisions. The central idea is that well-built models and timely economic analyses help CDC and its National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) compare policy options, decide how to allocate limited resources, estimate the likely impact of interventions, and understand whether interventions are cost-effective. In practice, this means supporting analytic work that can quickly answer high-priority questions that come up as prevention programs, clinical recommendations, and public behaviors change.

The work CDC expects to be supported is focused on producing models and economic results across five program areas: HIV, viral hepatitis, sexually transmitted diseases, tuberculosis, and school health. The analyses envisioned include estimating how disease incidence or prevalence might shift when key drivers change, such as sexual behaviors (for example, condom use, uptake of pre-exposure prophylaxis, or changes in antiretroviral therapy use), health-seeking behaviors (like increased HIV or hepatitis C testing), the rollout or discontinuation of specific interventions, or shifts in prevention funding and program intensity. Applicants are also expected to be capable of traditional economic assessments such as estimating the cost of illness (the economic burden associated with these conditions), calculating the costs of intervention strategies and health programs, and conducting cost-effectiveness analyses. Cost-effectiveness work may use quality-adjusted life years (QALYs) when comparing across different health problems, or it may use more natural units such as cases detected, infections averted, or patients treated when comparing alternative approaches within a specific disease area.

A major theme of the opportunity is decision support: building and using models to help determine optimal allocation of resources across diseases, interventions, and populations, and to estimate the overall population-level impact and value of prevention activities funded or supported by NCHHSTP. Another key deliverable area is return on investment and net benefit analyses, which are meant to translate public health strategies into economic terms that can inform program planning, policy decisions, and recommendations. Because CDC anticipates needing a range of analytic approaches depending on the question, the opportunity implies flexibility in methods, as long as applicants can produce rigorous, defensible results that are usable for real-world public health decision-making.

To be competitive, applicants are expected to show proven experience in economic modeling and analysis, with a demonstrated track record in at least two of the five areas (HIV, viral hepatitis, TB, STDs, and school health). This experience must be evidenced by prior peer-reviewed modeling or economic studies published in journals indexed in PubMed or EconLit. Beyond that minimum, applicants should have enough epidemiologic, clinical, modeling, and economic expertise to define modeling questions, generate hypotheses, identify and synthesize evidence through literature searches, determine and justify model inputs, and construct models that can address at least four of the five program areas. In other words, CDC is looking for teams that can operate across multiple disease domains and rapidly translate questions into credible analytic outputs.

Administratively, this opportunity was posted May 21, 2014, with a letter of intent due June 16, 2014, and a full application deadline of July 17, 2014 (11:59 p.m. Eastern) through Grants.gov. CDC also scheduled an informational conference call for potential applicants on June 3, 2014. The cooperative agreement mechanism signals that CDC anticipated substantial involvement and collaboration during the period of performance, which is typical when the funder expects ongoing technical coordination, priority-setting, and iterative analytic deliverables rather than a single standalone research project.

Funding details indicate an estimated total funding level of $15,000,000 with an expectation of three awards, and no cost-sharing or matching requirement. Award ceiling and floor amounts are listed as $0, which commonly means specific award sizes were not fixed in the synopsis and would instead be defined in the full announcement or negotiated based on scope. Eligible applicants were broad and included public and private colleges and universities, state and local governments and their agents (including territories), tribal governments and tribally designated organizations, public housing authorities/Indian housing authorities, nonprofit organizations with or without 501(c)(3) status, community- and faith-based organizations, for-profit organizations (other than small business), and small businesses. The opportunity is now archived (archive date August 16, 2014), but the summary reflects what CDC sought at the time: applied, policy-relevant economic modeling capacity to improve prevention decision-making across major infectious disease and school health priorities.

Frequently Asked Questions (FAQs)

What is the title and funding opportunity number for this CDC grant?

The opportunity is titled "Economic Modeling for HIV, Viral Hepatitis, Sexually Transmitted Diseases, Tuberculosis and School Health." The Funding Opportunity Number (FON) is CDC-RFA-PS14-1415.

What type of funding mechanism is this?

This is a discretionary cooperative agreement. That typically indicates CDC expected substantial involvement and collaboration during the project period, including coordination on priorities and iterative analytic deliverables rather than a single standalone research study.

What is the overall purpose of this funding opportunity?

The purpose is to strengthen how public health agencies and partners make prevention decisions by supporting well-built models and timely economic analyses. The aim is to help CDC and its National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) compare policy options, allocate limited resources, estimate intervention impacts, and assess cost-effectiveness.

Which program areas does CDC expect applicants to cover?

The work is focused on producing models and economic results across five program areas: HIV, viral hepatitis, sexually transmitted diseases (STDs), tuberculosis (TB), and school health.

What kinds of questions or decisions are the models expected to support?

The models are intended to provide decision support for high-priority prevention questions as programs, clinical recommendations, and public behaviors change. This includes comparing policy options, exploring resource allocation strategies across diseases and interventions, and estimating population-level impact and value of prevention activities supported or funded by NCHHSTP.

What types of modeling outputs and analyses are envisioned?

The opportunity describes analytic work such as estimating changes in incidence or prevalence when key drivers change, along with traditional economic assessments (cost of illness, intervention/program costs) and economic evaluation (cost-effectiveness). It also highlights return on investment (ROI) and net benefit analyses.

What are examples of "key drivers" that models may evaluate?

Examples mentioned include changes in sexual behaviors (such as condom use, uptake of pre-exposure prophylaxis (PrEP), or changes in antiretroviral therapy use), changes in health-seeking behaviors (such as increased HIV or hepatitis C testing), rollout or discontinuation of specific interventions, and shifts in prevention funding and program intensity.

Does the opportunity emphasize cost-effectiveness analysis?

Yes. Applicants are expected to be capable of cost-effectiveness analyses. The description notes that analyses may use quality-adjusted life years (QALYs) when comparing across different health problems, or use natural units (such as cases detected, infections averted, or patients treated) when comparing approaches within a specific disease area.

What is meant by "decision support" in this opportunity?

Decision support refers to building and using models to help determine optimal allocation of resources across diseases, interventions, and populations, and to estimate the overall population-level impact and value of prevention activities funded or supported by NCHHSTP.

Are return on investment (ROI) and net benefit analyses part of the expected deliverables?

Yes. ROI and net benefit analyses are specifically called out as key deliverable areas intended to translate public health strategies into economic terms to inform program planning, policy decisions, and recommendations.

Is CDC prescribing a single modeling method or framework?

No single method is specified. The opportunity implies flexibility in methods, as long as applicants can produce rigorous, defensible results that are usable for real-world public health decision-making.

What experience is CDC expecting from applicants?

Applicants are expected to show proven experience in economic modeling and analysis, including a demonstrated track record in at least two of the five program areas (HIV, viral hepatitis, TB, STDs, and school health).

How must the required experience be demonstrated?

The experience must be evidenced by prior peer-reviewed modeling or economic studies published in journals indexed in PubMed or EconLit.

How many program areas should an applicant be able to address?

Beyond the minimum track record in at least two areas, applicants should have enough expertise to construct models that can address at least four of the five program areas.

What types of expertise does CDC expect the applicant team to have?

The opportunity indicates teams should have enough epidemiologic, clinical, modeling, and economic expertise to define modeling questions, generate hypotheses, conduct literature searches, determine and justify model inputs, and construct models that can address multiple disease domains.

When was the opportunity posted and what were the key dates?

The opportunity was posted May 21, 2014. The letter of intent was due June 16, 2014. The full application deadline was July 17, 2014 at 11:59 p.m. Eastern, submitted through Grants.gov.

Was there an informational call for potential applicants?

Yes. CDC scheduled an informational conference call for potential applicants on June 3, 2014.

How were applications submitted?

Applications were due through Grants.gov by the stated deadline (July 17, 2014 at 11:59 p.m. Eastern).

What was the estimated total funding amount and expected number of awards?

The estimated total funding level was $15,000,000, with an expectation of three awards.

Was there a cost-sharing or matching requirement?

No. The opportunity states there was no cost-sharing or matching requirement.

Were award floor and ceiling amounts provided?

Award ceiling and floor amounts are listed as $0. The synopsis notes this commonly means specific award sizes were not fixed in the summary and would be defined in the full announcement or negotiated based on scope.

Who was eligible to apply?

Eligible applicants were broad and included: public and private colleges and universities; state and local governments and their agents (including territories); tribal governments and tribally designated organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status; community- and faith-based organizations; for-profit organizations (other than small business); and small businesses.

Is this funding opportunity still active?

No. The opportunity is archived, with an archive date of August 16, 2014.

Which CDC center is specifically mentioned as the main user of the analytic work?

The opportunity specifically references CDC's National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) as a key audience for the models and economic analyses.

What is the main practical value CDC describes for these models and economic analyses?

The summary emphasizes that models and timely economic analyses can quickly answer high-priority questions and help compare policy options, guide allocation of limited resources, estimate intervention impacts, and determine whether interventions are cost-effective.

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